Results 121 to 130 of about 113,930 (262)

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Sex-Specific Blood Pressure and Brain Microvascular Traits in a Model of Low-Renin Hypertension. [PDF]

Hypertension
De Silva TM, Sabharwal R, Gerhold TD, Lynch C, Baumbach GL, Faraci FM.   +5 more
europepmc   +1 more source

Triptolide capsule enables proteinuria reduction and renal stabilization in advanced alport syndrome beyond standard therapy

Rheumatology &Autoimmunity, EarlyView.
Zhuo‐ran Song, Na Li, Yang Li, Hong Zhang, Xu‐jie Zhou   +4 more
wiley   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Broadening Primary Aldosteronism Screening: Alignment Across Contemporary Guidelines. [PDF]

Hypertension
Owei L, Wachtel H, Cohen JB.
europepmc   +1 more source

Improvement of Health‐Related Quality of Life and Mental Health After Unilateral Adrenalectomy for Primary Aldosteronism

Clinical Endocrinology, EarlyView.
ABSTRACT Background Primary aldosteronism (PA) has been linked with reduced health‐related quality of life (QoL) and increased prevalence of anxiety and depression. While most studies compared patients with PA to healthy subjects, this study focused on comparison with hypertensive patients without PA to identify PA‐specific effects.
Sybille Fuld, Christian Adolf, Georgiana Constantinescu, Manuel Schulze, Denise Brüdgam, Carmina T. Fuss, Hanna Remde, Lydia Kürzinger, Sven Gruber, Jun Yang, Amy Kang, Martin Reincke, Felix Beuschlein, Graeme Eisenhofer, Jacques W. M. Lenders, Christina Pamporaki   +15 more
wiley   +1 more source

Neuroendocrine responses to hemorrhagic shock in severe trauma: unraveling controversies and therapeutic implications. [PDF]

Crit Care
Yang Z, Jia Z.
europepmc   +1 more source

OSA Initiates Histone Lactylation That Drives PDE4B/FUS/AGT Axis to Pulmonary Hypertension

Cell Proliferation, EarlyView.
This study illustrates how chronic intermittent hypoxia (CIH) in obstructive sleep apnea (OSA) leads to hypertension via increased oxidative stress and mitochondrial dysfunction in pulmonary artery smooth muscle cells (PASMCs), causing glycolytic dysregulation. Lactate accumulation enhances histone lactylation, upregulating phosphodiesterase 4B (PDE4B),
Li Yang, Qing Ni, Yan He, Shijie Liu, Lulu Gan, Anni Dai, Yang Hu, Qian Liu, Xueling Yang, Jiqian Li, Yi Tao, Yunyu Li, Mingyue Xu   +12 more
wiley   +1 more source

COVID and the Renin-Angiotensin System: Are Hypertension or Its Treatments Deleterious?

Frontiers in Cardiovascular Medicine, 2020
Florian Zores, Mathieu E. Rebeaud
doaj   +1 more source

The joint-local renin-angiotensin system in rheumatoid arthritis and osteoarthritis: mechanistic evidence, disease-specific patterns, and translational perspectives. [PDF]

Rheumatol Int
Bilgin E, Haznedaroğlu İC.
europepmc   +1 more source