Results 111 to 120 of about 122,450 (299)

Dominant negative retinoid X receptor beta inhibits retinoic acid-responsive gene regulation in embryonal carcinoma cells. [PDF]

open access: green, 1994
Saverio Minucci   +6 more
openalex   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth   +5 more
wiley   +1 more source

The Role of Peroxisome Proliferator-Activated Receptors in the Development and Physiology of Gametes and Preimplantation Embryos

open access: yesPPAR Research, 2008
In several species, a family of nuclear receptors, the peroxisome proliferator-activated receptors (PPARs) composed of three isotypes, is expressed in somatic cells and germ cells of the ovary as well as the testis.
Jaou-Chen Huang
doaj   +1 more source

Is Rifampin (Rifampicin) Essential for the Treatment of Rhodococcus equi Infections in Foals? A Critical Review of the Role of Rifampin

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Rifampin is an enigma among antimicrobials. Blood and tissue compartment concentrations are a “moving target” along the treatment course due to the complex pharmacodynamic interactions within the body. Rifampin concomitant therapies are for the prevention and treatment of Rhodococcus equi infection in foals, for nearly 40 years.
Keith Edward Baptiste   +4 more
wiley   +1 more source

Classical Juvenile Pityriasis Rubra Pilaris Treated With Secukinumab: Case Report and a Review of Biological Treatments in the Pediatric Population

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Pityriasis rubra pilaris (PRP) is a rare, chronic papulosquamous disorder with limited treatment options in pediatric patients. We report the case of a 9‐year‐old boy with juvenile PRP (type III), who achieved complete disease remission after treatment with secukinumab, an IL‐17A inhibitor, following initial therapeutic resistance to topical ...
Zeno Fratton   +2 more
wiley   +1 more source

A Novel Tight Junction–Nuclear Receptor Signaling Pathway Regulating Cancer Progression

open access: yesPathology International, EarlyView.
ABSTRACT Nuclear receptors (NRs) are lipid ligand‐binding transcription factors, with 48 members having been identified in humans to date. They are involved in diverse physiological processes, including development and homeostasis, and are also implicated in the pathogenesis of various diseases, most notably cancer.
Kotaro Sugimoto, Hideki Chiba
wiley   +1 more source

Systematics of the Enigmatic Neotropical Rodent Genus Microakodontomys (Cricetidae: Sigmodontinae): New Evidence Supporting Its Distinctiveness and Endangered Status

open access: yesZoologica Scripta, EarlyView.
ABSTRACT The diversification of Neotropical sigmodontine rodents represents one of the most remarkable evolutionary events among mammals, encompassing numerous endemic, rare, and endangered genera and species. One of the most emblematic examples is Microakodontomys transitorius Hershkovitz 1993, originally described from a single specimen based on ...
Marcelo Weksler   +4 more
wiley   +1 more source

Regulation of inflammatory and lipid metabolism genes by eicosapentaenoic acid-rich oil[S]

open access: yesJournal of Lipid Research, 2012
Omega-3-PUFAs, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), are associated with prevention of various aspects of metabolic syndrome.
Peter J. Gillies   +5 more
doaj  

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