Results 21 to 30 of about 360,363 (303)

A 314-bp SINE insertion in the ZNF2 promoter region may act as a repressor related to regulation of fat deposition in pigs

open access: yesJournal of Integrative Agriculture, 2023
Retrotransposons, a type of DNA fragment that can mobilize itself on genome, can generate genetic variations and develop for molecular markers based on the insertion polymorphism.
Hao GU   +8 more
doaj   +1 more source

What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory systems [PDF]

open access: yes, 2014
Multistable gene regulatory systems sustain different levels of gene expression under identical external conditions. Such multistability is used to encode phenotypic states in processes including nutrient uptake and persistence in bacteria, fate ...
Berg, Johannes   +3 more
core   +2 more sources

Concentration and Length Dependence of DNA Looping in Transcriptional Regulation [PDF]

open access: yes, 2008
In many cases, transcriptional regulation involves the binding of transcription factors at sites on the DNA that are not immediately adjacent to the promoter of interest.
Beausang, John F.   +6 more
core   +13 more sources

Overexpression of PvPin1, a Bamboo Homolog of PIN1-Type Parvulin 1, Delays Flowering Time in Transgenic Arabidopsis and Rice

open access: yesFrontiers in Plant Science, 2017
Because of the long and unpredictable flowering period in bamboo, the molecular mechanism of bamboo flowering is unclear. Recent study showed that Arabidopsis PIN1-type parvulin 1 (Pin1At) is an important floral activator and regulates floral transition ...
Zhigang Zheng   +5 more
doaj   +1 more source

Optimizing periodicity and polymodality in noise-induced genetic oscillators [PDF]

open access: yes, 2011
Many cellular functions are based on the rhythmic organization of biological processes into self-repeating cascades of events. Some of these periodic processes, such as the cell cycles of several species, exhibit conspicuous irregularities in the form of
A. Sveiczer   +6 more
core   +3 more sources

Engineering orthogonal dual transcription factors for multi-input synthetic promoters [PDF]

open access: yes, 2016
Synthetic biology has seen an explosive growth in the capability of engineering artificial gene circuits from transcription factors (TFs), particularly in bacteria. However, most artificial networks still employ the same core set of TFs (for example LacI,
Broedel, AK, Isalan, M, Jaramillo, A
core   +2 more sources

Allelic expression mapping across cellular lineages to establish impact of non‐coding SNPs

open access: yesMolecular Systems Biology, 2014
Most complex disease‐associated genetic variants are located in non‐coding regions and are therefore thought to be regulatory in nature. Association mapping of differential allelic expression (AE) is a powerful method to identify SNPs with direct cis ...
Veronique Adoue   +16 more
doaj   +1 more source

Ten-eleven translocation proteins (TETs): tumor suppressors or tumor enhancers?

open access: yesFrontiers in Bioscience-Landmark, 2021
The epigenetic memory stored in the dynamic modifications, such as base modifications of cytosine (C) in DNA, including methylation/hydroxymethylation/demethylation, causes heritable phenotypes via regulating gene expression without alteration of DNA ...
Cuili Ma   +5 more
doaj   +1 more source

Crystallization and preliminary crystallographic analysis of dUTPase from the helper phage Φ11 of Staphylococcus aureus [PDF]

open access: yes, 2011
Staphylococcus aureus superantigen-carrying pathogenicity islands (SaPIs) have a determinant role in spreading virulence genes among bacterial populations that constitute a major health hazard.
Bendes, Ábris   +5 more
core   +1 more source

A R2R3-MYB Transcription Factor, VvMYBC2L2, Functions as a Transcriptional Repressor of Anthocyanin Biosynthesis in Grapevine (Vitis vinifera L.)

open access: yesMolecules, 2018
In grapevine, the MYB transcription factors play an important role in the flavonoid pathway. Here, a R2R3-MYB transcription factor, VvMYBC2L2, isolated from Vitis vinifera cultivar Yatomi Rose, may be involved in anthocyanin biosynthesis as a ...
Ziguo Zhu   +6 more
doaj   +1 more source

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