Results 11 to 20 of about 1,064,021 (213)

Local and remote ischemic preconditioning protect against intestinal ischemic/reperfusion injury after supraceliac aortic clamping

Clinics, 2013
OBJECTIVES: This study tests the hypothesis that local or remote ischemic preconditioning may protect the intestinal mucosa against ischemia and reperfusion injuries resulting from temporary supraceliac aortic clamping.
Nilon Erling Junior, Edna Frasson de Souza Montero, Paulina Sannomiya, Luiz Francisco Poli-de-Figueiredo   +3 more
doaj   +2 more sources

Ischemic Preconditioning Improves Microvascular Endothelial Function in Remote Vasculature by Enhanced Prostacyclin Production [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
BACKGROUND The mechanisms underlying the effect of preconditioning on remote microvasculature remains undisclosed. The primary objective was to document the remote effect of ischemic preconditioning on microvascular function in humans.
Nicolai Rytter, Howard Carter, Peter Piil, Henrik Sørensen, Thomas Ehlers, Frederik Holmegaard, Christoffer Tuxen, Helen Jones, Dick Thijssen, Lasse Gliemann, Ylva Hellsten   +10 more
doaj   +3 more sources

Remote ischemic preconditioning in major vascular surgery [PDF]

Journal of Vascular Surgery, 2009
Remote ischemic preconditioning is a physiologic mechanism in mammalian species whereby brief exposure to nonlethal ischemia in one tissue confers protection against a prolonged ischemic insult in a distant tissue. First described almost 15 years ago, it has been slow to translate into clinical practice.
Walsh, Stewart R., Tang, Tjun Y., Sadat, Umar, Gaunt, Michael E.   +3 more
openaire   +4 more sources

Remote Ischemic Preconditioning and Outcomes of Cardiac Surgery [PDF]

New England Journal of Medicine, 2015
Whether remote ischemic preconditioning (transient ischemia and reperfusion of the arm) can improve clinical outcomes in patients undergoing coronary-artery bypass graft (CABG) surgery is not known. We investigated this question in a randomized trial.We conducted a multicenter, sham-controlled trial involving adults at increased surgical risk who were ...
Hausenloy, DJ, Candilio, L, Evans, R, Ariti, C, Jenkins, DP, Kolvekar, S, Knight, R, Kunst, G, Laing, C, Nicholas, J, Pepper, J, Robertson, S, Xenou, M, Clayton, T, Yellon, DM   +14 more
openaire   +6 more sources

Tranexamic Acid Does Not Influence Cardioprotection by Ischemic Preconditioning and Remote Ischemic Preconditioning

Anesthesia & Analgesia, 2018
Prior studies have suggested that the antifibrinolytic drug aprotinin increases the infarct size after ischemia and reperfusion (I/R) and attenuates the effect of ischemic preconditioning (IPC). Aprotinin was replaced by tranexamic acid (TXA) in clinical practice. Here, we investigated whether TXA influences I/R injury and/or cardioprotection initiated
van Caster, Patrick, Eiling, Sandra, Boekholt, Yvonne, Behmenburg, Friederike, Dorsch, Marianne, Heinen, André, Hollmann, Markus W., Huhn, Ragnar   +7 more
openaire   +3 more sources

The Effects of Remote Ischemic Preconditioning on the Inflammatory Cytokine Response to Free Flap Head and Neck Reconstruction: A Randomized Controlled Trial. [PDF]

Microsurgery
ABSTRACT Introduction Ischemia–reperfusion injury due to vascular pedicle occlusion is one of the most common causes of free flap failure in head and neck cancer reconstruction. Remote ischemic preconditioning (RIPC) has been proposed as an experimental, non‐invasive intervention to attenuate flap ischemia–reperfusion injury; however, the tissue ...
Nanthan KR, Larsen JB, Hvas CL, Kiil BJ, Krag AE.   +4 more
europepmc   +2 more sources

A RANDOMIZED COMPARATIVE STUDY BETWEEN REMOTE ISCHEMIC PRECONDITIONING AND PHARMACOLOGICAL PRECONDITIONING IN MAJOR AORTIC SURGERIES [PDF]

Ain Shams Medical Journal, 2020
Background: Cardiopulmonary bypass (CPB) remains an essential element of the surgical correction of most majorcardiovascular lesions. CPB is complicated by multisystem injury, the mechanisms of which include ischemia–reperfusion injury (IRI) and a ...
Mohamed Salama, John Naseef, Neveine Fahmy, Dalia Nasr, Gihan El Nasr   +4 more
doaj   +1 more source

Mechanisms and Prospects of Ischemic Tolerance Induced by Cerebral Preconditioning [PDF]

International Neurourology Journal, 2010
In the brain, brief episodes of ischemia induce tolerance against a subsequent severe episode of ischemia. This phenomenon of endogenous neuroprotection is known as preconditioning-induced ischemic tolerance.
Mohammad Iqbal Hossain Bhuiyan, Youn Jung Kim   +1 more
doaj   +1 more source

Anti-Inflammatory and Antipruritic Effects of Remote Ischaemic Postconditioning in a Mouse Model of Experimental Allergic Contact Dermatitis

Medicina, 2023
Background and Objectives: Allergic contact dermatitis is a common type IV hypersensitivity reaction characterised by redness, itching, oedema and thickening of the skin. It occurs in about 7% of the population and its incidence is increasing.
Ozgur Gunduz, Melike Sapmaz-Metin, Ruhan Deniz Topuz, Oktay Kaya, Cetin Hakan Karadag, Ahmet Ulugol   +5 more
doaj   +1 more source

The feasibility of an experimental model of donors after cardiac death in remote ischemic preconditioning studies for renal transplantation in porcine [PDF]

Acta Cirúrgica Brasileira, 2014
PURPOSE:To evaluate the feasibility of an experimental model of donors after cardiac death in remote ischemic preconditioning studies.METHODS: Twelve Landrace pigs were used as organ donors.
João Paulo Figueiredo Camarço, Lucio Kenny Morais, Juan Duque Moreno, Matheus Castrillon Rassi, Mylena Naves de Castro Rocha Camarço, Pedro Figueiredo Guimarães, Claudemiro Quireze Júnior   +6 more
doaj   +1 more source