Results 41 to 50 of about 2,173,029 (360)
A simple reverse genetics method to generate recombinant coronaviruses
EMBO Reports, 2021 Engineering recombinant viruses is a pre‐eminent tool for deciphering the biology of emerging viral pathogens such as the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).
J. Mélade +9 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Respiratory syncytial virus (RSV) remains a major cause of severe respiratory disease worldwide in children, older individuals, and immunosuppressed patients. An increasing understanding of this disease burden together with the absence of an
Wendy K. Jo +13 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Coltiviruses, including important pathogens such as Colorado tick fever virus in humans, have a genome comprising 12 segments of double-stranded (ds) RNA.
Ryotaro Nouda +9 more
semanticscholar +1 more source
FAST Proteins: Development and Use of Reverse Genetics Systems for Reoviridae Viruses.
Annual Review of Virology, 2021 Reverse genetics systems for viruses, the technology used to generate gene-engineered recombinant viruses from artificial genes, enable the study of the roles of the individual nucleotides and amino acids of viral genes and proteins in infectivity ...
Y. Kanai, Takeshi Kobayashi
semanticscholar +1 more source
Review on forward and reverse genetics in plant breeding
, 2021 Forward genetics is the identification and characterization of the gene that is responsible for the mutant phenotype.
Endalkachew Aklilu
semanticscholar +1 more source
Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host [PDF]
, 2013 Schmallenberg virus (SBV) is an emerging orthobunyavirus of ruminants associated with outbreaks of congenital malformations in aborted and stillborn animals.
A Bridgen +73 more
core +8 more sources
Reverse Genetics System for Rabbit vesivirus
Frontiers in Microbiology, 2020 Most caliciviruses are refractory to replication in cell culture and only a few members of the family propagate in vitro. Rabbit vesivirus (RaV) is unique due to its ability to grow to high titers in several animal and human cell lines.
Ángel L. Álvarez +8 more
doaj +1 more source
A Reverse Genetics System for Zika Virus Based on a Simple Molecular Cloning Strategy [PDF]
Viruses, 2018 The Zika virus (ZIKV) has recently attracted major research interest as infection was unexpectedly associated with neurological manifestations in developing foetuses and with Guillain-Barré syndrome in infected adults.
Maximilian Münster +6 more
openalex +2 more sources
Optimized properties of live vaccine influenza reassortant strains obtained by reverse genetics
Инфекция и иммунитет, 2023 Classical reassortment in developing chicken eggs is a well-established technique for obtaining LAIV strains. Naturally generated reassortant vaccine strains are characterized by high reproductive capacity, genetically stable characteristics of ...
N. V. Larionova +4 more
doaj +1 more source
Plant Cellular and Molecular Biotechnology: Following Mariotti's Steps [PDF]
, 2019 This review is dedicated to the memory of Prof. Domenico Mariotti, who significantly contributed to establishing the Italian research community in Agricultural Genetics and carried out the first experiments of Agrobacterium-mediated plant genetic ...
Caretto, Sofia +11 more
core +1 more source