Results 21 to 30 of about 491,654 (394)
Regulation of Αlpha-Synuclein Gene (SNCA) by Epigenetic Modifier TET1 in Parkinson Disease [PDF]
International Neurourology Journal, 2022 Purpose Deregulation of SNCA encoding α-synuclein (α-SYN) has been associated with both the familial and sporadic forms of Parkinson disease (PD). Epigenetic regulation plays a crucial role in PD.
Subhrangshu Guhathakurta +5 more
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Frontiers in Microbiology, 2022 Genetic alterations leading to the constitutive upregulation of specific efflux pumps contribute to antibacterial resistance in multidrug resistant bacteria.
Mireia López-Siles +2 more
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mSphere, 2020 Copper is broadly toxic to bacteria. As such, bacteria have evolved specialized copper export systems (cop operons) often consisting of a DNA-binding/copper-responsive regulator (which can be a repressor or activator), a copper chaperone, and a copper ...
Henrik O’Brien +5 more
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Two Retrotransposon Elements in Intron of Porcine BMPR1B Is Associated with Phenotypic Variation
Life, 2022 It has been established that through binding to bone morphogenetic proteins (BMPs), bone morphogenetic protein receptor I B (BMPR1B) can mediate transforming growth factor β (TGF-β) signal transduction, and is involved in the regulation of several ...
Chenglin Chi +9 more
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Profiling of REST-dependent microRNAs reveals dynamic modes of expression
Frontiers in Neuroscience, 2012 Multipotent neural stem cells (NSCs) possess the ability to self-renew and differentiate into both neurons and glia. However, the detailed mechanisms underlying NSC fate decisions are not well understood.
Zhengliang eGao +2 more
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Advanced Science, 2022 Adipose thermogenesis plays a pivotal role in whole‐body metabolic homeostasis. Although transcriptional mechanisms that promote thermogenesis are extensively studied, the negative regulatory network is still poorly understood. Here, a Krüppel‐associated
Lei Huang +3 more
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Role of the purine repressor hinge sequence in repressor function [PDF]
Journal of Bacteriology, 1994 A protease-hypersensitive hinge sequence in Escherichia coli purine repressor (PurR) connects an N-terminal DNA-binding domain with a contiguous corepressor-binding domain. Binding of one molecule of dimeric repressor to operator DNA protects the hinge against proteolytic cleavage.
K Y, Choi, H, Zalkin
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The Transcription Repressor REST in Adult Neurons: Physiology, Pathology, and Diseases,,
eNeuro, 2015 REST [RE1-silencing transcription factor (also called neuron-restrictive silencer factor)] is known to repress thousands of possible target genes, many of which are neuron specific.
P. Baldelli, J. Meldolesi
semanticscholar +1 more source
Multiple binding sites for transcriptional repressors can produce regular bursting and enhance noise suppression [PDF]
, 2017 Cells may control fluctuations in protein levels by means of negative autoregulation, where transcription factors bind DNA sites to repress their own production.
Lengyel, Iván M., Morelli, Luis G.
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Frontiers in Plant Science, 2020 Lateral root development is known to be regulated by Aux/IAA-ARF modules in Arabidopsisthaliana. As components, several Aux/IAAs have participated in these Aux/IAA-ARF modules.
Sun Ho Kim +8 more
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