Results 31 to 40 of about 43,565 (303)

Retinoids in cancer chemoprevention and therapy: Meta-analysis of randomized controlled trials

open access: yesFrontiers in Genetics, 2022
Retinoids, natural and synthetic derivatives of vitamin A, have many regulatory functions in human body, including regulating cellular proliferation, differentiation, apoptosis. Moreover, retinoids have been used successfully for the treatment of certain
Shuting Chen   +20 more
doaj   +1 more source

Advances in Preventive Therapy for Estrogen-Receptor-Negative Breast Cancer. [PDF]

open access: yes, 2014
Preventing breast cancer is an effective strategy for reducing breast cancer deaths. The purpose of chemoprevention (also termed preventive therapy) is to reduce cancer incidence by use of natural, synthetic, or biological agents.
Brown, Powel H, Litzenburger, Beate C
core   +1 more source

Novel tretinoin 0.05% lotion for the once-daily treatment of moderate-to-severe acne vulgaris in a preadolescent population. [PDF]

open access: yes, 2019
BackgroundAcne vulgaris (acne) is a common skin condition in children and adolescents. Efficacy of tretinoin is well documented in studies that included pediatric patients (12-18 years of age). With acne routinely presenting in younger patients, data are
Bhatt, Varsha   +4 more
core   +1 more source

Retinoid-binding proteins: mediators of retinoid action [PDF]

open access: yesBiochemical Journal, 2000
Active vitamin A metabolites, known as retinoids, are essential for multiple physiological processes, ranging from vision to embryonic development. These small hydrophobic compounds associate in vivo with soluble proteins that are present in a variety of cells and in particular extracellular compartments, and which bind different types of retinoids ...
openaire   +2 more sources

Dermatology [PDF]

open access: yes, 2004
Dermatology continues to develop at a steady pace. In the past few years there have been exciting advances in our understanding of skin structure and function in health and disease and progress in genetics, epidemiology, immunology, pharmacology and ...
Boffa, Michael J.
core   +1 more source

Revival of the Russian chemical industry during the Soviet period (1917–1927). Part 4

open access: yesРазработка и регистрация лекарственных средств, 2022
The fourth chapter presents V. N. Ipatiev's memoirs about the preparation and celebration of the 200th anniversary of the Russian Academy of Sciences and the next Mendeleev Congress.
K. S. Guzev
doaj  

Enhancement of Efficacy of Retinoids through Enhancing Retinoid-Induced RAR Activity and Inhibiting Hydroxylation of Retinoic Acid, and Its Clinical Efficacy on Photo-Aging

open access: yesPharmaceutics, 2022
Retinoids, one of the most robust bioactive materials, have been widely used to improve various dermatological and pathological conditions. The body has an endogenous mechanism that modulates the exogenous retinoid above physiological concentrations ...
Seongsu Kang   +4 more
doaj   +1 more source

Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate. [PDF]

open access: yes, 2017
The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL). Absorption of a photon isomerizes 11cRAL to all-trans-retinaldehyde (atRAL), briefly activating the pigment before it dissociates ...
Fain, Gordon L   +6 more
core   +1 more source

The Role of the Decrees of Peter the Great in the Formation and Development of Russian Pharmacy. Part 2

open access: yesРазработка и регистрация лекарственных средств, 2023
The second part of the article presents the next steps of Peter the Great to improve the functioning of the pharmacy service in Russia. To improve the management of the nascent pharmacy service, the Emperor established the Main Pharmacy in the ...
K. S. Guzev
doaj  

RPB4 and pathogenesis of diabetes [PDF]

open access: yes, 2007
Obesity is an important risk factor for a number of chronic diseases that impose a huge burden on individuals and society. Recently it has become clear that adipose tissue-secreted products may play a significant role in mediating many obesity-related ...
Kumar, Sudhesh   +1 more
core   +1 more source

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