Results 21 to 30 of about 332,235 (353)
AlkB monooxygenases in bacteria are responsible for the hydroxylation of medium- and long-chain n-alkanes. In this study, one CrgA protein of Pseudomonas aeruginosa SJTD-1, a member of LysR family, was proved to regulate AlkB2 monooxygenase and the ...
Nannan Ji+4 more
doaj +1 more source
Nucleotide sequence and mutational analysis of an immunity repressor gene from Bacillus subtilis temperate phage ϕ105 [PDF]
We have identified and sequenced a bacteriophage phi 105 gene encoding an immunity repressor, the first to be characterized from a temperate phage infecting a Gram-positive host.
De Smet, Bea+3 more
core +2 more sources
Switching off: the phenotypic transition to the uninduced state of the lactose uptake pathway [PDF]
The lactose uptake-pathway of E. coli is a paradigmatic example of multistability in gene-regulatory circuits. In the induced state of the lac-pathway, the genes comprising the lac-operon are transcribed, leading to the production of proteins which import and metabolize lactose.
arxiv +1 more source
A novel zinc finger transcriptional repressor, ZNF224, interacts with the negative regulatory element (AldA-NRE) and inhibits gene expression [PDF]
The interaction between the negative cis-element (AldA-NRE) and p97 repressor nuclear protein is a key step in modulating transcription of the human and mouse aldolase A (AldA) gene during the cell cycle and differentiation.
Agata+19 more
core +1 more source
Induced pluripotent stem cells (iPSCs) have been the focal point of ever increasing interest and scrutiny as they hold the promise of personalized regenerative medicine. However, creation of iPSCs is an inefficient process that requires forced expression of potentially oncogenic proteins.
Melissa Popowski, Haley Tucker
openaire +3 more sources
Adipose thermogenesis plays a pivotal role in whole‐body metabolic homeostasis. Although transcriptional mechanisms that promote thermogenesis are extensively studied, the negative regulatory network is still poorly understood. Here, a Krüppel‐associated
Lei Huang+3 more
doaj +1 more source
Two Retrotransposon Elements in Intron of Porcine BMPR1B Is Associated with Phenotypic Variation
It has been established that through binding to bone morphogenetic proteins (BMPs), bone morphogenetic protein receptor I B (BMPR1B) can mediate transforming growth factor β (TGF-β) signal transduction, and is involved in the regulation of several ...
Chenglin Chi+9 more
doaj +1 more source
NUPR1 is a critical repressor of ferroptosis [PDF]
AbstractFerroptosis is a type of iron-dependent regulated cell death, representing an emerging disease-modulatory mechanism. Transcription factors play multiple roles in ferroptosis, although the key regulator for ferroptosis in iron metabolism remains elusive.
Feimei Kuang+8 more
openaire +6 more sources
The MYB (myeloblastosis) superfamily constitutes one of the most abundant transcription factors (TFs) regulating various biological processes in plants. However, the molecular characteristics and functions of MYB TFs in pitaya remain unclear. To date, no
Fangfang Xie+8 more
doaj +1 more source
In grapevine, the MYB transcription factors play an important role in the flavonoid pathway. Here, a R2R3-MYB transcription factor, VvMYBC2L2, isolated from Vitis vinifera cultivar Yatomi Rose, may be involved in anthocyanin biosynthesis as a ...
Ziguo Zhu+6 more
doaj +1 more source