Results 31 to 40 of about 290,663 (301)

DEC2 modulates orexin expression and regulates sleep. [PDF]

open access: yes, 2018
Adequate sleep is essential for physical and mental health. We previously identified a missense mutation in the human DEC2 gene (BHLHE41) leading to the familial natural short sleep behavioral trait.
Fu, Ying-Hui   +7 more
core   +1 more source

The non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor.

open access: yesPLoS ONE, 2014
Jasmonate (JA) signalling is mediated by the JASMONATE-ZIM DOMAIN (JAZ) repressor proteins, which are degraded upon JA perception to release downstream responses. The ZIM protein domain is characteristic of the larger TIFY protein family. It is currently
Amparo Cuéllar Pérez   +10 more
doaj   +1 more source

Genome-Wide Identification, Functional Analysis and Expression Profiling of the Aux/IAA Gene Family in Tomato [PDF]

open access: yes, 2012
Auxin is a central hormone that exerts pleiotropic effects on plant growth including the development of roots, shoots, flowers and fruit. The perception and signaling of the plant hormone auxin rely on the cooperative action of several components,among
Abel   +55 more
core   +4 more sources

Modular Organization of the Phd Repressor/Antitoxin Protein [PDF]

open access: yesJournal of Bacteriology, 2004
ABSTRACT The P1 plasmid addiction operon is a compact genetic structure consisting of promoter, operator, antitoxin gene ( phd ), and toxin gene ( doc ). The 73-amino-acid antitoxin protein, Phd, has two distinct functions: it represses transcription (by binding to its operator) and
Jeremy Allen, Smith, Roy David, Magnuson
openaire   +2 more sources

The Bacteriophage–Phage-Inducible Chromosomal Island Arms Race Designs an Interkingdom Inhibitor of dUTPases

open access: yesMicrobiology Spectrum, 2023
Stl, the master repressor of the Staphylococcus aureus pathogenicity islands (SaPIs), targets phage-encoded proteins to derepress and synchronize the SaPI and the helper phage life cycles. To activate their cycle, some SaPI Stls target both phage dimeric
Carla Sanz-Frasquet   +4 more
doaj   +1 more source

Optimizing periodicity and polymodality in noise-induced genetic oscillators [PDF]

open access: yes, 2011
Many cellular functions are based on the rhythmic organization of biological processes into self-repeating cascades of events. Some of these periodic processes, such as the cell cycles of several species, exhibit conspicuous irregularities in the form of
A. Sveiczer   +6 more
core   +3 more sources

I. Biosynthesis of a Repressor/Nuclease Hybrid Protein

open access: yesJournal of Biological Chemistry, 1989
The phage T7 endonuclease gene was fused to the 3' end of the lac repressor gene. The hybrid protein exhibits repressor and nuclease functions in a manner dependent on the conformation of the DNA. With supercoiled DNA, nuclease activity is directed to the major cruciform, whereas with linear DNA, the enzyme cleaves preferentially restriction fragments ...
N, Panayotatos, A, Fontaine, S, Bãckman
openaire   +2 more sources

ArgR is an essential local transcriptional regulator of the arcABC-operon in Streptococcus suis and crucial for biological fitness in acidic environment [PDF]

open access: yes, 2011
Streptococcus suis is one of the most important pathogens in pigs and can also cause severe infections in humans. Despite its clinical relevance very little is known about the factors contributing to its virulence.
Benga, L.   +6 more
core   +2 more sources

Myb‐like transcription factors have epistatic effects on circadian clock function but additive effects on plant growth

open access: yesPlant Direct, 2023
The functions of closely related Myb‐like repressor and Myb‐like activator proteins within the plant circadian oscillator have been well‐studied as separate groups, but the genetic interactions between them are less clear.
Cassandra L. Hughes, Stacey L. Harmer
doaj   +1 more source

Characterization of the Radiation Desiccation Response Regulon of the Radioresistant Bacterium Deinococcus radiodurans by Integrative Genomic Analyses

open access: yesCells, 2021
Numerous genes are overexpressed in the radioresistant bacterium Deinococcus radiodurans after exposure to radiation or prolonged desiccation. It was shown that the DdrO and IrrE proteins play a major role in regulating the expression of approximately ...
Nicolas Eugénie   +7 more
doaj   +1 more source

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