Results 11 to 20 of about 865,582 (335)
The Renin-Angiotensin System Modulates Inflammatory Processes in Atherosclerosis: Evidence from Basic Research and Clinical Studies [PDF]
Mediators of Inflammation, 2009 Recent evidence shows that the renin-angiotensin system is a crucial player in atherosclerotic processes. The regulation of arterial blood pressure was considered from its first description of the main mechanism involved.
Mach, François +2 more
core +5 more sources
APOL1 Modulates Renin-Angiotensin System. [PDF]
BiomoleculesPatients carrying APOL1 risk alleles (G1 and G2) have a higher risk of developing Focal Segmental Glomerulosclerosis (FSGS); we hypothesized that escalated levels of miR193a contribute to kidney injury by activating renin–angiotensin system (RAS) in the ...
Kumar V +11 more
europepmc +2 more sources
Novel Antihypertensive Medications to Target the Renin-Angiotensin System: Mechanisms and Research. [PDF]
Rev Cardiovasc MedAn estimated 1.28 billion individuals in the global population suffer from hypertension. Importantly, uncontrolled hypertension is strongly linked to various cardiovascular and cerebrovascular diseases.
Jiang Z, Zhai C, Tang G.
europepmc +2 more sources
Renin Angiotensin System and Covid-19 Infection [PDF]
Advanced Pharmaceutical Bulletin, 2022 Purpose The new coronavirus, called SARS-CoV-2, is responsible for the recent global pandemic COVID-19. The status of the global pandemic COVID-19 is currently underway, and the virus has caused about 1.11 million deaths.
Francesco Ferrara, Antonio Vitiello
doaj +1 more source
Frontiers in Nutrition, 2021 Vitamin K2 (VK2), found to act to treat hypertension, has been widely used in the food and pharmaceutical industries nowadays. However, the potential targets and molecular mechanisms of VK2 for salt-sensitive hypertension have not been fully investigated.
Tian-hao Liu +7 more
doaj +1 more source
Hepcidin is potential regulator for renin activity.
PLoS ONE, 2022 An association between genetic variants in the genes HFE, HJV, BMP4 and arterial hypertension has been shown earlier. Proteins encoded by these genes participate in the signalling routes leading eventually to the production of the peptide hormone ...
Jaakko Piesanen +7 more
doaj +2 more sources
The renin–angiotensin system: a possible new target for depression
BMC Medicine, 2017 Depression remains a debilitating condition with an uncertain aetiology. Recently, attention has been given to the renin–angiotensin system. In the central nervous system, angiotensin II may be important in multiple pathways related to neurodevelopment ...
João Vian +9 more
doaj +1 more source
Cardio and neuro protection by renin angiotensin aldosterone system-focus inhibition angiotensin converting enzyme: A systematic review [PDF]
BIO Web of ConferencesOne of the incidences of cardiovascular disease is stroke, which is a disease that occurs due to impaired brain function caused by damage to cerebral blood circulation.
Capritasari Rafiastiana +2 more
doaj +1 more source
Direct pro-inflammatory effects of prorenin on microglia.
PLoS ONE, 2014 Neuroinflammation has been implicated in hypertension, and microglia have been proposed to play an important role in the progression of this disease. Here, we have studied whether microglia are activated within cardiovascular regulatory area(s) of the ...
Peng Shi +8 more
doaj +1 more source
Influence of Captopril Treatment of Plasma Renin Activity � Mathematical Model
Notulae Scientia Biologicae, 2010 A model of the dynamics of plasma renin activity under the influence of various doses of captopril is formulated. The influence of captopril on renin angiotensin system is different from the effects of the other studied drugs nifedipine and nicardipine.
Kaloyan Bonchev YANKOV +1 more
doaj +3 more sources