Results 151 to 160 of about 229,829 (311)

Losartan Enhances Radiosensitivity by Reversing Immunosuppressive Tumor Microenvironment Induced by Radiotherapy in TNBC

Cancer Science, EarlyView.
Our study demonstrates that the angiotensin receptor blocker losartan enhances the efficacy of radiotherapy in triple‐negative breast cancer by reversing the immunosuppressive tumor microenvironment. Losartan reprograms tumor‐associated macrophages, inhibits myeloid‐derived suppressor cell function, and boosts CD8+ T‐cell activity.
Xu Wang, Cuiwei Liu, Zihan Xia, Ting Hu, Yuting Li, Dan Han, Yunjie Song, Yuxi Ma, Yanxia Zhao   +8 more
wiley   +1 more source

Unmasking Hormonal Mechanisms of Hypertension in Obesity. [PDF]

JACC Basic Transl Sci
Parisien-La Salle S, Tsai CH, Newman AJ, Chan JM, Milks J, Adler G, Ferrebus A, Hanna I, Mahrokhian S, Pitt B, Brown JM, Vaidya A.   +11 more
europepmc   +1 more source

Improvement of Health‐Related Quality of Life and Mental Health After Unilateral Adrenalectomy for Primary Aldosteronism

Clinical Endocrinology, EarlyView.
ABSTRACT Background Primary aldosteronism (PA) has been linked with reduced health‐related quality of life (QoL) and increased prevalence of anxiety and depression. While most studies compared patients with PA to healthy subjects, this study focused on comparison with hypertensive patients without PA to identify PA‐specific effects.
Sybille Fuld, Christian Adolf, Georgiana Constantinescu, Manuel Schulze, Denise Brüdgam, Carmina T. Fuss, Hanna Remde, Lydia Kürzinger, Sven Gruber, Jun Yang, Amy Kang, Martin Reincke, Felix Beuschlein, Graeme Eisenhofer, Jacques W. M. Lenders, Christina Pamporaki   +15 more
wiley   +1 more source

Is It Time to Retire Aldosterone Suppression Testing? [PDF]

Am J Hypertens
Kline GA, Leung AA, Orton D, MacFarlane J, Gurnell M.   +4 more
europepmc   +1 more source

Renal sodium handling and neurohumoral systems in patients with cirrhosis in sitting posture [PDF]

, 1993
Gerbes, Alexander L., Jüngst, Dieter, Pilz, A., Wernze, Heinrich   +3 more
core   +1 more source

Triptolide capsule enables proteinuria reduction and renal stabilization in advanced alport syndrome beyond standard therapy

Rheumatology &Autoimmunity, EarlyView.
Zhuo‐ran Song, Na Li, Yang Li, Hong Zhang, Xu‐jie Zhou   +4 more
wiley   +1 more source

Apparent Bilateral Aldosterone Suppression During Adrenal Vein Sampling: An Artefact of the Liaison Chemiluminescence Immunoassay and Other Causes Revealed by Comparisons With Another Commercial Immunoassay and Mass Spectrometry

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Subtyping of primary aldosteronism usually requires adrenal vein sampling (AVS). Interpretation can be compromised by apparent bilateral aldosterone suppression (ABAS), which we hypothesised reflects an artefact of the Liaison immunoassay of aldosterone.
Christina Pamporaki, Carmina T. Fuss, Ralph Kickuth, Lydia Kürzinger, Mirko Peitzsch, Sybille Fuld, Manuel Schulze, Jun Yang, Martin Reincke, Sven Gruber, Felix Beuschlein, Jacques W. M. Lenders, Graeme Eisenhofer   +12 more
wiley   +1 more source

ACTH and renin in 529 healthy youths: associations to sex, puberty and contraceptives. [PDF]

Endocr Connect
Edström PB, Holmboe SA, Vilmann L, Grøndahl VLR, Fritzbøger AFØ, Thomsen CE, Frederiksen H, Schrøder M, Jørgensen NR, Hagen CP, Aksglaede L, Ljubicic ML, Petersen JH, Juul A, Johannsen TH.   +14 more
europepmc   +1 more source

Obstructive sleep apnoea is associated with accelerated progression of diabetic kidney disease

Diabetic Medicine, EarlyView.
Abstract Aim Persons with type 2 diabetes and diabetic kidney disease (DKD) are at high risk of end‐stage kidney disease or death. We investigated the possible contribution of obstructive sleep apnoea (OSA) to decline in kidney function and renal outcomes.
Sebastian Nielsen, Martin B. Thomsen, Jakob Nyvad, Esben Laugesen, Erik Lerkevang Grove, Per Løgstrup Poulsen, Kent Lodberg Christensen, Mads Vaarby Sørensen, Peder Berg, Niels Henrik Buus   +9 more
wiley   +1 more source

Circulating DPP3 limits efficacy of angiotensin II infusion in septic shock. [PDF]

Crit Care
van Lier D, Santos K, Hartmann O, Kox M, Pickkers P.   +4 more
europepmc   +1 more source