Examination of the APOBEC3 Barrier to Cross Species Transmission of Primate Lentiviruses
Viruses, 2021 The transmission of viruses from animal hosts into humans have led to the emergence of several diseases. Usually these cross-species transmissions are blocked by host restriction factors, which are proteins that can block virus replication at a specific ...
Amit Gaba, Ben Flath, Linda Chelico
doaj +1 more source
On stability of exponential cosmological solutions with non-static volume factor in the Einstein-Gauss-Bonnet model [PDF]
, 2016 A (n+1)-dimensional gravitational model with Gauss-Bonnet term and cosmological constant term is considered. When ansatz with diagonal cosmological metrics is adopted, the solutions with exponential dependence of scale factors: a_i ~ exp( v^i t), i = 1, .
Ivashchuk, V. D.
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SnapShot: Antiviral Restriction Factors
Cell, 2015 Restriction factors are cellular proteins that inhibit viruses at different steps of their replication cycle and represent an important first line of defense against viral pathogens. This SnapShot provides an overview of cell-intrinsic antiviral factors, describes their properties, and illustrates the striking variety of antiviral mechanisms as well ...
Silvia F. Kluge +2 more
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Eternally inflating cosmologies from intersecting spacelike branes [PDF]
, 2007 Intersecting spacelike braneworld cosmologies are investigated. The time axis is set on the scale parameter of extra space, which may include more than one timelike metric. Obtained are eternally inflating (i.e.
Chen C.-M. +3 more
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Restricted heterogeneity of polyclonal rheumatoid factors [PDF]
Arthritis & Rheumatism, 1987 AbstractThe electrophoretic pattern of rheumatoid factor (RF) was investigated in 40 polyclonal sera, by using radiolabeled IgG. Thirty sera specifically bound IgG aggregates, correlating with their RF titer. The binding pattern was monoclonal or oligoclonal.
J P, Bouvet, Y X, Wu, J, Pillot
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A Long Cytoplasmic Loop Governs the Sensitivity of the Anti-viral Host Protein SERINC5 to HIV-1 Nef
Cell Reports, 2018 We recently identified the multipass transmembrane protein SERINC5 as an antiviral protein that can potently inhibit HIV-1 infectivity and is counteracted by HIV-1 Nef.
Weiwei Dai +3 more
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Evolutionary Toggling of Vpx/Vpr Specificity Results in Divergent Recognition of the Restriction Factor SAMHD1 [PDF]
, 2013 SAMHD1 is a host restriction factor that blocks the ability of lentiviruses such as HIV-1 to undergo reverse transcription in myeloid cells and resting T-cells. This restriction is alleviated by expression of the lentiviral accessory proteins Vpx and Vpr
A Bergamaschi +47 more
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Unsupervised Rotation Factorization in Restricted Boltzmann Machines [PDF]
IEEE Transactions on Image Processing, 2020 Finding suitable image representations for the task at hand is critical in computer vision. Different approaches extending the original Restricted Boltzmann Machine (RBM) model have recently been proposed to offer rotation-invariant feature learning. In this paper, we present an extended novel RBM that learns rotation invariant features by explicitly ...
Mario Valerio Giuffrida +1 more
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New insights into an X-traordinary Viral Protein
Frontiers in Microbiology, 2014 Vpx is a protein encoded by members of the HIV-2/SIVsmm and SIVrcm/SIVmnd-2 lineages of primate lentiviruses, and which is packaged into viral particles.
Torsten eSchaller +4 more
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Classical basis for quantum spectral fluctuations in hyperbolic systems [PDF]
, 2003 We reason in support of the universality of quantum spectral fluctuations in chaotic systems, starting from the pioneering work of Sieber and Richter who expressed the spectral form factor in terms of pairs of periodic orbits with self-crossings and ...
Müller, Sebastian
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