PLoS ONE, 2019 Although the administration of retinoids represents an important part of treatment for children suffering from high-risk neuroblastomas, approximately 50% of these patients do not respond to this therapy or develop resistance to retinoids during ...
Viera Dobrotkova +6 more
doaj +1 more source
Retinoic acid induces the differentiation of B cell hybridomas from patients with common variable immunodeficiency. [PDF]
, 1988 Human-human B cell hybridomas constructed from B lymphocytes of common variable immunodeficiency (CVI) patients and the nonsecreting cell line WIL2/729 HF consistently secrete low levels of Ig and appear to retain a defect characteristic of the CVI ...
Adelman, DC +5 more
core
Hyperhidrosis: problems and solutions [PDF]
Vestnik Dermatologii i VenerologiiThe functional role of sweating is not limited only to thermoregulation and excretion. There are other functions of it — the ability to enhance and maintain hydration and barrier function of the skin.
Stanislava Yu. Petrova +2 more
doaj +1 more source
Acquired epidermodysplasia verruciformis due to multiple and unusual HPV infection among vertically-infected, HIV-positive adolescents in Zimbabwe. [PDF]
, 2012 BACKGROUND: We have previously described the presentation of epidermodysplasia verruciformis (EV)-like eruptions in almost a quarter of hospitalized adolescents with vertically-acquired human immunodeficiency virus (HIV) infection in Harare, Zimbabwe, a ...
Bunker, CB +13 more
core +3 more sources
Разработка и регистрация лекарственных средств, 2019 The paper presents information about F.B. Schwabe and N. Zaklin, entrepreneurs of the late 19th and early 20th centuries who, through their labor and ingenuity, created the material and technical base that provided the development of various branches of ...
K. S. Guzev
doaj
G2A Attenuates Propionibacterium acnes Induction of Inflammatory Cytokines in Human Monocytes. [PDF]
, 2017 Background:Acne vulgaris is a disease of the pilosebaceous unit characterized by increased sebum production, hyperkeratinization, and immune responses to Propionibacterium acnes (PA).
Agak, George W +10 more
core +1 more source
ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion [PDF]
, 2016 Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a dismal survival rate. Persistent activation of pancreatic stellate cells (PSCs) can perturb the biomechanical homoeostasis of the tumour microenvironment to favour cancer ...
Attwood, S +10 more
core +1 more source
Retinoids activate the irritant receptor TRPV1 and produce sensory hypersensitivity.
Journal of Clinical Investigation, 2013 Retinoids are structurally related derivatives of vitamin A and are required for normal vision as well as cell proliferation and differentiation. Clinically, retinoids are effective in treating many skin disorders and cancers.
Shijin Yin +11 more
semanticscholar +1 more source
Solution structure of a repeated unit of the ABA-1 nematode polyprotein allergen of ascaris reveals a novel fold and two discrete lipid-binding sites [PDF]
, 2011 Parasitic nematode worms cause serious health problems in humans and other animals. They can induce allergic-type immune responses, which can be harmful but may at the same time protect against the infections. Allergens are proteins that trigger allergic
A Cooper +87 more
core +7 more sources
Разработка и регистрация лекарственных средств, 2019 The paper presents literature data on the history of the finding of Ebers' papyrus and its further study. Its contents are disclosed: the diseases that were known to ancient doctors are listed, the list of medicines used by Egyptian doctors is presented,
K. S. Guzev
doaj