Results 221 to 230 of about 382,156 (284)

In-silico identification of phytochemical compounds from various medicinal plants as potent HIV-1 non-nucleoside reverse transcriptase inhibitors utilizing molecular docking and molecular dynamics simulations. [PDF]

Biol Methods Protoc
Danladi S, Adeniyi AA, Sani ZI, Temitope A.   +3 more
europepmc   +1 more source

Development of Reverse Transcriptase Recombinase Polymerase Amplification Combined with Lateral Flow Dipstick for Rapid Detection of Tilapia Lake Virus (TiLV): Pilot Study. [PDF]

Vet Sci
Srivorakul S, Guntawang T, Sittisak T, Gordsueb T, Boonsri K, Khattiya R, Sthitmatee N, Pringproa K.   +7 more
europepmc   +1 more source

Reverse Transcriptase Inhibitor [PDF]

, 2020
openaire   +1 more source

Macrophage Tropism of HIV-1 Depends on Efficient Cellular dNTP Utilization by Reverse Transcriptase

, 2004
Tracy L. Diamond, Mikhail Roshal, Varuni K. Jamburuthugoda, Holly M. Reynolds, Aaron R. Merriam, Kwi Y. Lee, Mini Balakrishnan, Robert A. Bambara, Vicente Planelles, Stephen Dewhurst, Baek Kim   +10 more
openalex   +1 more source

Role of COL1A1 and CD44 in Modulating JAK1/STAT3‐Mediated Autophagy for Spinal Cord Injury Recovery

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Spinal cord injury (SCI) is a severe trauma to the central nervous system that often leads to motor and sensory dysfunction in patients, severely affecting their quality of life. Autophagy plays a role in the pathological process of SCI, but the specific mechanism of autophagy in this case is unknown.
Chun‐Lei Li, Qian Zhang, Li Fang, Ling‐Yun Zhou   +3 more
wiley   +1 more source

Acquired HIV-1 drug resistance to reverse transcriptase and protease inhibitors among people failing antiretroviral therapy in Cameroon and implications for future treatment options. [PDF]

AIDS Res Ther
Fokam J, Anim-Keng TT, Pokam BT, Chenwi CA, Ka'e AC, Semengue ENJ, Beloumou Angong OEG, Takou D, Nka AD, Djupsa S, Etame NK, Molimbou E, Ajeh R, Bissek AZ, Colizzi V, Perno CF, Halle-Ekane GE, Ndembi N, Ndjolo A.   +18 more
europepmc   +1 more source

Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review

Medicine Bulletin, EarlyView.
ABSTRACT Aging is orchestrated by interconnected hallmarks such as genomic instability, mitochondrial dysfunction, cellular senescence, and disrupted intercellular communication, which collectively drive chronic disease progression. Recent advances have expanded therapeutic opportunities to include pharmacological agents, gene and epigenome editing ...
Yundong Peng, Rui Li, Huan Li, Jun Zhou, Xuanshi Liu, Guilherme Valente, Tatiana de Campos Melo, Sifan Chen, Lei Gu   +8 more
wiley   +1 more source

Lactic acid produced by optimal vaginal Lactobacillus spp. potently and specifically inactivates HIV-1 in vitro by targeting the viral RNA genome and reverse transcriptase. [PDF]

PLoS Pathog
Aldunate M, Tyssen D, Johnson A, Latham CF, Ellenberg P, Cowieson N, Hayward JA, Center RJ, Ramsland PA, Hearps AC, Tachedjian G.   +10 more
europepmc   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications

ChemistryOpen, EarlyView.
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali, Atif Ali Khan Khalil, Muhammad Saeed Akhtar, Adnan Amin, Wajid Zaman   +4 more
wiley   +1 more source