BiFCROS: A Low-Background Fluorescence Repressor Operator System for Labeling of Genomic Loci
G3: Genes, Genomes, Genetics, 2017 Fluorescence-based methods are widely used to analyze elementary cell processes such as DNA replication or chromosomal folding and segregation. Labeling DNA with a fluorescent protein allows the visualization of its temporal and spatial organization. One
Sarah Milbredt, Torsten Waldminghaus
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The non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor. [PDF]
PLoS ONE, 2014 Jasmonate (JA) signalling is mediated by the JASMONATE-ZIM DOMAIN (JAZ) repressor proteins, which are degraded upon JA perception to release downstream responses. The ZIM protein domain is characteristic of the larger TIFY protein family. It is currently
Amparo Cuéllar Pérez +10 more
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Kaiso is a genome-wide repressor of transcription that is essential for amphibian development [PDF]
, 2004 DNA methylation in animals is thought to repress transcription via methyl-CpG specific binding proteins, which recruit enzymatic machinery promoting the formation of inactive chromatin at targeted loci.
Richard R. Meehan +13 more
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Virology Journal, 2007 Background Lysogenic mode of life cycle of a temperate bacteriophage is generally maintained by a protein called 'repressor'. Repressor proteins of temperate lambdoid phages bind to a few symmetric operator DNAs in order to regulate their gene expression.
Mandal Nitai C +6 more
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Repressor of Phage 16-3 with Altered Binding Specificity Indicates Spatial Differences in Repressor-Operator Complexes [PDF]
, 2006 The C repressor protein of phage 16-3, which is required for establishing and maintaining lysogeny, recognizes structurally different operators which differ by 2 bp in the length of the spacer between the conserved palindromic sequences.
Papp, P. Péter +2 more
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Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development [PDF]
, 2001 MBD2 and MBD3 are closely related proteins with consensus methyl-CpG binding domains. MBD2 is a transcriptional repressor that specifically binds to methylated DNA and is a component of the MeCP1 protein complex.
Hendrich, B +4 more
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KPNB1 mediates PER/CRY nuclear translocation and circadian clock function
eLife, 2015 Regulated nuclear translocation of the PER/CRY repressor complex is critical for negative feedback regulation of the circadian clock of mammals. However, the precise molecular mechanism is not fully understood.
Yool Lee +4 more
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Clearance of an amyloid-like translational repressor is governed by 14-3-3 proteins
Cell Reports, 2022 Summary: Amyloids are fibrous protein aggregates associated with age-related diseases. While these aggregates are typically described as irreversible and pathogenic, some cells use reversible amyloid-like structures that serve important functions.
S. Grace Herod +4 more
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PLoS Genetics, 2013 Horizontal gene transfer mediated by plasmid conjugation plays a significant role in the evolution of bacterial species, as well as in the dissemination of antibiotic resistance and pathogenicity determinants.
Praveen K Singh +6 more
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Evi-1 transforming and repressor activities are mediated by CtBP co-repressor proteins [PDF]
, 2001 Ectopic production of the EVI1 transcriptional repressor zinc finger protein is seen in 4--6% of human acute myeloid leukemias. Overexpression also transforms Rat1 fibroblasts by an unknown mechanism, which is likely to be related to its role in leukemia
Walker, Mark +6 more
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