Results 11 to 20 of about 201,151 (364)

Evidence-Based Structural Model of the Staphylococcal Repressor Protein: Separation of Functions into Different Domains. [PDF]

PLoS ONE, 2015
Horizontal transfer of mobile genetic elements within Staphylococci is of high biomedical significance as such elements are frequently responsible for virulence and toxic effects.
Kinga Nyíri, Bianka Kőhegyi, András Micsonai, József Kardos, Beata G Vertessy   +4 more
doaj   +1 more source

Rules of Expansion: an Updated Consensus Operator Site for the CopR-CopY Family of Bacterial Copper Exporter System Repressors

mSphere, 2020
Copper is broadly toxic to bacteria. As such, bacteria have evolved specialized copper export systems (cop operons) often consisting of a DNA-binding/copper-responsive regulator (which can be a repressor or activator), a copper chaperone, and a copper ...
Henrik O’Brien, Joseph W. Alvin, Sanjay V. Menghani, Yamil Sanchez-Rosario, Koenraad Van Doorslaer, Michael D. L. Johnson   +5 more
doaj   +1 more source

Repressor of temperate mycobacteriophage L1 harbors a stable C-terminal domain and binds to different asymmetric operator DNAs with variable affinity

Virology Journal, 2007
Background Lysogenic mode of life cycle of a temperate bacteriophage is generally maintained by a protein called 'repressor'. Repressor proteins of temperate lambdoid phages bind to a few symmetric operator DNAs in order to regulate their gene expression.
Mandal Nitai C, Das Malabika, Chanda Palas K, Chattoraj Partho, Bandhu Amitava, Ganguly Tridib, Sau Subrata   +6 more
doaj   +1 more source

Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development [PDF]

, 2001
MBD2 and MBD3 are closely related proteins with consensus methyl-CpG binding domains. MBD2 is a transcriptional repressor that specifically binds to methylated DNA and is a component of the MeCP1 protein complex.
Hendrich, B, Ramsahoye, B, Bird, A, Wilson, V A, Guy, J   +4 more
core   +1 more source

BiFCROS: A Low-Background Fluorescence Repressor Operator System for Labeling of Genomic Loci

G3: Genes, Genomes, Genetics, 2017
Fluorescence-based methods are widely used to analyze elementary cell processes such as DNA replication or chromosomal folding and segregation. Labeling DNA with a fluorescent protein allows the visualization of its temporal and spatial organization. One
Sarah Milbredt, Torsten Waldminghaus
doaj   +1 more source

A dominant repressor version of the tomatoSl-ERF.B3gene confers ethylene hypersensitivity via feedback regulation of ethylene signaling and response components [PDF]

, 2013
Ethylene Response Factors (ERFs) are downstream components of the ethylene signal transduction pathway, although their role in ethylene-dependent developmental processes remains poorly understood. As the ethylene-inducible tomato Sl-ERF.B3 has been shown
Kesari, Ravi, Roustan, Jean-Paul, Regad, Farid, Liu, Mingchun, Latché, Alain, Li, Zhengguo, Pech, Jean-Claude, Pirrello, Julien, Mila, Isabelle, Bouzayen, Mondher   +9 more
core   +1 more source

Clearance of an amyloid-like translational repressor is governed by 14-3-3 proteins

Cell Reports, 2022
Summary: Amyloids are fibrous protein aggregates associated with age-related diseases. While these aggregates are typically described as irreversible and pathogenic, some cells use reversible amyloid-like structures that serve important functions.
S. Grace Herod, Annie Dyatel, Stefanie Hodapp, Marko Jovanovic, Luke E. Berchowitz   +4 more
doaj   +1 more source

KPNB1 mediates PER/CRY nuclear translocation and circadian clock function

eLife, 2015
Regulated nuclear translocation of the PER/CRY repressor complex is critical for negative feedback regulation of the circadian clock of mammals. However, the precise molecular mechanism is not fully understood.
Yool Lee, A Reum Jang, Lauren J Francey, Amita Sehgal, John B Hogenesch   +4 more
doaj   +1 more source

C-terminal binding proteins: Emerging roles in cell survival and tumorigenesis [PDF]

, 2006
Within a cell, the levels and activity of multiple pro- and anti-apoptotic molecules act in concert to regulate commitment to apoptosis. Whilst the balance between survival and death can be tipped by the effects of single molecules, cellular apoptosis ...
Blaydes, J.P., J. P. Blaydes, Bergman, L.M., L. M. Bergman   +3 more
core   +1 more source

Mobility of the native Bacillus subtilis conjugative plasmid pLS20 is regulated by intercellular signaling.

PLoS Genetics, 2013
Horizontal gene transfer mediated by plasmid conjugation plays a significant role in the evolution of bacterial species, as well as in the dissemination of antibiotic resistance and pathogenicity determinants.
Praveen K Singh, Gayetri Ramachandran, Ricardo Ramos-Ruiz, Ramón Peiró-Pastor, David Abia, Ling J Wu, Wilfried J J Meijer   +6 more
doaj   +1 more source