Results 31 to 40 of about 705,796 (337)

The dynamics and association of B and T cell receptor repertoires upon antibody response to hepatitis B vaccination in healthy adults

Human Vaccines & Immunotherapeutics, 2021
The Hepatitis B (HB) vaccine is efficacious in preventing hepatitis B virus infection. However, the association between antibody response to the HB vaccine and dynamic immune repertoire changes in different cell subsets remains unclear.
Miaoxian Zhao, Xueying Li, Shi Xie, Mingxing Gong, Rong Yan, Anqi Zheng, Ying Xu, Hongkai Wu, Zhanhui Wang   +8 more
doaj   +1 more source

Identification, Analysis and Characterization of Base Units of Bird Vocal Communication: The White Spectacled Bulbul (Pycnonotus xanthopygos) as a Case Study

Frontiers in Behavioral Neuroscience, 2022
Animal vocal communication is a broad and multi-disciplinary field of research. Studying various aspects of communication can provide key elements for understanding animal behavior, evolution, and cognition.
Aya Marck, Yoni Vortman, Oren Kolodny, Yizhar Lavner   +3 more
doaj   +1 more source

The impact of cryopreservation on cytokine secretion and polyfunctionality in human PBMCs: a comparative study

Frontiers in Immunology
IntroductionHuman peripheral blood mononuclear cells (hPBMCs) are widely used in fundamental research and clinical applications as studying their responses to in vitro activation is an effective way to uncover functional alterations and disease ...
Aline Linder, Kevin Portmann, Klaus Eyer, Klaus Eyer   +3 more
doaj   +1 more source

A Spontaneous Model of Experimental Autoimmune Encephalomyelitis Provides Evidence of MOG-Specific B Cell Recruitment and Clonal Expansion

Frontiers in Immunology, 2022
The key role of B cells in the pathophysiology of multiple sclerosis (MS) is supported by the presence of oligoclonal bands in the cerebrospinal fluid, by the association of meningeal ectopic B cell follicles with demyelination, axonal loss and reduction
Florent Salvador, Laure Deramoudt, Frédéric Leprêtre, Martin Figeac, Thomas Guerrier, Julie Boucher, Mathilde Bas, Nathalie Journiac, Anneli Peters, Lennart T. Mars, Hélène Zéphir, Hélène Zéphir, Hélène Zéphir   +12 more
doaj   +1 more source

Splenic B-1a Cells Expressing CD138 Spontaneously Secrete Large Amounts of Immunoglobulin in Naïve Mice

Frontiers in Immunology, 2014
B-1a cells constitutively secrete natural antibody that provides immediate protection against microbial pathogens and functions homeostatically to speed removal of apoptotic cell debris.
Nichol E Holodick, Teresa eVizconde, Thomas L Rothstein   +2 more
doaj   +1 more source

Extinction of gene expression in somatic cell hybrids. a reflection of important regulatory mechanisms? [PDF]

, 1993
Extinction in somatic cell hybrids is a multifactorial process that leads to loss of cell-type-specific gene expression. The underlying mechanisms are thought to mirror, at least in part, the repertoire of regulatory mechanisms controlling mammalian cell
Boshart, Michael, Nitsch, Doris, Schütz, Günther   +2 more
core   +1 more source

Inferring processes underlying B-cell repertoire diversity

, 2015
We quantify the VDJ recombination and somatic hypermutation processes in human B-cells using probabilistic inference methods on high-throughput DNA sequence repertoires of human B-cell receptor heavy chains.
Aleksandra M. Walczak, Curtis G. Callan, Dunn-Walters DK, Janeway C, Quentin Marcou, Shapiro GS, Shiokawa S, Stryer L, Thierry Mora, Yuval Elhanati, Zachary Sethna   +10 more
core   +1 more source

Stimulation-induced cytokine polyfunctionality as a dynamic concept

eLife
Cytokine polyfunctionality is a well-established concept in immune cells, especially T cells, and their ability to concurrently produce multiple cytokines has been associated with better immunological disease control and subsequent effectiveness during ...
Kevin Portmann, Aline Linder, Klaus Eyer
doaj   +1 more source

AIRR Community Standardized Representations for Annotated Immune Repertoires

Frontiers in Immunology, 2018
Increased interest in the immune system's involvement in pathophysiological phenomena coupled with decreased DNA sequencing costs have led to an explosion of antibody and T cell receptor sequencing data collectively termed “adaptive immune receptor ...
Jason Anthony Vander Heiden, Susanna Marquez, Nishanth Marthandan, Syed Ahmad Chan Bukhari, Christian E. Busse, Brian Corrie, Uri Hershberg, Uri Hershberg, Uri Hershberg, Steven H. Kleinstein, Steven H. Kleinstein, Frederick A. Matsen IV, Duncan K. Ralph, Aaron M. Rosenfeld, Chaim A. Schramm, The AIRR Community, Scott Christley, Uri Laserson   +17 more
doaj   +1 more source

The Linguistic Repertoire of a Young Adult, and a Middle Adult of a Ngaju Dayaknese Family in Central Kalimantan [PDF]

, 2013
This study is a qualitative study about linguistic repertoire and the subjects are three people from three different ages of a Ngaju Dayaknese family consisting of the mother, the first child and the third child.
Kesetiaan, K. (Kesy), Wijaya, H. P. (Henny)   +1 more
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