Results 61 to 70 of about 505,216 (312)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Search systems as a tool of socio-communicative structures of society
Інтегровані комунікації, 2020 The article analyses search engines as tools of social communication and searches for scientific information, presents a list of the newest national and world search engines, databases, repositories.
Ihor Rud
doaj +1 more source
University of Massachusetts Amherst Response to Draft Desirable Characteristics of Repositories for Managing and Sharing Data Resulting From Federally Funded Research [PDF]
, 2020 Response to the Office of Science and Technology Policy\u27s Draft Desirable Characteristics of Repositories for Managing and Sharing Data Resulting from Federally Funded Research.
Atwood, Thea P
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Concrete containers in radioactive waste management: a review
Brazilian Journal of Radiation Sciences, 2019 Nuclear power is considered a clean energy because it does not produce the gases responsible for greenhouse effect. However, like all human activities, it is susceptible to the generation of waste. With the increasing demand for energy in Brazil, the use
Barbara Lacerda Tavares +1 more
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Using a CRIS for e-Infrastructure: e-Infrastructure for Scholarly Publications
Data Science Journal, 2010 Scholarly publications are a major part of the research infrastructure. One way to make output available is to store the publications in Open Access Repositories (OAR).
E Dijk, M van Meel
doaj +1 more source
EMBRACE (EMbedding Repositories And Consortial Enhancement) project: final report [PDF]
, 2009 EMBRACE (EMBedding Repositories And Consortial Enhancement) was an 18-month project led by UCL on behalf of the SHERPA-LEAP (London Eprints Access Project) Consortium, a group of 13 University of London institutions with institutional repositories ...
Moyle, M., Stockley, R.
core
KULTUR: showcasing art through institutional repositories [PDF]
, 2010 Showcasing work has always been at the heart of the arts community, whether it be through an exhibition, site-specific installation or performance. Representation of the original work has also been important and use of print-based options like exhibition
Hemmings, C., White, W.
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source