Results 141 to 150 of about 244,153 (287)

The synergistic impact of granulocytic myeloid‐derived suppressor cells and innate lymphoid cells in systemic sclerosis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Systemic sclerosis (SSc) is a chronic autoimmune disorder characterized by immune dysregulation and fibrosis, with myeloid‐derived suppressor cells (MDSCs) emerging as important regulators of immune responses. However, the role of MDSCs in SSc‐associated fibrosis and their interactions with other immune cell populations remain poorly ...
Stefanie Weber   +15 more
wiley   +1 more source

Immersive virtual reality as a teaching tool in neuroanatomy: A scoping review

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Basic core courses in various undergraduate programs, such as neuroanatomy, pose a challenge for students due to the large volume and complexity of the content. In this context, educational technologies such as immersive virtual reality (IVR), which allow students to actively interact with learning materials, offer a complementary pedagogical ...
Nathálya Gardênia de Holanda Marinho Nogueira   +7 more
wiley   +1 more source

Adaptive imatinib regimens can mitigate cumulative toxicity while sustaining hemodynamic benefit: A model‐based simulation of the positioning imatinib for pulmonary arterial hypertension trial

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
ABSTRACT Aims Imatinib improves hemodynamics in pulmonary arterial hypertension (PAH), but dose‐dependent toxicity has limited its clinical development. We aimed to quantify the dose–efficacy–toxicity relationship and evaluate alternative dosing strategies using data from the PIPAH trial.
Medhat M. Said   +13 more
wiley   +1 more source

Sneak path current equivalent circuits and reading margin analysis of complementary resistive switches based 3D stacking crossbar memories

open access: yes, 2014
Sneak path currents of resistive memories is an important issue. They increase with increasing memory size and should be minimized for a usable resistive memory.
Mutlu, Reşat   +2 more
core   +1 more source

Quaestiones variae ex variis iuris Pontificii ac Caesarei sedibus collectae

open access: yes
de quibus ... pro adipiscendis in utroque iure insignibus, ac privilegiis doctoralibus disputabit Chrstianus Ram Stetinensis Pomer. Ad 9. Septemb.Enthält 24 ThesenDiss. iur.
Ram, Christian
core   +1 more source

Pistols and pride flags: How gender matters for boys in Welsh relationships and sexuality education

open access: yesBritish Educational Research Journal, EarlyView.
Abstract School‐based relationships and sexuality education (RSE) is a site of intense discursive circulation around the concept of gender. In the 2020s, international RSE curricula are responding to increasing visibility and cognisance of gendered and sexual diversity among young people and attempting to address gender‐based inequities and violence ...
Max R. Ashton
wiley   +1 more source

Scalable Separation and Purification of M13‐Bacteriophage‐Derived Particles Containing Artificial Single‐Stranded DNA Produced by Escherichia coli

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Single‐stranded DNA (ssDNA) solutions are promising innovations shaping the future of genetic research and medical therapies. In principle, biotechnological mass production of ssDNA can be achieved using Escherichia coli in a high‐cell density fed‐batch process by secreting phagemid particles derived from the filamentous M13 bacteriophages ...
Nathalie Hafner   +4 more
wiley   +1 more source

Purification of Disassembled Capsid Protein by Hydroxyapatite Chromatography Enhances Virus‐Like Particle Recovery

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Virus‐like particles (VLPs) are a promising modality with extensive applications in prophylactic and therapeutic vaccine design. Human Papillomavirus (HPV) vaccines are one such example where VLP vaccine applications have led to the successful reduction in HPV‐associated diseases, such as cervical cancer.
Nicholas Samuelson   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy