Results 111 to 120 of about 122,450 (299)
Dominant negative retinoid X receptor beta inhibits retinoic acid-responsive gene regulation in embryonal carcinoma cells. [PDF]
Saverio Minucci+6 more
openalex +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth+5 more
wiley +1 more source
In several species, a family of nuclear receptors, the peroxisome proliferator-activated receptors (PPARs) composed of three isotypes, is expressed in somatic cells and germ cells of the ovary as well as the testis.
Jaou-Chen Huang
doaj +1 more source
Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein. [PDF]
Thomas J. Berrodin+4 more
openalex +1 more source
ABSTRACT Rifampin is an enigma among antimicrobials. Blood and tissue compartment concentrations are a “moving target” along the treatment course due to the complex pharmacodynamic interactions within the body. Rifampin concomitant therapies are for the prevention and treatment of Rhodococcus equi infection in foals, for nearly 40 years.
Keith Edward Baptiste+4 more
wiley +1 more source
ABSTRACT Pityriasis rubra pilaris (PRP) is a rare, chronic papulosquamous disorder with limited treatment options in pediatric patients. We report the case of a 9‐year‐old boy with juvenile PRP (type III), who achieved complete disease remission after treatment with secukinumab, an IL‐17A inhibitor, following initial therapeutic resistance to topical ...
Zeno Fratton+2 more
wiley +1 more source
Phosphorylation enhances the target gene sequence-dependent dimerization of thyroid hormone receptor with retinoid X receptor. [PDF]
Manoj K. Bhat+2 more
openalex +1 more source
A Novel Tight Junction–Nuclear Receptor Signaling Pathway Regulating Cancer Progression
ABSTRACT Nuclear receptors (NRs) are lipid ligand‐binding transcription factors, with 48 members having been identified in humans to date. They are involved in diverse physiological processes, including development and homeostasis, and are also implicated in the pathogenesis of various diseases, most notably cancer.
Kotaro Sugimoto, Hideki Chiba
wiley +1 more source
ABSTRACT The diversification of Neotropical sigmodontine rodents represents one of the most remarkable evolutionary events among mammals, encompassing numerous endemic, rare, and endangered genera and species. One of the most emblematic examples is Microakodontomys transitorius Hershkovitz 1993, originally described from a single specimen based on ...
Marcelo Weksler+4 more
wiley +1 more source
Regulation of inflammatory and lipid metabolism genes by eicosapentaenoic acid-rich oil[S]
Omega-3-PUFAs, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), are associated with prevention of various aspects of metabolic syndrome.
Peter J. Gillies+5 more
doaj