Systemic treatment of seborrheic dermatitis with retinol palmitate
The goal of the study. Evaluating of the effectiveness of treatment of men with a diagnosis «Seborrheic dermatitis of the scalp» by the system using of retinol palmitate. Material and methods.
O. V. Kalinina+3 more
doaj +1 more source
Why Differentiation Therapy Sometimes Fails: Molecular Mechanisms of Resistance to Retinoids
Retinoids represent a popular group of differentiation inducers that are successfully used in oncology for treatment of acute promyelocytic leukemia in adults and of neuroblastoma in children.
P. Chlapek+4 more
semanticscholar +1 more source
The Origin of Teratogenic Retinoids in Cyanobacteria
Although information about the occurrence and distribution of retinoids in the environment is scarce, cyanobacterial water blooms have been identified as a significant source of these small molecules.
Luděk Sehnal+5 more
doaj +1 more source
Long-term safety and efficacy of trifarotene 50 μg/g cream, a first-in-class RAR-γ selective topical retinoid, in patients with moderate facial and truncal acne. [PDF]
BackgroundTreatment for both facial and truncal acne has not sufficiently been studied.ObjectivesTo evaluate the long-term safety and efficacy of trifarotene in both facial and truncal acne.MethodsIn a multicentre, open-label, 52-week study, patients ...
Ahmad, F+11 more
core
For decades, retinoids and their synthetic derivatives have been well established anticancer treatments due to their ability to regulate cell growth and induce cell differentiation and apoptosis. Many studies have reported the promising role of retinoids
Viera Dobrotkova+4 more
semanticscholar +1 more source
Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate. [PDF]
The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL). Absorption of a photon isomerizes 11cRAL to all-trans-retinaldehyde (atRAL), briefly activating the pigment before it dissociates ...
Fain, Gordon L+6 more
core +1 more source
Retinoids and rexinoids in cancer prevention: from laboratory to clinic.
Early in the age of modern medicine the consequences of vitamin A deficiency drew attention to the fundamental link between retinoid-dependent homeostatic regulation and malignant hyperproliferative diseases.
I. Uray, E. Dmitrovsky, P. Brown
semanticscholar +1 more source
Function annotation of hepatic retinoid x receptor α based on genome-wide DNA binding and transcriptome profiling. [PDF]
BackgroundRetinoid x receptor α (RXRα) is abundantly expressed in the liver and is essential for the function of other nuclear receptors. Using chromatin immunoprecipitation sequencing and mRNA profiling data generated from wild type and RXRα-null mouse ...
Fang, Jianwen+5 more
core +6 more sources
Targeted therapy for breast cancer prevention. [PDF]
With a better understanding of the etiology of breast cancer, molecularly targeted drugs have been developed and are being testing for the treatment and prevention of breast cancer.
Brown, Powel H+2 more
core +2 more sources
Retinoids and Retinal Diseases.
Recent progress in molecular understanding of the retinoid cycle in mammalian retina stems from painstaking biochemical reconstitution studies supported by natural or engineered animal models with known genetic lesions and studies of humans with specific
P. Kiser, K. Palczewski
semanticscholar +1 more source