Results 41 to 50 of about 7,209,798 (282)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Heat recovery from sulfuric acid plants for seawater desalination using RO and MED systems
Applied Water Science, 2020 Conforming to the factor characteristics of electricity–water cogeneration power plants, an improved multieffect desalination (MED) and reverse osmosis (RO) are the most current techniques for seawater desalination.
D. Saifaoui +4 more
doaj +1 more source
A 100‐V trench power MOSFET with taper‐shielded gate and non‐uniform drift region doping profile
IET Power Electronics, 2023 A 100‐V Taper‐Shielded trench Gate (TSG) power metal‐oxide‐semiconductor field‐effect transistor (MOSFET) with superior figure‐of‐merit (FOM) is proposed and investigated in this paper.
Gaoqaing Deng +5 more
doaj +1 more source
Information, 2023 Evaluation and selection of a third-party reverse logistics provider (3PRLP) is an important tool for enterprises to improve the level of reverse logistics management.
Changlu Zhang, Liqian Tang, Jian Zhang
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Students Voicing Collegiate Recovery [PDF]
, 2018 Young adults increasingly enter college with substance use addiction. Some may achieve recovery before setting their foot on a college campus whereas others during their college years.
Cravalho, Danielle, Cheney, Ann M
core +1 more source
Recovery ... reporting overview; Connecticut recovery; CT recovery ... progress
, 2011 Updated quarterly; Began in 2009.; Title from home page last modified 10/29/2009 (viewed Oct. 29, 2009).; At head of title: State of Connecticut.; "On October 1, state agencies that have received Recovery Act funds began reporting to the federal ...
core +3 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Energies, 2020 In this study, a novel 4H-SiC double-trench metal-oxide semiconductor field-effect transistor (MOSFET) with a side wall heterojunction diode is proposed and investigated by conducting numerical technology computer-aided design simulations.
Junghun Kim, Kwangsoo Kim
doaj +1 more source