Results 181 to 190 of about 50,772 (264)

The retinoblastoma protein contributes to maintaining the stability of HPV E7 in cervical cancer cells. [PDF]

J Virol
Gbala I, Kavcic N, Banks L.
europepmc   +1 more source

A highly stable RNA aptamer probe for the retinoblastoma protein in live cells. [PDF]

Chem Sci, 2020
Le TT, Bruckbauer A, Tahirbegi B, Magness AJ, Ying L, Ellington AD, Cass AEG.   +6 more
europepmc   +1 more source

CHD4 Orchestrates Chromatin Remodeling to Activate the c‐Myc Signaling Pathway in Cancer Pathogenesis

MedComm – Oncology, Volume 5, Issue 2, June 2026.
CHD4 plays an essential role as an epigenetic regulator in the pathogenesis of multiple myeloma. The chromatin remodeling protein initially resolves G‐quadruplex (G4) secondary structures within the c‐Myc promoter region, thereby enhancing chromatin accessibility and promoting transcriptional activation.
Pinggang Ding, Yuhao Cao, Zihao Liu, Jingru Xie, Lingling Liu, Shanliang Sun, Xichao Yu, Zhendong Deng, Zhimin Fan, Ye Yang, Chunyan Gu   +10 more
wiley   +1 more source

Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein pocket domain. [PDF]

J Biol Chem
Castro A, Ruiz Rivera A, Moorman CC, Wolf-Saxon ER, Mims HN, Vasquez Meza VI, Rangel MA, Loera MM, Bond IC, Buchanan SB, Villarreal E, Tripathi S, Rubin SM, Burke JR.   +13 more
europepmc   +1 more source

JI‐CJ002 and Dabrafenib Combination Enhances Antitumor Activity in Melanoma Associated With the Downregulation of B7‐H3

Cancer Science, Volume 117, Issue 6, Page 1651-1666, June 2026.
Schematic pathway diagram illustrating the effects of JI‐CJ002 and dabrafenib on melanoma progression. The combination of JI‐CJ002 and dabrafenib is associated with reduced B7‐H3 expression and modulation of signaling pathways implicated in melanoma progression, including JAK2/STAT3, PI3K/AKT/mTOR, and Rb/E2F1.
Sang‐Eun Lee, Young Ha Kim, Bo Shin Heo, Chunhoo Cheon, Seong‐Gyu Ko   +4 more
wiley   +1 more source

Retinoblastoma protein activity revealed by CRISPRi study of divergent Rbf1 and Rbf2 paralogs. [PDF]

G3 (Bethesda)
Raicu AM, Castanheira P, Arnosti DN.
europepmc   +1 more source

Dephosphorylation of the retinoblastoma protein during differentiation of HL60 cells.

, 1992
Immunoprecipitated retinoblastoma protein from HL60 cells migrated as a series of bands during electrophoresis. The heterogeneity appeared to be generated by phosphorylation of the retinoblastoma protein.
Eisenman, R N, Whyte, P
core  

Discovery of a Novel γ‐Glutamylcyclotransferase Inhibitor Plumbagin by Luminescence‐Based High‐Throughput Screening

Cancer Science, Volume 117, Issue 6, Page 1713-1723, June 2026.
A cell‐based high‐throughput screening system utilizing the luminescent probe LISA‐103 was developed to monitor γ‐glutamylcyclotransferase (GGCT) activity in cancer cells. Through this assay, plumbagin was identified as a novel GGCT inhibitor that induces cell cycle arrest and suppresses cancer cell growth. ABSTRACT γ‐Glutamylcyclotransferase (GGCT) is
Keiko Taniguchi, Yukie Nohara, Mano Horinaka, Kozue Nose, Masaya Mori, Hiromi Ii, Hiroko Kawakami, Kazuto Yano, Susumu Nakata, Taku Yoshiya, Toshiyuki Sakai   +10 more
wiley   +1 more source

The Traditional Chinese Medicine Formula <i>Modified Wu Bao San</i> Induces Cell Cycle Arrest and Apoptosis through Restoration of Retinoblastoma Protein Function and Inhibition of Aurora Kinase Activity. [PDF]

J Cancer
Chang CJ, Wu CC, Hsieh YJ, Chen JK, Kung YL, Tsai WT, Huang HS, Lin SZ, Ho TJ.   +8 more
europepmc   +1 more source

An E7-retinoblastoma protein pathway mechanism may account for the higher carcinogenic ability of HPV16 over HPV58 in cervical cancer. [PDF]

Transl Cancer Res
Zou J, Li Y, Chen T, Zhu C.
europepmc   +1 more source