Results 41 to 50 of about 83,475 (294)

Systemic treatment of seborrheic dermatitis with retinol palmitate

open access: yesVestnik Dermatologii i Venerologii, 2017
The goal of the study. Evaluating of the effectiveness of treatment of men with a diagnosis «Seborrheic dermatitis of the scalp» by the system using of retinol palmitate. Material and methods.
O. V. Kalinina   +3 more
doaj   +1 more source

Why Differentiation Therapy Sometimes Fails: Molecular Mechanisms of Resistance to Retinoids

open access: yesInternational Journal of Molecular Sciences, 2018
Retinoids represent a popular group of differentiation inducers that are successfully used in oncology for treatment of acute promyelocytic leukemia in adults and of neuroblastoma in children.
P. Chlapek   +4 more
semanticscholar   +1 more source

The Origin of Teratogenic Retinoids in Cyanobacteria

open access: yesToxins, 2022
Although information about the occurrence and distribution of retinoids in the environment is scarce, cyanobacterial water blooms have been identified as a significant source of these small molecules.
Luděk Sehnal   +5 more
doaj   +1 more source

Long-term safety and efficacy of trifarotene 50 μg/g cream, a first-in-class RAR-γ selective topical retinoid, in patients with moderate facial and truncal acne. [PDF]

open access: yes, 2020
BackgroundTreatment for both facial and truncal acne has not sufficiently been studied.ObjectivesTo evaluate the long-term safety and efficacy of trifarotene in both facial and truncal acne.MethodsIn a multicentre, open-label, 52-week study, patients ...
Ahmad, F   +11 more
core  

Traffic lights for retinoids in oncology: molecular markers of retinoid resistance and sensitivity and their use in the management of cancer differentiation therapy

open access: yesBMC Cancer, 2018
For decades, retinoids and their synthetic derivatives have been well established anticancer treatments due to their ability to regulate cell growth and induce cell differentiation and apoptosis. Many studies have reported the promising role of retinoids
Viera Dobrotkova   +4 more
semanticscholar   +1 more source

Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate. [PDF]

open access: yes, 2017
The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL). Absorption of a photon isomerizes 11cRAL to all-trans-retinaldehyde (atRAL), briefly activating the pigment before it dissociates ...
Fain, Gordon L   +6 more
core   +1 more source

Retinoids and rexinoids in cancer prevention: from laboratory to clinic.

open access: yesSeminars in Oncology, 2016
Early in the age of modern medicine the consequences of vitamin A deficiency drew attention to the fundamental link between retinoid-dependent homeostatic regulation and malignant hyperproliferative diseases.
I. Uray, E. Dmitrovsky, P. Brown
semanticscholar   +1 more source

Function annotation of hepatic retinoid x receptor α based on genome-wide DNA binding and transcriptome profiling. [PDF]

open access: yes, 2012
BackgroundRetinoid x receptor α (RXRα) is abundantly expressed in the liver and is essential for the function of other nuclear receptors. Using chromatin immunoprecipitation sequencing and mRNA profiling data generated from wild type and RXRα-null mouse ...
Fang, Jianwen   +5 more
core   +6 more sources

Targeted therapy for breast cancer prevention. [PDF]

open access: yes, 2013
With a better understanding of the etiology of breast cancer, molecularly targeted drugs have been developed and are being testing for the treatment and prevention of breast cancer.
Brown, Powel H   +2 more
core   +2 more sources

Retinoids and Retinal Diseases.

open access: yesAnnual Review of Vision Science, 2016
Recent progress in molecular understanding of the retinoid cycle in mammalian retina stems from painstaking biochemical reconstitution studies supported by natural or engineered animal models with known genetic lesions and studies of humans with specific
P. Kiser, K. Palczewski
semanticscholar   +1 more source

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