Vitamin A and retinoid signaling: genomic and nongenomic effects
Journal of Lipid Research, 2013 Vitamin A or retinol is arguably the most multifunctional vitamin in the human body, as it is essential from embryogenesis to adulthood. The pleiotropic effects of vitamin A are exerted mainly by one active metabolite, all-trans retinoic acid (atRA ...
Ziad Al Tanoury +2 more
doaj
The Genetic Role of Retinoic Acid Receptors in Embryonic Development: Study of Genetic Mutations in Retinoic Acid Receptors, Resulting in Tissue Abnormalities [PDF]
, 2007 Retinoic acid (RA) is a vitamin A derivative that exerts profound influences in vertebrate development and physiology. All-trans RA and 9-cis RA, are important regulators of embryonic development, cellular activity and tissue homeostasis.
Ghaedi, Kamran. +2 more
core
Clinical Pharmacology in Drug Development, Volume 14, Issue 8, Page 614-620, August 2025.Abstract The aim of this study was to evaluate the bioequivalence and safety of a single application of crisaborole ointment to test formulation and reference formulation in healthy subjects under fasting conditions. A total of 32 subjects were included and divided into 2 groups (test‐reference; reference‐test).
Yanchao Wang +9 more
wiley +1 more source
Teratogenicity and Fetal-Transfer Assessment of the Retinoid X Receptor Agonist Bexarotene. [PDF]
ACS Pharmacol Transl Sci, 2022 Takamura Y +9 more
europepmc +1 more source
Identification of a Retinoid/Chicken Ovalbumin Upstream Promoter Transcription Factor Response Element in the Human Retinoid X Receptor γ2 Gene Promoter [PDF]
, 1997 Philip M. Barger, Daniel P. Kelly
openalex +1 more source
Microbiota–Host Interactions: Exploring Their Dynamics and Contributions to Human Diseases
MicrobiologyOpen, Volume 14, Issue 4, August 2025.Bacterial dysbiosis results from microbiota imbalances, diet, lifestyle, and other factors that lead to conditions such as IBS, IBD, acne, dermatitis, and dental diseases. The current therapeutic approaches include probiotics, prebiotics, synbiotics, microbiota transplantation, and phage therapy.
Siau Wui Chin +3 more
wiley +1 more source
Transcriptional control of nucleus accumbens neuronal excitability by retinoid X receptor alpha tunes sensitivity to drug rewards. [PDF]
Neuron, 2023 Godino A +12 more
europepmc +1 more source
Overexpressed Activated Retinoid X Receptors Can Mediate Growth Inhibitory Effects of Retinoids in Human Carcinoma Cells [PDF]
, 1998 Haisu Wan +3 more
openalex +1 more source
A coarse‐grained model for disordered proteins under crowded conditions
Protein Science, Volume 34, Issue 8, August 2025.Abstract Macromolecular crowding may strongly affect the dynamics and function of proteins, with intrinsically disordered proteins being particularly sensitive to their crowded environment. To understand the influences of crowding on chain compaction and phase separation (PS) behavior of disordered proteins, both experiments with synthetic crowders ...
Arriën Symon Rauh +2 more
wiley +1 more source
Ligand-dependent enhancement of human antithrombin gene expression by retinoid X receptor α and thyroid hormone receptor β [PDF]
, 1996 René W L M Niessen +5 more
openalex +1 more source