Results 71 to 80 of about 55,482 (284)

Mapping molluscan endocrinology: a systematic and critical appraisal

Biological Reviews, EarlyView.
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis, Thomas H. Miller, Olwenn V. Martin, Alice Baynes   +3 more
wiley   +1 more source

Solution structure of a repeated unit of the ABA-1 nematode polyprotein allergen of ascaris reveals a novel fold and two discrete lipid-binding sites [PDF]

, 2011
Parasitic nematode worms cause serious health problems in humans and other animals. They can induce allergic-type immune responses, which can be harmful but may at the same time protect against the infections. Allergens are proteins that trigger allergic
A Cooper, A Garofalo, Alan Cooper, Alejandro Buschiazzo, AT Brunger, BB Kragelund, Brian O. Smith, BS Mei, C Britton, C Lucke, C McSharry, CB Poole, CB Poole, CB Poole, DS Wishart, DS Wishart, Dušan Uhrín, ED Laue, GJ Kleywegt, Graeme Ball, GW Han, HJ Sass, HJ Spence, HS Lee, I Vercauteren, J Culpepper, J Dundas, J Moore, J Plenefisch, JA Rothnagel, JC Kader, JD Turner, JP Linge, JP Linge, JR Allison, JT Jones, JT Vivian, KH Mok, Krystyna Bromek, L Holm, L Kuang, L McDermott, LA Tomlinson, LE Kay, M Blaxter, M Furuhashi, M Nilges, M Ottiger, M Piotto, M Zweckstetter, M Zweckstetter, Malcolm W. Kennedy, MR Hansen, MS Cheung, MW Kennedy, MW Kennedy, MW Kennedy, MW Kennedy, MW Kennedy, MW Kennedy, MW Kennedy, MW Kennedy, MW Kennedy, N Acevedo, N Tjandra, NA Farrow, NAG Meenan, NAG Meenan, Nicola A. G. Meenan, P Ovaere, P Permi, P Permi, PJ Kraulis, R Jordanova, R Jordanova, RA Laskowski, RB Presland, RID Wakefield, RM Maizels, RW Alston, S Basavaraju, S Bennuru, S Curry, S Tweedie, WA Paxton, WF Vranken, Y Xia, YP Tong   +87 more
core   +7 more sources

The endocannabinoid system regulates both ependymoglial and neuronal cell responses to a tail amputation in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Michael Tolentino, Sarah E. Walker, Gaynor E. Spencer, Robert Carlone   +3 more
wiley   +1 more source

Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function [PDF]

, 2018
Visual function in vertebrates critically depends on the continuous regeneration of visual pigments in rod and cone photoreceptors. RPE65 is a well-established retinoid isomerase in the pigment epithelium that regenerates rhodopsin during the rod visual ...
Angueyra, Juan M, Badiee, Mohsen, Kefalov, Vladimir J, Kinoshita, Junzo, Kiser, Philip D, Kolesnikov, Alexander V, Li, Wei, Palczewski, Krzysztof, Peachey, Neal S, Sharma, Aditya, Tochtrop, Gregory P, Zhang, Jianye   +11 more
core   +1 more source

Clock gene dysregulation in epilepsy: A systematic review

Epilepsia Open, EarlyView.
Abstract Objective Epileptic seizures show a rhythmic pattern, being more frequent at particular times of the day (e.g., only occurring during sleep), suggesting a role of the circadian rhythm. Clock genes regulate the circadian rhythm and might be involved in the pathophysiology of epilepsy.
Guilherme Fernandes‐Campos, Arjune Sen, Francesca Panin, Krithika Sundararaman   +3 more
wiley   +1 more source

NRF2 regulates HER1 signaling pathway to modulate the sensitivity of ovarian cancer cells to lapatinib and erlotinib [PDF]

, 2017
NF-E2-related factor 2 (NRF2) regulates the transcription of a battery of metabolic and cytoprotective genes. NRF2 and epidermal growth factor receptors (EGFRs/HERs) are regulators of cellular proliferation and determinants of cancer initiation and ...
Bown, James L., Deeni, Yusuf Y., Hamza Kankia, Ibrahim, Khalil, Hilal S., Langdon, Simon P., Moult, Peter R.   +5 more
core   +6 more sources

ABOUT GALEN (PAGES OF LIFE AND TRAITS OF THE PERSON IN THE ASSESSMENT OF THE DESCENDANTS)

Разработка и регистрация лекарственных средств, 2019
The paper presents the pages of life and some character traits of the Roman physician Galen. The source of information is the materials published in domestic and foreign literature.
K. S. Guzev
doaj  

GALEN AND HIS KNOWLEDGE IN THE FIELD OF PHARMACOLOGY

Разработка и регистрация лекарственных средств, 2019
The paper presents the literature data on the knowledge K. Galen in pharmacology. The source of information is the materials published in domestic and foreign literature.
K. S. Guzev
doaj  

GALEN AND KNOWLEDGE OF PHARMACY

Разработка и регистрация лекарственных средств, 2019
The paper presents the literature data on the occurrence of the term "Galenic medicines" and the contribution of K. Galen in the formation and development of pharmacy.
K. S. Guzev
doaj  

The Impact of Methotrexate on Cardiovascular Outcomes in Psoriasis: A Systematic Review and Meta‐Analysis

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Psoriasis is a chronic immune‐mediated inflammatory disease with a global prevalence of 2%–3% and 1.3% in Brazil. It is associated with comorbidities such as obesity, hypertension, and diabetes, all of which contribute to increased cardiovascular risk due to systemic inflammation and endothelial dysfunction.
Tiago A. S. Costa, Sheila T. K. Medorima, Renata F. Magalhães   +2 more
wiley   +1 more source