Results 31 to 40 of about 889,250 (400)
Although the anti-CCR4 antibody mogamulizumab (moga) shows striking antitumor activity against adult T cell leukemia (ATL), it can also cause fatal immunological pathology such as severe skin rash and graft-versus-host disease, which might be attributed ...
Takero Shindo +10 more
doaj +1 more source
Different B cell subpopulations show distinct patterns in their IgH repertoire metrics
Several human B cell subpopulations are recognised in the peripheral blood, which play distinct roles in the humoral immune response. These cells undergo developmental and maturational changes involving VDJ recombination, somatic hypermutation and class ...
Marie Ghraichy +5 more
doaj +1 more source
Using step width to compare locomotor biomechanics between extinct, non-avian theropod dinosaurs and modern obligate bipeds [PDF]
How extinct, non-avian theropod dinosaurs locomoted is a subject of considerable interest, as is the manner in which it evolved on the line leading to birds. Fossil footprints provide the most direct evidence for answering these questions. In this study,
Barrett, R S +10 more
core +1 more source
The human immune system is a fine network consisted of the innumerable numbers of functional cells that balance the immunity and tolerance against various endogenous and environmental challenges.
Tatsuo Ichinohe +8 more
doaj +1 more source
Architectural perspectives in the cathedral of Palermo : image-based modeling for cultural heritage understanding and enhancement [PDF]
Palermo off ers a repertoire of both artistic and architectural solid perspective of great beauty and in large quantity. This paper addresses the problem of the 3D survey of these works and their related study through the use of image-based modelling
Inzerillo, Laura, Santagati, Cettina
core +2 more sources
Commonality despite exceptional diversity in the baseline human antibody repertoire
In principle, humans can produce an antibody response to any non-self-antigen molecule in the appropriate context. This flexibility is achieved by the presence of a large repertoire of naive antibodies, the diversity of which is expanded by somatic ...
Bryan S. Briney +3 more
semanticscholar +1 more source
Intrathecal B-cell activation in LGI1 antibody encephalitis. [PDF]
ObjectiveTo study intrathecal B-cell activity in leucine-rich, glioma-inactivated 1 (LGI1) antibody encephalitis. In patients with LGI1 antibodies, the lack of CSF lymphocytosis or oligoclonal bands and serum-predominant LGI1 antibodies suggests a ...
Dandekar, Ravi +13 more
core
Good-enough principles for welfare [PDF]
The aim of this article is to widen the grounds of the debate on the relationship between values, social change and welfare reform. In the public debate on welfare reform and the Third Way the significance of the welfare politics and campaigns of civil ...
Williams, F.
core +1 more source
Norwegian Military Music and Edvard Grieg – an approach
Since both Edvard Grieg’s 175th birthday and Norwegian military music’s 200th anniversary are celebrated in 2018, a first look at compositions by Grieg for military music was in order. As one of Norway’s most popular and beloved composers, his works made
Ina Rupprecht
doaj +1 more source
Repertoire-dependent immunopathology [PDF]
In humans, limited T-cell receptor repertoire and lymphopenia are associated with severe eosinophilic inflammatory disease. A model of lymphopenia and reduced T-cell repertoire was created; C57BL/6 Rag2-/- mice received limited (30,000) or large (2 million) numbers of CD4 T-cells.
Joshua, Milner +4 more
openaire +2 more sources

