Results 31 to 40 of about 4,100 (176)
Remote ischemic preconditioning in major vascular surgery [PDF]
Journal of Vascular Surgery, 2009 Remote ischemic preconditioning is a physiologic mechanism in mammalian species whereby brief exposure to nonlethal ischemia in one tissue confers protection against a prolonged ischemic insult in a distant tissue. First described almost 15 years ago, it has been slow to translate into clinical practice.
Walsh, Stewart R. +3 more
openaire +2 more sources
Immune mechanisms in cerebral ischemic tolerance
Frontiers in Neuroscience, 2014 Stressor-induced tolerance is a central mechanism in the response of bacteria, plants, and animals to potentially harmful environmental challenges.
Lidia eGarcia-Bonilla +4 more
doaj +1 more source
Anesthesia & Analgesia, 2018 Prior studies have suggested that the antifibrinolytic drug aprotinin increases the infarct size after ischemia and reperfusion (I/R) and attenuates the effect of ischemic preconditioning (IPC). Aprotinin was replaced by tranexamic acid (TXA) in clinical practice. Here, we investigated whether TXA influences I/R injury and/or cardioprotection initiated
van Caster, Patrick +7 more
openaire +2 more sources
BMC Surgery, 2011 Background Therapeutic strategies aiming to reduce ischemia/reperfusion injury by conditioning tissue tolerance against ischemia appear attractive not only from a scientific perspective, but also in clinics. Although previous studies indicate that remote
Kraemer Robert +6 more
doaj +1 more source
Neuroprotective and nephroprotective effects of remote postconditioning: Prospects for clinical use [PDF]
Терапевтический архив, 2016 The results of experimental and clinical studies strongly suggest that remote ischemic preconditioning (RIP) has no neuroprotective effect during cardiac surgery performed under extracorporeal circulation.
L N Maslov +7 more
doaj +1 more source
PLoS ONE, 2023 Testicular torsion is a urological emergency. However, surgical detorsion of the torsed spermatic cord can cause testicular reperfusion injury. Although remote ischemic preconditioning (RIPC) has been convincingly shown to protect organs against ischemia/
Jiaxue Li +6 more
doaj +1 more source
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
The regulation of stem cell fate and its application in neural regeneration
Interdisciplinary Medicine, EarlyView.Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He +3 more
wiley +1 more source
Pharmacological Research - Modern Chinese Medicine, 2022 Ling Jiao Gou Teng decoction (LJGT) is a famous traditional Chinese medicine formula for treating ischemic stroke. It is not known whether the combination of LJGT and ischemic preconditioning can enhance the neuroprotective effect of cerebral ischemia ...
Zhen-zhen Chen, Xin Gong, Jianfeng Lei
doaj +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia +6 more
wiley +1 more source