Results 131 to 140 of about 22,692,331 (249)

Linderalactone mitigates diabetic renal injury by inhibiting macrophage inflammation via the Dectin1/Syk/CARD9/IRF5/NF‐κB pathway

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Background Inflammation plays an essential role in the pathogenesis of diabetic nephropathy (DN). Linderalactone (LNL), as a natural sesquiterpene lactone, has been discovered to have anti‐inflammatory activation. However, the effects of linderalactone on diabetes‐associated renal damage remain unclear.
Hao Chen   +7 more
wiley   +1 more source

Fenofibrate as a Modulator of the Renin-Angiotensin System in Su/Hx-Induced Pulmonary Arterial Hypertension. [PDF]

open access: yesInt J Mol Sci
Rada-Pascual KM   +13 more
europepmc   +1 more source

The biology of PKM2 in the metabolism and senescence in diabetic kidney disease

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley   +1 more source

Association between obstructive sleep apnea (OSA) and COVID‐19 severity

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Obstructive sleep apnea and sleep‐related hypoxia have been associated with higher rates of hospitalization and mortality among patients with Coronavirus disease 2019 (COVID‐19). We further explored the association between obstructive sleep apnea, COVID‐19 severity and related mortality.
Oria Nassi‐Liberman   +4 more
wiley   +1 more source

The Renin Angiotensin System and Bipolar Disorder: A Systematic Review

open access: bronze, 2020
Izabela Guimarães Barbosa   +6 more
openalex   +2 more sources

Moderate to Severe Obstructive Sleep Apnea Is a Risk Factor for Severe COVID‐19—A Nationwide Cohort Study

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT The impact of obstructive sleep apnea (OSA) and positive airway pressure (PAP) treatment on COVID‐19 severity is unclear. In this population‐based, nationwide study using multi‐register data, we aimed to assess if OSA is a risk factor for COVID‐19 severity and how adherence to PAP treatment and clinical characteristics affect the risk. Swedish
Mirjam Ljunggren   +7 more
wiley   +1 more source

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