Results 61 to 70 of about 9,817 (201)

Carbon ion radiotherapy: impact of tumor differentiation on local control in experimental prostate carcinomas

Radiation Oncology, 2017
Background To summarize the research activities of the “clinical research group heavy ion therapy”, funded by the German Research Foundation (DFG, KFO 214), on the impact of intrinsic tumor characteristics (grading, hypoxia) on local tumor control after ...
Christin Glowa, Peter Peschke, Stephan Brons, Oliver C. Neels, Klaus Kopka, Jürgen Debus, Christian P. Karger   +6 more
doaj   +1 more source

Strain, procedures, and tools for reproducible genetic transformation and genome editing of the emerging plant model Spirodela polyrhiza

New Phytologist, Volume 250, Issue 2, Page 735-756, April 2026.
Summary Duckweeds (Lemnaceae) have excellent potential for fundamental and applied research due to ease of cultivation, small size, and continuous fast clonal growth. However, their usage as model organisms and platforms for biotechnological applications is often limited by the lack of universal genetic manipulation methods necessary for transgene ...
Verónica Barragán‐Borrero, Amanda de Santana Lopes, Enrico Diniz Rodrigues Batista, Martin Höfer, Rana Elias, Abhisek Chakraborty, Arturo Ponce‐Mañe, Clotilde Descombes, Laura Diezma‐Navas, Lydia Petraki, Meret Huber, Shuqing Xu, Arturo Marí‐Ordóñez   +12 more
wiley   +1 more source

Comparing biological effectiveness guided plan optimization strategies for cranial proton therapy: potential and challenges

Radiation Oncology, 2022
Background To introduce and compare multiple biological effectiveness guided (BG) proton plan optimization strategies minimizing variable relative biological effectiveness (RBE) induced dose burden in organs at risk (OAR) while maintaining plan quality ...
Christian Hahn, Lena Heuchel, Jakob Ödén, Erik Traneus, Jörg Wulff, Sandija Plaude, Beate Timmermann, Christian Bäumer, Armin Lühr   +8 more
doaj   +1 more source

Generalizability of deep learning–based dose conversion model in proton beam therapy

Journal of Applied Clinical Medical Physics, Volume 27, Issue 3, March 2026.
Abstract Background In proton beam therapy (PBT), the analytical pencil beam (PB) algorithm involves dose uncertainties in inhomogeneous regions, making accurate Monte Carlo (MC) dose calculation desirable but time‐consuming. Deep learning, converting the dose calculated by the PB algorithm into an MC‐equivalent dose distribution, can resolve the trade‐
Ryohei Kato, Noriyuki Kadoya, Takahiro Kato, Ryota Tozuka, Shuta Ogawa, Masao Murakami, Keiichi Jingu   +6 more
wiley   +1 more source

The clinical relative biological effectiveness and prostate‐specific antigen kinetics of carbon‐ion radiotherapy in low‐risk prostate cancer

Cancer Medicine, 2023
Background To evaluate the clinical relative biological effectiveness (RBE) of carbon‐ion radiotherapy (C‐ion RT) for prostate cancer. Methods The records of 262 patients with low‐risk prostate cancer (median age, 65 [47–80] years) treated with C‐ion RT ...
Yu‐Mei Kang, Hitoshi Ishikawa, Taku Inaniwa, Yuma Iwai, Naruhiro Matsufuji, Goro Kasuya, Noriyuki Okonogi, Yu‐Ming Liu, Yee Chao, Masaru Wakatsuki, Hirohiko Tsujii, Hiroshi Tsuji   +11 more
doaj   +1 more source

On the use of quality factors and fluence to dose rate conversion in human radiation exposures [PDF]

, 1972
It is shown that various combinations of numbers and factors arrive at estimates of dose and dose effectiveness from values of fluence; but as yet it has not been possible to use biological data with the same degree of precision to estimate the physical ...
Sondhaus, C. A.
core   +1 more source

Clinical commissioning of a novel compact multi‐room pencil beam scanning proton therapy system

Journal of Applied Clinical Medical Physics, Volume 27, Issue 3, March 2026.
Abstract Purpose To present the clinical commissioning of the world's first multi‐room Varian ProBeam 360° proton pencil beam scanning system. Methods The state‐of‐the‐art system includes two clinical treatment rooms with 360° rotating gantries, a superconducting cyclotron, an energy selection system, a beam transport system and scanning nozzles. These
Eunsin Lee, Austin M Faught, Hyeri A Lee, Estelle Batin, Ahmet Ayan   +4 more
wiley   +1 more source

Mapping neutron biological effectiveness for DNA damage induction as a function of incident energy and depth in a human sized phantom

Scientific Reports
We present new developments for an ab-initio model of the neutron relative biological effectiveness (RBE) in inducing specific classes of DNA damage.
Alice Mentana, Virgilio Quaresima, Pavel Kundrát, Isabella Guardamagna, Leonardo Lonati, Ombretta Iaria, Andrea Previtali, Giorgia Santi Amantini, Luca Lunati, Virginia Boretti, Livio Narici, Luca Di Fino, Luca Bocchini, Claudio Cipriani, Giorgio Baiocco   +14 more
doaj   +1 more source

Archeo‐Inspiration from the Cultural History of Glass: Historic Accounts, Anecdotes and Hard Facts as Challenges to Modern Material Science

Advanced Materials, Volume 38, Issue 16, 17 March 2026.
Glass, historically valued for its purity and durability, has long inspired artists and societies. This article introduces the concept of “Archeo‐Inspiration”, drawing on cultural and historical contexts of glass to guide future material innovations.
Eva von Contzen, Julia von Ditfurth, Fabian Stroth, Bastian E. Rapp   +3 more
wiley   +1 more source

Biological Effects of Stellar Collapse Neutrinos [PDF]

, 1995
Massive stars in their final stages of collapse radiate most of their binding energy in the form of MeV neutrinos. The recoil atoms that they produce in elastic scattering off nuclei in organic tissue create radiation damage which is highly effective in ...
A. Drukier, D. M. Raup, D. Raup, D. T. Goodhead, D. T. Goodhead, J. Ellis, J. F. Ziegler, J. I. Collar, J. Kiefer, J. N. Bahcall, J. N. Bahcall, L. Sabatier, L. W. Brackenbusk, M. A. Kadhim, M. A. Ruderman, S. H. Jiang, S. M. Stanley, S. Z. Aghamohammadi, T. C. Yang, V. Michalik   +19 more
core   +2 more sources