Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund +5 more
wiley +1 more source
Revisiting renin-angiotensin-aldosterone system in aging: translational insights from bench to bedside and back. [PDF]
Cosarderelioglu C, Abadir PM.
europepmc +1 more source
Cancer and Hypertension: Shared Mechanisms, Treatment Interactions, and Clinical Management
ABSTRACT Cancer and hypertension (HTN) frequently coexist, and their relationship is increasingly recognized as a clinically relevant intersection between oncology and cardiovascular medicine. However, the extent to which this association reflects shared risk factors, common biological mechanisms, or treatment‐related effects remains incompletely ...
Peizhi Jia +5 more
wiley +1 more source
Sodium-Glucose Co-Transporter 2 Inhibitors and Hyperkalemia-Related Discontinuation of Renin-Angiotensin-Aldosterone System Inhibitors During Mineralocorticoid Receptor Antagonist Therapy: A Real-World Cohort Study. [PDF]
Almalki AH +6 more
europepmc +1 more source
Hyperkalemia‐related sudden cardiac death (SCD) rates in US adults more than doubled from 1999 to 2020, with sharp increases after 2010. The burden was greatest among males, Black individuals, rural residents, and, surprisingly, younger adults—highlighting emerging disparities and the urgent need for improved potassium monitoring and chronic disease ...
Ibrahim Nagmeldin Hassan +4 more
wiley +1 more source
Correction: Alpha-7 nicotinic acetylcholine receptor: targeting the interplay between inflammation, renin-angiotensin aldosterone system, and nervous system for the novel treatment of heart failure. [PDF]
Swiderski J +6 more
europepmc +1 more source
Pulmonary hypertension is driven by dynamic crosstalk beyond the physical connection between the heart and lung, involving neurohormonal systems, immune pathways, and peripheral organs. This review highlights how multisystem signaling contributes to disease progression and may reveal new diagnostic and therapeutic targets.
Alejandro A. Vega +4 more
wiley +1 more source
Before the Pressure Rises: Intrarenal Renin-Angiotensin-Aldosterone System Activation in Normotensive Autosomal Dominant Polycystic Kidney Disease. [PDF]
Baker LW, Chebib FT.
europepmc +1 more source
Axial Connectivity of the Lung Microbiome: A Review of Interorgan Crosstalk
The human microbiome mediates immune homeostasis and metabolic signaling across organs. Beyond the gut‐lung axis, crosstalk between the lung and other organ systems is less recognized. This review assesses the axial connectivity of the lung microbiome across the gut, brain, skin, heart, kidney, and liver.
Mathangi Palanivel +2 more
wiley +1 more source
Perillyl alcohol attenuates hypoxia induced right ventricular dysfunction and remodeling by balancing the renin angiotensin aldosterone system in rats. [PDF]
Bai HJ +5 more
europepmc +1 more source

