Results 121 to 130 of about 50,772 (264)

Retinoblastoma Protein Is Required for Epstein-Barr Virus Replication in Differentiated Epithelia. [PDF]

J Virol, 2023
Myers JE, Schaal DL, Nkadi EH, Ward BJH, Bienkowska-Haba M, Sapp M, Bodily JM, Scott RS.   +7 more
europepmc   +1 more source

Inactivation of oncoprotein binding by a single Cys706-to-Tyr substitution in the retinoblastoma protein

, 1994
We previously found a new single amino acid substitution at codon 706 (Cys-to-Tyr) of the retinoblastoma (RB) gene in a sporadic retinoblastoma patient.
Mitsuo V. Kato, Sasaki, Masao S., Taya, Yoichi, Kato, Mitsuo V., Kanji Ishizaki, Saijo, Masafumi, Masao S. Sasaki, Yoichi Taya, Ishizaki, Kanji, Masafumi Saijo   +9 more
core   +1 more source

Cutaneous Leiomyosarcoma of the Skin: An Updated Review of Epidemiology, Pathogenesis, and Management

International Journal of Dermatology, EarlyView.
This review provides an update on the epidemiology, pathogenesis, and clinical/histologic features of cutaneous leiomyosarcoma. Prognostic factors (e.g., depth of tumor involvement, grade, etc.) that can facilitate risk stratification are also discussed, as are treatment approaches for this rare malignancy.
Tejas P. Joshi, Natalie Garcia, Malak Husseinali, Nabeeha Engineer, Ikue Shimizu   +4 more
wiley   +1 more source

Prognostic and Clinicopathological Significance of the Loss of Expression of Retinoblastoma Protein (pRb) in Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis. [PDF]

Cancers (Basel), 2023
López-Ansio M, Ramos-García P, González-Moles MÁ.   +2 more
europepmc   +1 more source

Eag1 Gene and Protein Expression in Human Retinoblastoma Tumors and its Regulation by pRb in HeLa Cells

, 2020
Retinoblastoma is the most common pediatric intraocular malignant tumor. Unfortunately, low cure rates and low life expectancy are observed in low-income countries.
Zúñiga-García, Garrido, Avalos-Fuentes, Ponce-Castañeda, Escobar, Ortiz, Camacho, Sánchez-Ramos, Cabrera-Muñoz, Chávez-López, Vera, Hernández-Gallegos, Castro-Magdonel   +12 more
core   +1 more source

Role of the tomato MARS1/ROUGH gene encoding a LYSINE‐SPECIFIC HISTONE DEMETHYLASE 1 in adventitious root and fruit skin formation

Journal of Integrative Plant Biology, EarlyView.
The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba, Cécile Bres, Aurora Alaguero‐Cordovilla, Riyazuddin Riyazuddin, Qingyi Wang, Johann Petit, Jean‐Philippe Mauxion, Lara Caballero, David Latrasse, Bénédicte Bakan, Rim Brik‐Chaouche, David Esteve‐Bruna, Moussa Benhamed, Christophe Rothan, José Manuel Pérez‐Pérez   +14 more
wiley   +1 more source

Lack of Retinoblastoma Protein Shifts Tumor Metabolism from Glycolysis to OXPHOS and Allows the Use of Alternate Fuels. [PDF]

Cells, 2022
Suresh Babu V, Dudeja G, Sa D, Bisht A, Shetty R, Heymans S, Guha N, Ghosh A.   +7 more
europepmc   +1 more source

Complex Regulation of RETINOBLASTOMA‐RELATED's Interactions With E2Fs via Phosphorylation

Plant, Cell &Environment, EarlyView.
ABSTRACT Arabidopsis RETINOBLASTOMA‐RELATED (RBR) regulates cell proliferation by interacting with E2F transcription factors and DIMERISATION PARTNER, RB‐LIKE, E2F AND MULTI‐VULVAL CLASS B COMPLEX (DREAM) components. Although CDK‐CYCD phosphorylation is believed to affect RBR's E2F‐binding capacity, the precise phosphorylation events inhibiting RBR's ...
Aladár Pettkó‐Szandtner, Fruzsina Vadai‐Nagy, Magdolna Gombos, Attila Hlacs, Eszter Molnár, Annamária Marton, Csaba Vizler, Rasik Shiekh Bin Hamid, Péter Kaló, Attila Fehér, Zoltán Magyar   +10 more
wiley   +1 more source

Retinoblastoma protein as an intrinsic BRD4 inhibitor modulates small molecule BET inhibitor sensitivity in cancer. [PDF]

Nat Commun, 2022
Ding D, Zheng R, Tian Y, Jimenez R, Hou X, Weroha SJ, Wang L, Shi L, Huang H.   +8 more
europepmc   +1 more source

Pengaruh Pemberian Ekstrak Jintan Hitam (Nigella Sativa) terhadap Apoptosis pada Kultur Sel Retinoblastoma Melalui Ekspresi Protein E2F1 [PDF]

, 2018
Retinoblastoma merupakan kanker intraokular tersering yang terjadi pada anak. Retinoblastoma merupakan tumor neuroblastik yang diakibatkan oleh mutasi gen retinoblastoma (gen RB1) yang menyebabkan mutasi protein retinoblastoma (pRB), sehingga tidak ...
dr. Lely Retno Wulandari, Sp.M(K)., Aida, dr. Hariwati Moehariadi, Sp.M(K) ., dr. Hidayat Sujuti, Sp.M, Ph.D.   +3 more
core