Results 81 to 90 of about 9,817 (201)

Evaluation of specific RBE in different cells of hippocampus under high-dose proton irradiation in rats

Scientific Reports
The study aimed to determine the specific relative biological effectiveness (RBE) of various cells in the hippocampus following proton irradiation. Sixty Sprague–Dawley rats were randomly allocated to 5 groups receiving 20 or 30 Gy of proton or photon ...
Shengying Zhou, Xingchen Ding, Yiyuan Zhang, Yuanyuan Liu, Xiaowen Wang, Yujiao Guo, Jianguang Zhang, Xiao Liu, Guanzhong Gong, Ya Su, Lizhen Wang, Miaoqing Zhao, Man Hu   +12 more
doaj   +1 more source

RBE of Energetic Iron Ions for the Induction of Early and Late Chromosome Aberrations in Different Cell Types [PDF]

Numerous published studies have reported the Relative Biological Effectiveness (RBE) values for chromosome aberrations induced by charged particles of different LET.
Hada, Megumi, Kadhim, Munira, Wilson, Bobby, Wu, Honglu, Yeshitla, Samrawit, Zhang, Ye   +5 more
core   +2 more sources

Mapping Intestinal Paracellular Perm Eability in Mice: Regional and Cellular Variability Under Physiological and Stimulated Conditions

FASEB BioAdvances, Volume 8, Issue 3, March 2026.
This study analyzed the paracellular permeability of the intestines of healthy mice at a basal level. A new detection method involving tissue incubation for 5 min with luminal fluorescent dyes, such as FM1‐43FX (FM), which bind to accessible plasma (or external) cell membranes, was developed.
Mathilde Miquel, Kadirey Verwaerde, Anissa Edir‐Kibri, Mikael Albin, Florence Blas‐Y‐Estrada, Audrey Samper, Elodie Rousseau‐Bacquie, Hervé Robert, Hélène Eutamène, Vassilia Théodorou, Christine Coméra   +10 more
wiley   +1 more source

Cellular repair/misrepair track model [PDF]

A repair/misrepair cell kinetics model is superimposed onto the track structure model of Katz to provide for a repair mechanism. The model is tested on the repair-dependent data of Yang et al. and provides an adequate description of that data.
Cucinotta, Francis A., Wilson, John W.
core   +1 more source

Multiscale approach to radiation damage induced by ion beams: complex DNA damage and effects of thermal spikes

, 2010
We present the latest advances of the multiscale approach to radiation damage caused by irradiation of a tissue with energetic ions and report the most recent advances in the calculations of complex DNA damage and the effects of thermal spikes on ...
Solov'yov, A. V., Surdutovich, E., Yakubovich, A. V.   +2 more
core   +1 more source

Impact of Microdosimetric Modeling on Computation of Relative Biological Effectiveness for Carbon Ion Radiotherapy

Radiation
Microdosimetry plays a critical role in particle therapy by quantifying energy deposition within microscopic domains to assess biological effects. This study evaluates the influence of different microdosimetric functions (MFs) and domain geometries (DGs)
Shannon Hartzell, Keith M. Furutani, Alessio Parisi, Tatsuhiko Sato, Yuki Kase, Christian Deglow, Thomas Friedrich, Chris J. Beltran   +7 more
doaj   +1 more source

Variable relative biological effectiveness (RBE) in proton therapy of gliomas

, 2021
Derzeit gibt es eine intensive Debatte über die Notwendigkeit, Variationen der relativen biologischen Wirksamkeit (RBE) in der Protonentherapie zu berücksichtigen. Hier wurde die Variabilität der RBE für späte strahleninduzierte Hirnverletzungen (RIBI) untersucht, die nach einer Protonentherapie von Gliom-Hirntumorpatienten diagnostiziert wurden.
openaire   +1 more source

Interpreting the biological effects of protons as a function of physical quantity: linear energy transfer or microdosimetric lineal energy spectrum?

Scientific Reports
The choice of appropriate physical quantities to characterize the biological effects of ionizing radiation has evolved over time coupled with advances in scientific understanding.
Fada Guan, Lawrence Bronk, Matthew Kerr, Yuting Li, Leslie A. Braby, Mary Sobieski, Xiaochun Wang, Xiaodong Zhang, Clifford Stephan, David R. Grosshans, Radhe Mohan   +10 more
doaj   +1 more source

Empirical Relative Biological Effectiveness (RBE) for Mandible Osteoradionecrosis (ORN) in Head and Neck Cancer Patients Treated With Pencil-Beam-Scanning Proton Therapy (PBSPT): A Retrospective, Case-Matched Cohort Study. [PDF]

Front Oncol, 2022
Yang Y, Muller OM, Shiraishi S, Harper M, Amundson AC, Wong WW, McGee LA, Rwigema JM, Schild SE, Bues M, Fatyga M, Anderson JD, Patel SH, Foote RL, Liu W.   +14 more
europepmc   +1 more source

Radiation risk predictions for Space Station Freedom orbits [PDF]

Risk assessment calculations are presented for the preliminary proposed solar minimum and solar maximum orbits for Space Station Freedom (SSF).
Atwell, William, Cucinotta, Francis A., Hardy, Alva C., Katz, Robert, Shinn, Judy L., Townsend, Lawrence W., Weyland, Mark, Wilson, John W.   +7 more
core   +1 more source