Results 11 to 20 of about 496,166 (395)

Genome-Wide Characterization of R2R3-MYB Transcription Factors in Pitaya Reveals a R2R3-MYB Repressor HuMYB1 Involved in Fruit Ripening through Regulation of Betalain Biosynthesis by Repressing Betalain Biosynthesis-Related Genes [PDF]

open access: goldCells, 2021
The MYB (myeloblastosis) superfamily constitutes one of the most abundant transcription factors (TFs) regulating various biological processes in plants. However, the molecular characteristics and functions of MYB TFs in pitaya remain unclear. To date, no
Fangfang Xie   +8 more
doaj   +2 more sources

NUPR1 is a critical repressor of ferroptosis

open access: yesNature Communications, 2021
Ferroptosis is a type of iron-dependent regulated cell death, representing an emerging disease-modulatory mechanism. Transcription factors play multiple roles in ferroptosis, although the key regulator for ferroptosis in iron metabolism remains elusive ...
Jiao Liu   +7 more
semanticscholar   +1 more source

Two Retrotransposon Elements in Intron of Porcine BMPR1B Is Associated with Phenotypic Variation

open access: yesLife, 2022
It has been established that through binding to bone morphogenetic proteins (BMPs), bone morphogenetic protein receptor I B (BMPR1B) can mediate transforming growth factor β (TGF-β) signal transduction, and is involved in the regulation of several ...
Chenglin Chi   +9 more
doaj   +1 more source

CrgA Protein Represses AlkB2 Monooxygenase and Regulates the Degradation of Medium-to-Long-Chain n-Alkanes in Pseudomonas aeruginosa SJTD-1

open access: yesFrontiers in Microbiology, 2019
AlkB monooxygenases in bacteria are responsible for the hydroxylation of medium- and long-chain n-alkanes. In this study, one CrgA protein of Pseudomonas aeruginosa SJTD-1, a member of LysR family, was proved to regulate AlkB2 monooxygenase and the ...
Nannan Ji   +4 more
doaj   +1 more source

The KRAB Domain‐Containing Protein ZFP961 Represses Adipose Thermogenesis and Energy Expenditure through Interaction with PPARα

open access: yesAdvanced Science, 2022
Adipose thermogenesis plays a pivotal role in whole‐body metabolic homeostasis. Although transcriptional mechanisms that promote thermogenesis are extensively studied, the negative regulatory network is still poorly understood. Here, a Krüppel‐associated
Lei Huang   +3 more
doaj   +1 more source

The Transcription Repressor REST in Adult Neurons: Physiology, Pathology, and Diseases,,

open access: yeseNeuro, 2015
REST [RE1-silencing transcription factor (also called neuron-restrictive silencer factor)] is known to repress thousands of possible target genes, many of which are neuron specific.
P. Baldelli, J. Meldolesi
semanticscholar   +1 more source

Multiple binding sites for transcriptional repressors can produce regular bursting and enhance noise suppression [PDF]

open access: yes, 2017
Cells may control fluctuations in protein levels by means of negative autoregulation, where transcription factors bind DNA sites to repress their own production.
Lengyel, Iván M., Morelli, Luis G.
core   +2 more sources

Profiling of REST-dependent microRNAs reveals dynamic modes of expression

open access: yesFrontiers in Neuroscience, 2012
Multipotent neural stem cells (NSCs) possess the ability to self-renew and differentiate into both neurons and glia. However, the detailed mechanisms underlying NSC fate decisions are not well understood.
Zhengliang eGao   +2 more
doaj   +1 more source

A Gain-of-Function Mutant of IAA15 Inhibits Lateral Root Development by Transcriptional Repression of LBD Genes in Arabidopsis

open access: yesFrontiers in Plant Science, 2020
Lateral root development is known to be regulated by Aux/IAA-ARF modules in Arabidopsisthaliana. As components, several Aux/IAAs have participated in these Aux/IAA-ARF modules.
Sun Ho Kim   +8 more
doaj   +1 more source

Isolating intrinsic noise sources in a stochastic genetic switch [PDF]

open access: yes, 2011
The stochastic mutual repressor model is analysed using perturbation methods. This simple model of a gene circuit consists of two genes and three promotor states. Either of the two protein products can dimerize, forming a repressor molecule that binds to
Newby, J. M.
core   +2 more sources

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