Results 121 to 130 of about 217,588 (352)

THE PATHOPHYSIOLOGY RELATIONSHIP OF HYPERTENSION AND RENAL HYPERTENSION

open access: yesJurnal Ilmiah Kedokteran Wijaya Kusuma, 2018
Introduction : Hypertension is a disease with an incidence rate is still high around the world, most of the causes of hypertension is unknown (essential hypertension / primary hypertension), a small portion of hypertension caused by diseases acquired ...
Akmarawita Kadir
doaj  

RENIN ANGIOTENSIN SYSTEM IN THE CONTEXT OF RENIN, PRORENIN, AND THE (PRO)RENIN RECEPTOR

open access: yesReviews in Agricultural Science, 2013
Since the discovery of renin by Tigerstedt in 1898, the complex roles of the components of the renin angiotensin system (RAS)have been extensively studied. RAS is involved in maintaining the homeostasis of body fluids and thus regulates the blood pressure.Renin is the key regulatory enzyme of RAS that catalyzes its only substrate angiotensinogen into ...
Tsutomu Nakagawa   +4 more
openaire   +2 more sources

Prognostic value of advanced lung cancer inflammation index in heart failure patients: A comprehensive analysis

open access: yesESC Heart Failure, EarlyView.
Abstract Aims The prognosis of heart failure (HF) is closely linked to inflammation and nutritional status. The advanced lung cancer inflammation index (ALI) is a composite indicator consisting of several parameters used to assess inflammation and nutritional status. Our study aimed to investigate the prognostic value of ALI in HF patients. Methods The
Wentao Chen   +3 more
wiley   +1 more source

Real‐world comparative effectiveness of sacubitril/valsartan versus RAS inhibition alone in patients with de novo heart failure

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Large‐scale, real‐world data on early initiation of sacubitril/valsartan in patients newly diagnosed (de novo) with HF with reduced ejection fraction (HFrEF) are limited. We examined the effectiveness of sacubitril/valsartan versus angiotensin‐converting enzyme inhibitor (ACEi)/angiotensin receptor blocker (ARB) on all‐cause and cause ...
Ankeet S. Bhatt   +6 more
wiley   +1 more source

A Novel Interaction Between Sympathetic Overactivity and Aberrant Regulation of Renin by miR-181a in BPH/2J Genetically Hypertensive Mice

open access: yesHYPERTENSION, 2013
Genetically hypertensive mice (BPH/2J) are hypertensive because of an exaggerated contribution of the sympathetic nervous system to blood pressure. We hypothesize that an additional contribution to elevated blood pressure is via sympathetically mediated ...
K. Jackson   +8 more
semanticscholar   +1 more source

Up‐titration of medication in patients with new‐onset heart failure with and without atrial fibrillation

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Differences in guideline‐directed medical therapy (GDMT) and clinical outcomes have been observed between heart failure (HF) patients with atrial fibrillation (AF) versus those in sinus rhythm. This study evaluated the effects of up‐titration of HF therapies, consisting of beta‐blockers, angiotensin‐converting‐enzyme inhibitors (ACEis ...
Arietje J.L. Zandijk   +6 more
wiley   +1 more source

Management of Patients with Adrenal Incidentalomas

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2014
The problem of choosing the tactics of the management of patients with adrenal incidentalomas is topical without doubt, considering the widespread use of modern instrumental methods for topical diagnosis.
L.А. Lutsenko
doaj   +1 more source

The ADESTE trial: A phase 2 study of enibarcimab, a monoclonal antibody targeting adrenomedullin, in acute heart failure

open access: yesESC Heart Failure, EarlyView.
Abstract Aims This study aimed to conduct a phase 2 proof‐of‐concept and safety study to evaluate the effect of ENIBARCIMAB (EN), a non‐neutralizing humanized monoclonal antibody targeting the N‐terminus of adrenomedullin (ADM), administered immediately after stabilization with standard of care (SoC) treatment, in patients hospitalized for acute heart ...
Anggoro Budi Hartopo   +19 more
wiley   +1 more source

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