Results 121 to 130 of about 88,526 (282)

Retinoblastoma protein regulates the crosstalk between autophagy and apoptosis, and favors glioblastoma resistance to etoposide [PDF]

open access: gold, 2013
Deborah Biasoli   +7 more
openalex   +1 more source

Statins in Breast Cancer Therapy: Mechanistic Insights and Emerging Evidence

open access: yesCancer Innovation, Volume 5, Issue 1, February 2026.
Statins, particularly simvastatin, demonstrate potential as adjuvant agents in breast cancer treatment by disrupting tumour cell signalling and survival pathways. This review highlights emerging evidence supporting their repurposing for improved outcomes, especially in aggressive breast cancer subtypes.
Rohina Alim, H. M. Kasuni Akalanka
wiley   +1 more source

Engineering Immortalized Bovine Granulosa Cells Using a Triple‐Gene Approach: Mutant CDK4, Cyclin D1, and TERT

open access: yesCell Biology International, Volume 50, Issue 2, February 2026.
ABSTRACT Advancing reproductive technologies in livestock is essential to improve both productivity and genetic potential of cattle. Despite this importance, application of reproductive biotechnologies in cattle breeding remains limited. Bovine granulosa cells (bGCs), which are key components of the ovarian follicle, are critical in female reproduction
Lanlan Bai   +12 more
wiley   +1 more source

Harnessing viral footprints in circulating free DNA (cfDNA) for early cancer detection: A focus on liquid‐biopsy‐based screening

open access: yesInternational Journal of Cancer, Volume 158, Issue 3, Page 511-526, 1 February 2026.
Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah   +4 more
wiley   +1 more source

Structure and function of the N-cadherin/catenin complex in retinoblastoma. [PDF]

open access: yes, 2002
PURPOSE. To identify in human retinoblastoma and normal retinal tissue the type of cadherin, its relationship with cytoplasmic catenins, and its participation in invasion. METHODS. The cadherin/catenin complex was characterized in surgical retinoblastoma.
Bruyneel, Erik   +8 more
core  

Radiogenomics: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Radiogenomics links imaging phenotypes with genetic variations, offering potential for comprehensive understanding, cost‐effective diagnosis, and prognosis prediction to advance personalized medicine. However, its clinical application remains limited by several challenges.
Xinyu Zhang   +8 more
wiley   +1 more source

Hypertension and age‐related focal global glomerulosclerosis are associated with biomarkers for cellular senescence

open access: yesPhysiological Reports, Volume 14, Issue 3, February 2026.
Abstract Arterionephrosclerosis is characterized by focal global glomerulosclerosis (FGGS), which is a constant feature of aging and hypertension. FGGS begins as normal‐appearing glomeruli that undergo tuft contraction (TC) and progress to global glomerulosclerosis (GGS).
Michael D. Hughson   +4 more
wiley   +1 more source

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