Results 51 to 60 of about 4,100 (176)

Remote ischemic preconditioning for prevention of contrast induced nephropathy—Insights from an Indian study

Indian Heart Journal, 2018
Objectives: To study if four cycles of remote ischemic preconditioning (RIPC) could offer protection against contrast induced nephropathy (CIN) and post procedural renal dysfunction in high risk patients undergoing percutaneous coronary intervention (PCI)
Sanjai Pattu Valappil, Sivaprasad Kunjukrishnapillai, Sunitha Viswanathan, Alummoottil George Koshy, Prabha Nini Gupta, Radhakrishnan Vallikkattu Velayudhan, Mathew Iype   +6 more
doaj   +1 more source

Plasma exosomal miR‐339‐3p promotes myocardial remodeling in chronic heart failure by regulating USP25‐mediated DDX58 deubiquitination

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
In the patients of chronic heart failure (HF), miR‐339‐3p derived from plasma exosomes can target ubiquitin‐specific protease 25, inhibiting its K48‐linked deubiquitination modification of DDX58, leading to increased ubiquitination and degradation of DDX58.
Guoqiang Jing, Ting Xu, Yuhong Ma
wiley   +1 more source

Opioids in Remote Ischemic Preconditioning-Induced Cardioprotection

Journal of Cardiovascular Pharmacology and Therapeutics, 2016
Remote ischemic preconditioning (RIPC) is an intriguing process whereby transient regional ischemia and reperfusion episodes to remote tissues including skeletal, renal, mesenteric provide protection to the heart against sustained ischemia–reperfusion-induced injury.
Puneet Kaur, Randhawa, Amteshwar Singh, Jaggi   +1 more
openaire   +2 more sources

Circulating Nitrite Contributes to Cardioprotection by Remote Ischemic Preconditioning [PDF]

Circulation Research, 2014
Rationale: Remote ischemic preconditioning (rIPC) with short episodes of ischemia/reperfusion (I/R) of an organ remote from the heart is a powerful approach to protect against myocardial I/R injury. The signal transduction pathways for the cross talk between the remote
Rassaf, Tienush, Totzeck, Matthias, Hendgen-Cotta, Ulrike B., Shiva, Sruti, Heusch, Gerd, Kelm, Malte   +5 more
openaire   +2 more sources

Cardiac Remote Conditioning and Clinical Relevance: All Together Now!

Engineering, 2015
Acute myocardial infarction (AMI) is the leading cause of death and disability worldwide. Timely reperfusion is the standard of care and results in decreased infarct size, improving patient survival and prognosis.
Kristin Luther, Yang Song, Yang Wang, Xiaoping Ren, W. Keith Jones   +4 more
doaj   +1 more source

The Effects of Remote Ischemic Preconditioning on the Inflammatory Cytokine Response to Free Flap Head and Neck Reconstruction: A Randomized Controlled Trial

Microsurgery, Volume 46, Issue 6, September 2026.
ABSTRACT Introduction Ischemia–reperfusion injury due to vascular pedicle occlusion is one of the most common causes of free flap failure in head and neck cancer reconstruction. Remote ischemic preconditioning (RIPC) has been proposed as an experimental, non‐invasive intervention to attenuate flap ischemia–reperfusion injury; however, the tissue ...
Kumanan Rune Nanthan, Julie Brogaard Larsen, Christine Lodberg Hvas, Birgitte Jul Kiil, Andreas Engel Krag   +4 more
wiley   +1 more source

Remote Ischemic Preconditioning for Cardiac Surgery [PDF]

Circulation Research, 2016
Effect of remote ischemic preconditioning on clinical outcomes in patients undergoing coronary artery bypass graft surgery: the ERICCA Trial Hausenloy et al N Engl J Med . 2015;373:1408–1417. A multi-center trial of remote ischemic preconditioning for heart surgery Meybohm et al N Engl J Med. 2015;373:1397–1407.
Anweshan, Samanta, Buddhadeb, Dawn
openaire   +2 more sources

Ischemic and Pharmacological Preconditioning (part 2)

Общая реаниматология, 2012
This paper is the second part of an overview dealing with experimental and clinical studies in ischemic and pharmacological preconditioning. It considers the possibilities of practically using the available knowledge on the mechanisms of preconditioning,
V. V. Likhvantsev, V. V. Moroz, O. A. Grebenchikov, Yu. I., Gorokhovatsky, Yu. V. Zarzhetsky, S. S. Timoshin, D. I. Levikov, V. L. Shaibakova   +7 more
doaj   +1 more source

The Therapeutic Potential of Stem Cell Therapy for Doxorubicin‐Induced Cardiotoxicity: A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Doxorubicin (DOX) is a potent anthracycline chemotherapeutic agent whose clinical utility is significantly constrained by severe side effects, most notably DOX‐induced cardiotoxicity (DIC). Pathophysiological mechanisms of DIC include oxidative stress, mitochondrial dysfunction, programmed cell death, and inflammation ...
Ali Mirzaei, Pouria Rezaei, Reza Golchin Vafa, Saleheh Jahani, Reza Arefnezhad, Hossein Fatemian, Mohammad Hossein Nikoo, Amirhossein Sahebkar, Fatemeh Rezaei‐Tazangi   +8 more
wiley   +1 more source

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
wiley   +1 more source