Results 21 to 30 of about 355,752 (283)
In grapevine, the MYB transcription factors play an important role in the flavonoid pathway. Here, a R2R3-MYB transcription factor, VvMYBC2L2, isolated from Vitis vinifera cultivar Yatomi Rose, may be involved in anthocyanin biosynthesis as a ...
Ziguo Zhu+6 more
doaj +1 more source
Operator Sequence Alters Gene Expression Independently of Transcription Factor Occupancy in Bacteria [PDF]
A canonical quantitative view of transcriptional regulation holds that the only role of operator sequence is to set the probability of transcription factor binding, with operator occupancy determining the level of gene expression.
Boedicker, James Q.+6 more
core +4 more sources
What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory systems [PDF]
Multistable gene regulatory systems sustain different levels of gene expression under identical external conditions. Such multistability is used to encode phenotypic states in processes including nutrient uptake and persistence in bacteria, fate ...
Berg, Johannes+3 more
core +2 more sources
Allelic expression mapping across cellular lineages to establish impact of non‐coding SNPs
Most complex disease‐associated genetic variants are located in non‐coding regions and are therefore thought to be regulatory in nature. Association mapping of differential allelic expression (AE) is a powerful method to identify SNPs with direct cis ...
Veronique Adoue+16 more
doaj +1 more source
The GbsR Family of Transcriptional Regulators: Functional Characterization of the OpuAR Repressor
Accumulation of compatible solutes is a common stress response of microorganisms challenged by high osmolarity; it can be achieved either through synthesis or import.
Stefanie Ronzheimer+4 more
doaj +1 more source
Ten-eleven translocation proteins (TETs): tumor suppressors or tumor enhancers?
The epigenetic memory stored in the dynamic modifications, such as base modifications of cytosine (C) in DNA, including methylation/hydroxymethylation/demethylation, causes heritable phenotypes via regulating gene expression without alteration of DNA ...
Cuili Ma+5 more
doaj +1 more source
Negative feedback control of jasmonate signaling by an alternative splice variant of JAZ10 [PDF]
The plant hormone jasmonate (JA) activates gene expression by promoting ubiquitin-dependent degradation of JAZ transcriptional repressor proteins. A key feature of all JAZ proteins is the highly conserved Jas motif, which mediates both JAZ degradation ...
Campos, Marcelo L.+7 more
core +1 more source
Sequence Dependence of Transcription Factor-Mediated DNA Looping [PDF]
DNA is subject to large deformations in a wide range of biological processes. Two key examples illustrate how such deformations influence the readout of the genetic information: the sequestering of eukaryotic genes by nucleosomes, and DNA looping in ...
Barry+62 more
core +3 more sources
Because of the long and unpredictable flowering period in bamboo, the molecular mechanism of bamboo flowering is unclear. Recent study showed that Arabidopsis PIN1-type parvulin 1 (Pin1At) is an important floral activator and regulates floral transition ...
Zhigang Zheng+5 more
doaj +1 more source
Isolating intrinsic noise sources in a stochastic genetic switch [PDF]
The stochastic mutual repressor model is analysed using perturbation methods. This simple model of a gene circuit consists of two genes and three promotor states. Either of the two protein products can dimerize, forming a repressor molecule that binds to
Newby, J. M.
core +2 more sources