Results 161 to 170 of about 261,257 (360)
Alimentary Pharmacology &Therapeutics, EarlyView.Indocyanine green clearance by pulse dye densitometry correlates with portal hypertension, systemic inflammation and circulatory dysfunction in advanced chronic liver disease. While diagnostic accuracy for CSPH was limited, ICG‐R15 independently predicted decompensation and ACLF/liver‐related mortality, highlighting its prognostic value across disease ...
Mathias Jachs +17 more
wiley +1 more source
Renin-Angiotensin Inhibition in Systolic Heart Failure and Chronic Kidney Disease
, 2012 Ali Ahmed +13 more
openalex +2 more sources
British Journal of Pharmacology, EarlyView.Background and Purpose Novel heart failure (HF) pharmacotherapies, including angiotensin receptor‐neprilysin inhibitor (ARNI) and sodium‐glucose cotransporter 2 inhibitors (SGLT2is), may confer cardiovascular benefits by attenuating myocardial fibrosis. However, direct evidence from human failing myocardial samples is limited.
Dávid Nagy +10 more
wiley +1 more source
Response to Method of Blood Collection May Explain the Suppression of Plasma Renin Concentration in Prorenin Transgenic Mice [PDF]
, 2009 Timothy L. Reudelhuber
openalex +1 more source
Cardiovascular Health in Women—Across the Lifespan
Clinical Endocrinology, EarlyView.ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar +5 more
wiley +1 more source
The Soluble (Pro)Renin Receptor in Health and Diseases: Foe or Friend? [PDF]
, 2021 Manman Qin, Chuanming Xu, Jun Yu
openalex +1 more source
OSA Initiates Histone Lactylation That Drives PDE4B/FUS/AGT Axis to Pulmonary Hypertension
Cell Proliferation, EarlyView.This study illustrates how chronic intermittent hypoxia (CIH) in obstructive sleep apnea (OSA) leads to hypertension via increased oxidative stress and mitochondrial dysfunction in pulmonary artery smooth muscle cells (PASMCs), causing glycolytic dysregulation. Lactate accumulation enhances histone lactylation, upregulating phosphodiesterase 4B (PDE4B),
Li Yang +12 more
wiley +1 more source
Angiotensin II receptor antagonists for the treatment of heart failure: what is their place after ELITE-II and Val-HeFT? [PDF]
, 2001 McMurray, John J.V.
core +1 more source