Results 81 to 90 of about 1,064,021 (213)

Limb ischemic preconditioning protects endothelium from oxidative stress by enhancing nrf2 translocation and upregulating expression of antioxidases. [PDF]

PLoS ONE, 2015
Remote ischemic preconditioning is often performed by limb ischemic preconditioning (LIPC), which has been demonstrated to be beneficial to various cells, including endothelial cells. The mechanisms underlying the protection have not been well clarified.
Min Chen, Mingsheng Zhang, Xuanping Zhang, Jie Li, Yan Wang, Yanying Fan, Ruizan Shi   +6 more
doaj   +1 more source

Neuromodulation Techniques in Chronic Cerebral Hypoperfusion: Mechanisms and Therapeutic Advances

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
Chronic cerebral hypoperfusion drives vascular cognitive impairment through neurovascular dysfunction, white matter injury, neuroinflammation, oxidative stress and synaptic network failure. Neuromodulation may offer a multi‐target strategy to restore plasticity, improve functional connectivity and support cognitive recovery. ABSTRACT Background Chronic
Chenye Qiao, Ning Li, Congxiao Wang, Yingpeng Wang, Jinglu Li, Hujun Wang, Zongjian Liu, Shuyan Qie   +7 more
wiley   +1 more source

Effect of remote ischemic preconditioning on renal dysfunction after complex valvular heart surgery: a randomized controlled trial. [PDF]

, 2011
OBJECTIVE: Acute kidney injury after cardiac surgery with cardiopulmonary bypass is closely related to systemic inflammatory reactions and oxidative stresses.
김종찬, 심재광, 최용선, 곽영란   +3 more
core   +2 more sources

Cardioprotection in coronary artery bypass graft surgery: the impact of remote ischemic preconditioning on modulating LOX-1 and SOD-1 to counteract oxidative stress

Frontiers in Cardiovascular Medicine
BackgroundCoronary artery bypass grafting (CABG) is frequently used to treat severe coronary artery disease (CAD), but it can lead to increased oxidative stress and inflammation, worsening patient outcomes. Remote ischemic preconditioning (RIPC) has been
Cezar-Dumitrel Luca, Cezar-Dumitrel Luca, Alexandra Boieriu, Alexandra Boieriu, Daniela Neculoiu, Daniela Neculoiu, Diana Țînț, Diana Țînț   +7 more
doaj   +1 more source

The Therapeutic Potential of Stem Cell Therapy for Doxorubicin‐Induced Cardiotoxicity: A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Doxorubicin (DOX) is a potent anthracycline chemotherapeutic agent whose clinical utility is significantly constrained by severe side effects, most notably DOX‐induced cardiotoxicity (DIC). Pathophysiological mechanisms of DIC include oxidative stress, mitochondrial dysfunction, programmed cell death, and inflammation ...
Ali Mirzaei, Pouria Rezaei, Reza Golchin Vafa, Saleheh Jahani, Reza Arefnezhad, Hossein Fatemian, Mohammad Hossein Nikoo, Amirhossein Sahebkar, Fatemeh Rezaei‐Tazangi   +8 more
wiley   +1 more source

Protecting the heart from ischemia/reperfusion injury: an update on remote ischemic preconditioning and postconditioning [PDF]

, 2017
Purpose of review: The most effective strategy for reducing acute myocardial ischemic injury is timely and effective reperfusion. However, myocardial reperfusion can induce further cardiomyocyte death (reperfusion injury).
Gelpi, Ricardo Jorge, Donato, Pablo Martín, Evelson, Pablo Andrés   +2 more
core   +1 more source

The effect of remote ischemic preconditioning on contralateral testicular morphology postI/R.

, 2023
A. Typical H&E-stained contralateral testicular sections after TI/R injury. sham: sham-operated; TI/R: testicular ischemia/reperfusion; RIPC (liver): remote liver ischemic preconditioning; RIPC (limb): remote limb ischemic preconditioning. Scale bars, 50
Ting Liu (45625), Qifeng Wang (123379), Shichao Wei (3452486), Quanhua Liu (9673184), Jiaxue Li (11924888), Zhaoyang Hu (312662), Zhibing Yan (17290891)   +6 more
core   +1 more source

Cardiac preconditioning and cardiovascular diseases

Heart and Mind, 2017
Cardiovascular disease is the leading cause of mortality and morbidity in the United States. Cardiac preconditioning, an endogenous phenomenon, has been shown to protect the heart from acute myocardial infarction by subjecting it to brief cycles of ...
William A Li, Yuchuan Ding
doaj   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, Volume 59, Issue 8, August 2026.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao, Lin Qi, Guijun Zou, Xingpeng Yang, Yizhao Ma, Zhifu Li, Xiaohui Du, Pengyue Zhao   +7 more
wiley   +1 more source

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

The Journal of Physiology, Volume 604, Issue 16, Page 6659-6674, 15 August 2026.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich, Ulas Ozkurede, Shanmugasundaram Pakkiriswami, Ryan Gemilere, Samira M. Azarin, Julia C. Liu   +5 more
wiley   +1 more source