Results 21 to 30 of about 191,078 (267)
Spatial epigenetic control of mono- and bistable gene expression. [PDF]
PLoS Biology, 2010 Bistability in signaling networks is frequently employed to promote stochastic switch-like transitions between cellular differentiation states. Differentiation can also be triggered by antagonism of activators and repressors mediated by epigenetic ...
János Z Kelemen +3 more
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The transcriptional repressor protein PRH interacts with the proteasome [PDF]
Biochemical Journal, 2003 PRH (proline-rich homeodomain protein)/Hex is important in the control of cell proliferation and differentiation. We have shown previously that PRH contains two domains that can bring about transcriptional repression independently; the PRH homeodomain represses transcription by binding to TATA box sequences, whereas the proline-rich N-terminal domain ...
Bess, KL +4 more
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The c1 repressor of bacteriophage P1. Isolation and characterization of the repressor protein.
Journal of Biological Chemistry, 1988 The c1 repressor gene of bacteriophage P1 is located on P1 DNA EcoRI fragment 7 (Sternberg, N. (1979) Virology 96, 129-142). Subfragments of P1 DNA EcoRI fragment 7 were cloned into expression vectors, and the c1 repressor protein from P1 wild-type phage and a revertant of a temperature-sensitive repressor mutant were overproduced in Escherichia coli ...
B, Dreiseikelmann +2 more
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The non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor.
PLoS ONE, 2014 Jasmonate (JA) signalling is mediated by the JASMONATE-ZIM DOMAIN (JAZ) repressor proteins, which are degraded upon JA perception to release downstream responses. The ZIM protein domain is characteristic of the larger TIFY protein family. It is currently
Amparo Cuéllar Pérez +10 more
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I. Biosynthesis of a Repressor/Nuclease Hybrid Protein
Journal of Biological Chemistry, 1989 The phage T7 endonuclease gene was fused to the 3' end of the lac repressor gene. The hybrid protein exhibits repressor and nuclease functions in a manner dependent on the conformation of the DNA. With supercoiled DNA, nuclease activity is directed to the major cruciform, whereas with linear DNA, the enzyme cleaves preferentially restriction fragments ...
N, Panayotatos, A, Fontaine, S, Bãckman
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Microbiology Spectrum, 2023 Stl, the master repressor of the Staphylococcus aureus pathogenicity islands (SaPIs), targets phage-encoded proteins to derepress and synchronize the SaPI and the helper phage life cycles. To activate their cycle, some SaPI Stls target both phage dimeric
Carla Sanz-Frasquet +4 more
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The STAR protein QKI-6 is a translational repressor [PDF]
Proceedings of the National Academy of Sciences, 1999 The signal transduction and activation of RNA (STAR) family of RNA-binding proteins, whose members are evolutionarily conserved from yeast to humans, are important for a number of developmental decisions. For example, in the mouse, quaking proteins (QKI-5, QKI-6, and QKI-7) are essential for ...
L, Saccomanno +5 more
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Plant Direct, 2023 The functions of closely related Myb‐like repressor and Myb‐like activator proteins within the plant circadian oscillator have been well‐studied as separate groups, but the genetic interactions between them are less clear.
Cassandra L. Hughes, Stacey L. Harmer
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Cholesterol, a repressor of natriuretic proteins
The FASEB Journal, 2019 Salt‐sensitivity in Dahl rats is due, in part, to the reduction of hemoxygenase‐1 (HO1), cyclooxygenase 2 (COX2), and nitric oxide synthase‐2 (NOS2) in the renal medulla. Renal overexpression of HIF1‐α, a regulator of HO1, COX2, and NOS2, enhances salt and water excretion and reduces blood pressure. Cholesterol (chol) incorporation into collecting duct
Robert Repetti +4 more
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Direct observation of dimerization between different CREB1 isoforms in a living cell. [PDF]
PLoS ONE, 2011 Cyclic AMP-responsive element binding protein 1 (CREB1) plays multiple functions as a transcription factor in gene regulation. CREB1 proteins are also known to be expressed in several spliced isoforms that act as transcriptional activators or repressors.
Hisayo Sadamoto +4 more
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