Results 41 to 50 of about 1,064,021 (213)

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu   +3 more
wiley   +1 more source

The impact of remote ischemic preconditioning on cardiac biomarker and functional response to endurance exercise. [PDF]

open access: yes, 2017
Remote ischemic preconditioning (RIPC; repeated short reversible periods of ischemia) protects the heart against subsequent ischemic injury. We explored whether RIPC can attenuate post-exercise changes in cardiac troponin T (cTnT) and cardiac function in
Gaze, D.   +16 more
core   +1 more source

Opioids in Remote Ischemic Preconditioning-Induced Cardioprotection

open access: yesJournal of Cardiovascular Pharmacology and Therapeutics, 2016
Remote ischemic preconditioning (RIPC) is an intriguing process whereby transient regional ischemia and reperfusion episodes to remote tissues including skeletal, renal, mesenteric provide protection to the heart against sustained ischemia–reperfusion-induced injury.
Puneet Kaur, Randhawa   +1 more
openaire   +2 more sources

Glycopolymeric nanoparticles transported by activated platelets protect ischemic myocardium by alleviating PANoptosis through targeting macrophage Dectin‐1

open access: yesBMEMat, EarlyView.
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu   +13 more
wiley   +1 more source

Remote preconditioning by aortic constriction: affords cardioprotection as classical or other remote ischemic preconditioning? Role of iNOS [PDF]

open access: yes, 2011
Dose remote preconditioning by aortic constriction (RPAC) affords cardioprotection similar to classical or other remote ischemic preconditioning stimulus?
Ashok Sharma   +11 more
core  

Signalling pathways involved in TNFα-induced cytoprotection : role of reactive oxygen species [PDF]

open access: yes, 2005
Includes bibliographical references (leaves 73-89).Tumour necrosis factor alpha (TNFa) is a pleiotropic cytokine which has both beneficial and deleterious effects.
Lacerda, Lydia
core   +1 more source

The combination of Ling Jiao Gou Teng decoction and ischemic preconditioning protect against cerebral ischemic reperfusion injury in rats by protecting the blood brain barrier

open access: yesPharmacological Research - Modern Chinese Medicine, 2022
Ling Jiao Gou Teng decoction (LJGT) is a famous traditional Chinese medicine formula for treating ischemic stroke. It is not known whether the combination of LJGT and ischemic preconditioning can enhance the neuroprotective effect of cerebral ischemia ...
Zhen-zhen Chen, Xin Gong, Jianfeng Lei
doaj   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

Effects of dexmedetomidine in conjunction with remote ischemic preconditioning on renal ischemia–reperfusion injury in rats

open access: yesRevista Brasileira de Anestesiologia, 2014
Background and objectives: The aim of this study was to evaluate the effects of remote ischemic preconditioning by brief ischemia of unilateral hind limb when combined with dexmedetomidine on renal ischemia-reperfusion injury by histopathology and active
Emine Bagcik   +6 more
doaj   +1 more source

Remote and Anesthetic-Induced Myocardial Preconditioning Is Preserved in Atherosclerotic LDL Receptor-/- Mice In Vivo

open access: yesCardiovascular Therapeutics, 2021
Introduction. In the animal model, preconditioning is a powerful weapon against ischemic damage. The reason why the human heart cannot be protected from ischemic damage by preconditioning remains unclear.
Walter Petermichl   +6 more
doaj   +1 more source

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