Counteraction of the multifunctional restriction factor tetherin [PDF]
The interferon-inducible restriction factor tetherin (also known as CD317, BST-2 or HM1.24) has emerged as a key component of the antiviral immune response.
Daniel eSauter
doaj +3 more sources
The retroviral restriction factor TRIM5α
Retroviruses are obligate intracellular parasites that have coevolved with their hosts for millions of years. It is therefore not surprising that retroviruses take advantage of numerous host factors during their life cycle.
Luban, Jeremy, Sebastian, Sarah
core +4 more sources
On the restriction of the Fourier transform to polynomial curves [PDF]
We prove a Fourier restriction theorem on curves parametrised by the mapping P(t) = (P1(t),..., Pn(t)), where each of the P1,..., Pn is a real-valued polynomial and t belongs to an interval on which each of the P1,..., Pn "resembles" a ...
Dendrinos, S.
core +8 more sources
Antiretroviral restriction factors [PDF]
Studies of retroviruses have been instrumental in revealing the existence of an array of antiviral proteins, or restriction factors, and the mechanisms by which they function. Some restriction factors appear to specifically inhibit retrovirus replication, while others have a broader antiviral action. Here, we briefly review current understanding of the
Theodora, Hatziioannou, Paul D, Bieniasz
openaire +2 more sources
DR5 is a restriction factor for human herpesviruses. [PDF]
Restriction factors are dominant proteins that target different essential steps of the viral life cycle; thus, these proteins provide an early line of defense against viruses. Here, we found that the internalization of DR5, an important receptor of the extrinsic apoptotic pathway, initiates apoptosis to inhibit Kaposi sarcoma–associated herpesvirus ...
Han C, Gui C, Su B, Liu N, Yan H, Lan K.
europepmc +4 more sources
Antiretroviral restriction factors in mice [PDF]
One of the most exciting areas in contemporary retrovirus research is the discovery of "restriction factors". These are cellular proteins that act after virus entry to inhibit infection by or replication of retroviruses (and other viruses and intracellular pathogens).
Smita, Nair, Alan, Rein
openaire +2 more sources
Restricted 2-factor polytopes [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
William H. Cunningham, Yaoguang Wang
openaire +2 more sources
Evolutionary Toggling of Vpx/Vpr Specificity Results in Divergent Recognition of the Restriction Factor SAMHD1 [PDF]
SAMHD1 is a host restriction factor that blocks the ability of lentiviruses such as HIV-1 to undergo reverse transcription in myeloid cells and resting T-cells. This restriction is alleviated by expression of the lentiviral accessory proteins Vpx and Vpr
Emerman, M +23 more
core +2 more sources
Gene expression patterns of insulin-like growth factor 1, insulin-like growth factor 2 and insulin-like growth factor binding protein 3 in human placenta from pregnancies with intrauterine growth restriction [PDF]
Introduction: In this study, we compared insulin-like growth factor (IGF)-gene expression patterns and characteristics of glucose and insulin metabolism in human placenta from pregnancies with or without intrauterine growth restriction (IUGR).
Tóth, Katalin +23 more
core +1 more source
Effect of Dietary Restriction on Muscle Performance in Drosophila [PDF]
Dietary restriction (DR) can extend the lifespan in various organisms and is thought to present potential benefits in human. However, it is still a controversial issue now among scientists due to lack of strong supportive evidence in human.
Hsu, Pin-Chia
core +6 more sources

