Results 61 to 70 of about 4,100 (176)

Liver ischemia preconditions the heart against ischemia-reperfusion arrhythmias [PDF]

Iranian Journal of Basic Medical Sciences, 2015
Objective(s):This study aimed to examine the hypothesis that an antiarrhythmic effect might be obtained by ischemic preconditioning of the liver, and also to characterize the potential underlying mechanisms.
Mohammad-Foad Noorbakhsh, Hossein-Ali Arab, Hamid-Reza Kazerani   +2 more
doaj  

Ischial Pressure Ulcer Reconstruction: A Critical Review of the Paradigm Shift From Wound Coverage to Functional Restoration

Wound Repair and Regeneration, Volume 34, Issue 4, July/August 2026.
ABSTRACT Ischial pressure ulcers (IPUs), severe complications in patients with prolonged immobility, are challenging due to high recurrence. Moving beyond anatomical closure, the field now prioritises functional‐integrated reconstruction. This paradigm emphasises radical debridement and the transfer of well‐vascularized perforator flaps to obliterate ...
Chengying Huang, Shaohua Wang, Jielong Lin, Shunbin Wang, Zhaorong Xu   +4 more
wiley   +1 more source

Ischaemic pre‐conditioning improves workload, fatigue and recovery in team sport: A randomized, double‐blind, placebo‐controlled crossover trial

Experimental Physiology, Volume 111, Issue 7, Page 3322-3336, 1 July 2026.
Abstract Ischaemic preconditioning (IPC) is reported to improve performance, fatigue and recovery, yet evidence in team‐sport settings remains limited. We examined the effects of repeated IPC on external workload, perceptual strain and recovery during ecologically valid Gaelic football training.
Lorcan Daly, Shane Farrell, Alexander Gamble   +2 more
wiley   +1 more source

Concepts of hypoxic NO signaling in remote ischemic preconditioning

World Journal of Cardiology, 2015
Acute coronary syndromes remain a leading single cause of death worldwide. Therapeutic strategies to treat cardiomyocyte threatening ischemia/reperfusion injury are urgently needed. Remote ischemic preconditioning (rIPC) applied by brief ischemic episodes to heart-distant organs has been tested in several clinical studies, and the major body of ...
Totzeck, Matthias, Hendgen-Cotta, Ulrike B., Rassaf, Tienush   +2 more
openaire   +3 more sources

Data on the effects of remote ischemic preconditioning in the lungs after one-lung ventilation

Data in Brief, 2018
This article contains data on experimental endpoints of a randomized controlled animal trial. Fourteen healthy piglets underwent mechanical ventilation including injurious one-lung ventilation (OLV), seven of them experienced four cycles of remote ...
Astrid Bergmann, Christian Breitling, Göran Hedenstierna, Anders Larsson, Moritz Kretzschmar, Alf Kozian, Thomas Hachenberg, Thomas Schilling   +7 more
doaj   +1 more source

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

Animal Models and Experimental Medicine, Volume 9, Issue 6, Page 1126-1141, June 2026.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao, Chunlan Zou, Junxian Li, Yang Yang, Yuanyuan Han, Tingyu Ke   +5 more
wiley   +1 more source

Bilateral remote ischemic conditioning in children: A two-center, double-blind, randomized controlled trial in young children undergoing cardiac surgeryCentral MessagePerspective

JTCVS Open
Objective: The study objective was to determine whether adequately delivered bilateral remote ischemic preconditioning is cardioprotective in young children undergoing surgery for 2 common congenital heart defects with or without cyanosis.
Nigel E. Drury, PhD, FRCS(CTh), Carin van Doorn, MD, FRCS(CTh), Rebecca L. Woolley, MSc, Rebecca J. Amos-Hirst, MSc, Rehana Bi, BSc(Hons), Collette M. Spencer, BSc(Hons), Kevin P. Morris, MD, FRCPCH, James Montgomerie, MD, FRCA, John Stickley, BSc, Adrian Crucean, MD, Alicia Gill, MSc, Matt Hill, MSc, Ralf J.M. Weber, PhD, Lukas Najdekr, PhD, Andris Jankevics, PhD, Andrew D. Southam, PhD, Gavin R. Lloyd, PhD, Osama Jaber, MD, Imre Kassai, PhD, Giuseppe Pelella, MD, Natasha E. Khan, MD, FRCS(CTh), Phil Botha, PhD, FRCS(CTh), David J. Barron, MD, FRCS(CTh), Melanie Madhani, PhD, Warwick B. Dunn, PhD, Natalie J. Ives, MSc, Paulus Kirchhof, MD, Timothy J. Jones, MD, FRCS(CTh), Edmund D. Carver, Alistair J. Cranston, Fraser Harban, Vasco Laginha Rolo, Ritchie Marcus, Anthony Moriarty, Raju Reddy, Susanna N. Ritchie-McLean, Monica A. Stokes, Ayngara Thillaivasan, Nandlal Bhatia, Carol Bodlani, Wendy Lim, Joe Mellor, Jutta Scheffczik   +42 more
doaj   +1 more source

Limb ischemic preconditioning protects endothelium from oxidative stress by enhancing nrf2 translocation and upregulating expression of antioxidases. [PDF]

PLoS ONE, 2015
Remote ischemic preconditioning is often performed by limb ischemic preconditioning (LIPC), which has been demonstrated to be beneficial to various cells, including endothelial cells. The mechanisms underlying the protection have not been well clarified.
Min Chen, Mingsheng Zhang, Xuanping Zhang, Jie Li, Yan Wang, Yanying Fan, Ruizan Shi   +6 more
doaj   +1 more source

Cardiac preconditioning and cardiovascular diseases

Heart and Mind, 2017
Cardiovascular disease is the leading cause of mortality and morbidity in the United States. Cardiac preconditioning, an endogenous phenomenon, has been shown to protect the heart from acute myocardial infarction by subjecting it to brief cycles of ...
William A Li, Yuchuan Ding
doaj   +1 more source

Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics

MedComm, Volume 7, Issue 6, June 2026.
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou, Sheng He, Lili He, Kun Liu, Wen Tang, Deming Wang, Jing Gui, Zhiying Zeng, Yan Wang, Wenjie Liu, Ren Jing   +10 more
wiley   +1 more source