Results 121 to 130 of about 3,403,478 (241)

An anti-cancer surveillance by the interplay between interferon-beta and retinoblastoma protein RB1. [PDF]

Front Oncol, 2023
Qin A.
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, Volume 20, Issue 9, Page 2356-2381, September 2026.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Retinoblastoma Protein Is Required for Epstein-Barr Virus Replication in Differentiated Epithelia. [PDF]

J Virol, 2023
Myers JE, Schaal DL, Nkadi EH, Ward BJH, Bienkowska-Haba M, Sapp M, Bodily JM, Scott RS.   +7 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, Volume 16, Issue 9, Page 1801-1812, September 2026.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Prognostic and Clinicopathological Significance of the Loss of Expression of Retinoblastoma Protein (pRb) in Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis. [PDF]

Cancers (Basel), 2023
López-Ansio M, Ramos-García P, González-Moles MÁ.   +2 more
europepmc   +1 more source

Lack of Retinoblastoma Protein Shifts Tumor Metabolism from Glycolysis to OXPHOS and Allows the Use of Alternate Fuels. [PDF]

Cells, 2022
Suresh Babu V, Dudeja G, Sa D, Bisht A, Shetty R, Heymans S, Guha N, Ghosh A.   +7 more
europepmc   +1 more source

Understanding the Epigenetic Landscape of Barrett's Esophagus and Esophageal Cancer: A Review of Current Findings, Caveats and Future Directions

Genes, Chromosomes and Cancer, Volume 65, Issue 9, September 2026.
ABSTRACT Esophageal cancer (OC) is currently the eighth most common form of cancer worldwide with a 5‐year survival rate of 10%–20%, with the primary risk factor of esophageal adenocarcinoma (OAC) being the development of Barrett's Esophagus (BO).
Louise Lawless, Trevor Doherty, Carla Surlis, Niamh Gilmartin, Therese M. Murphy   +4 more
wiley   +1 more source

Retinoblastoma protein as an intrinsic BRD4 inhibitor modulates small molecule BET inhibitor sensitivity in cancer. [PDF]

Nat Commun, 2022
Ding D, Zheng R, Tian Y, Jimenez R, Hou X, Weroha SJ, Wang L, Shi L, Huang H.   +8 more
europepmc   +1 more source

Nrf2–Keap1 Axis Modulation by Phytofabricated Metal Oxide Nanoparticles in Mesenchymal Stem Cell Lineage Bias

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Phytofabricated metal oxide nanoparticles may activate the Nrf2–Keap1 axis through a dual‐stimulus mechanism, coupling nanoparticle‐derived ROS with phytochemical‐mediated Keap1 modification, steering mesenchymal stem cells toward osteogenic commitment — a mechanistic framework this review consolidates from current evidence.
Muhammad Irfan, Muhammad Taha, Syed Muhammad Faizan Asghar, Muhammad Raza   +3 more
wiley   +1 more source

Nuclear Beclin 1 Destabilizes Retinoblastoma Protein to Promote Cell Cycle Progression and Colorectal Cancer Growth. [PDF]

Cancers (Basel), 2022
Pan Y, Zhao Z, Li J, Li J, Luo Y, Li W, You W, Zhang Y, Li Z, Yang J, Xiao ZJ, Wang Y.   +11 more
europepmc   +1 more source