Results 31 to 40 of about 666,471 (318)

Reverse genetics for mammalian reovirus [PDF]

open access: greenMethods, 2011
Mammalian orthoreoviruses (reoviruses) are highly tractable models for studies of viral replication and pathogenesis. The versatility of reovirus as an experimental model has been enhanced by development of a plasmid-based reverse genetics system. Infectious reovirus can be recovered from cells transfected with plasmids encoding cDNAs of each reovirus ...
Karl W. Boehme   +3 more
openalex   +4 more sources

Advantages, disadvantages and research progress on strategies for screening and identifying functional genes [PDF]

open access: yesJichu yixue yu linchuang, 2022
The screening and identification of functional genes is a key step to deeply understand various biological phenotypes. Forward genetics including traditional genetics, genome-wide association analysis, the comparison of gene expression profiles and ...
LIU Xu, CHANG De, WANG Jun-feng
doaj   +1 more source

The human Cranio Facial Development Protein 1 (Cfdp1) gene encodes a protein required for the maintenance of higher-order chromatin organization [PDF]

open access: yes, 2017
The human Cranio Facial Development Protein 1 (Cfdp1) gene maps to chromosome 16q22.2-q22.3 and encodes the CFDP1 protein, which belongs to the evolutionarily conserved Bucentaur (BCNT) family.
Atterrato, Maria Teresa   +5 more
core   +3 more sources

Reverse genetics-derived cattle H5N1 virus from Clade 2.3.4.4b shows enhanced systemic infectivity and pathogenicity than an older Clade 1 H5N1 virus in BALB/c mice. [PDF]

open access: goldEmerg Microbes Infect
Xiao N   +17 more
europepmc   +3 more sources

Rewriting Human History and Empowering Indigenous Communities with Genome Editing Tools. [PDF]

open access: yes, 2020
Appropriate empirical-based evidence and detailed theoretical considerations should be used for evolutionary explanations of phenotypic variation observed in the field of human population genetics (especially Indigenous populations). Investigators within
Fox, Keolu   +2 more
core   +2 more sources

Cytokines, reverse genetics and anti-cytokine therapy

open access: yesБюллетень сибирской медицины, 2019
Cytokines comprise the molecular language of communication between the cells, which is needed to maintain the homeostatic functions of the body (including the immune system) and mediate various diseases.
M. S. Drutskaya   +9 more
doaj   +1 more source

Reverse genetics of rotavirus [PDF]

open access: yesProceedings of the National Academy of Sciences, 2017
The genetics of viruses are determined by mutations of their nucleic acid. Mutations can occur spontaneously or be produced by physical or chemical means: for example, the application of different temperatures or mutagens (such as hydroxylamine, nitrous acid, or alkylating agents) that alter the nucleic acid.
openaire   +2 more sources

Reverse Genetics for Double-Stranded RNA Viruses

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2009
Resumen en inglès, ver archivo ...
H. Attoui   +3 more
doaj   +1 more source

Modern approaches to production of safe and effective genetically modified rabies vaccines for animals

open access: yesВетеринария сегодня, 2023
Rabies is a dangerous zoonoticdisease that affects the central nervous system, causes encephalomyelitis and paralyses and Is almost invariably fatal.
M. I. Doronin   +6 more
doaj   +1 more source

Establishment of a Simple and Efficient Reverse Genetics System for Canine Adenoviruses Using Bacterial Artificial Chromosomes

open access: yesViruses, 2020
Canine adenoviruses (CAdVs) are divided into pathotypes CAdV1 and CAdV2, which cause infectious hepatitis and laryngotracheitis in canid animals, respectively.
Hiromichi Matsugo   +6 more
doaj   +1 more source

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