Results 131 to 140 of about 357,868 (360)

Nanoplatform‐Enabled Genetic Interventions for Central Nervous System Disorders: Advances in Delivery Strategies and Therapeutic Potential

open access: yesAdvanced Genetics, EarlyView.
This review provides a detailed description of gene mutations and epigenetic mechanisms in central nervous system (CNS) disease, strategies for gene therapy, challenges for CNS gene therapy and gene‐drug nanocarriers. This review also summarizes the applications of nanogenetic therapy platforms in CNS diseases (brain tumors, neurodegenerative diseases,
Fuming Liang   +4 more
wiley   +1 more source

Case report: Successful therapy with azacitidine for acute myeloid leukemia with NUP98::RARG resembling acute promyelocytic leukemia

open access: yesFrontiers in Oncology
We report a case of acute myeloid leukemia (AML) with retinoic acid receptor gamma (RARG) rearrangement, exhibiting clinical, morphological, and immunophenotypic features similar to classic acute promyelocytic leukemia (APL).
Zhichen Wei   +9 more
doaj   +1 more source

Neuritogenic Activity of Trichostatin A in Adult Rat Retinal Ganglion Cells Through Acetylation of Histone H3 Lysine 9 and RARβ Induction

open access: yesJournal of Pharmacological Sciences, 2014
.: Like other CNS neurons, mature retinal ganglion cells (RGCs) cannot regenerate their axons after nerve injury due to loss of regenerative capacity. One of the reasons why they lose their capacity seems to be a dramatic shift in gene expression of RGCs
Yoshiki Koriyama   +3 more
doaj  

Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid. [PDF]

open access: bronze, 1991
Pierre Leroy   +7 more
openalex   +1 more source

Murine isoforms of retinoic acid receptor gamma with specific patterns of expression. [PDF]

open access: green, 1990
P Kastner   +7 more
openalex   +1 more source

Strategies for developing retinoic acid receptor alpha-selective antagonists as novel agents for male contraception. [PDF]

open access: yesEur J Med Chem, 2023
Al Noman MA   +12 more
europepmc   +1 more source

Retinoic acid receptor β2 agonists restore glycaemic control in diabetes and reduce steatosis

open access: yesDiabetes, obesity and metabolism, 2016
S. Trasino   +3 more
semanticscholar   +1 more source

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