Results 231 to 240 of about 1,758,180 (373)

Inhibition of long interspersed nuclear element-1 by nucleoside reverse transcriptase inhibitors attenuates vascular calcification. [PDF]

Signal Transduct Target Ther
Ma J, He D, Zhang M, Zhou Z, Cheng J, Huang A, Lian Y, Shi Y, Xie C, Guan Z, Zhang Z, Xie C, Zhang T, Huang H.   +13 more
europepmc   +1 more source

Light Metabolically Reprograms CD8+ T Cells to Potentiate STING‐Driven Tumor Eradication and Prevent Metastasis

Advanced Science, EarlyView.
Low‐level light (LLL) rejuvenates exhausted CD8+ T cells, boosting STING‐driven tumor eradication and prevents metastasis. NanoSTING@Mn enhances CD8+ T cells infiltration while LLL restores its function expanding to progenitor‐exhausted cells. These cells form central memory T cells in lymphoid organs. Intranasal nanoSTING@Mn redirects antitumor CD8+ T
Asmita Banstola, Shilin Gao, Zhengkung Zhang, Yan Dong, Prabhat Upadhyay, Quanwei Zhang, Yongli Li, Zuan‐Tao Lin, Zhilong Wang, Mei X. Wu   +9 more
wiley   +1 more source

Boron deficiency responses in maize (Zea mays L.) roots

Journal of Plant Nutrition and Soil Science, EarlyView., 2023
Abstract Background Boron (B) is an essential micronutrient for plants. Dicot plants respond to insufficient B supply by altering root architecture and root hair growth. How root systems of rather low‐B demanding monocot species such as maize (Zea mays L.) respond to B deficiency in terra has not been experimentally resolved, yet.
Manuela Désirée Bienert, Astrid Junker, Michael Melzer, Thomas Altmann, Nicolaus von Wirén, Gerd Patrick Bienert   +5 more
wiley   +1 more source

Reverse transcriptase activity in psoriatic lesions: effects of reverse transcriptase inhibitors on keratinocyte proliferation and differentiation

Retrovirology, 2009
Bonté Frédéric, Dumas Marc, Tesniere Anne, Molès Jean-Pierre, Guilhou J-J   +4 more
doaj   +1 more source

Characterization of LTR Retrotransposon Reverse Transcriptase in <i>Tamarix chinensis</i> L. and Activity Analysis Under Salt and Alkali Stresses. [PDF]

Genes (Basel)
Wang L, Li B, Wang Y, Wang S, Zhang M, Li M, Zheng T, Wang H.   +7 more
europepmc   +1 more source

Osmotically Tunable Microdroplets Enable Amplification‐Free CRISPR Detection of Gene Doping

Advanced Science, EarlyView.
A novel amplification‐free clustered regularly interspaced short palindromic repeats/CRISPR‐associated protein (CRISPR/Cas) 12a assay is integrated with osmotically shrinkable double emulsion droplets for the rapid and ultrasensitive detection of gene doping.
Jihun Han, Reya Ganguly, Joon‐Yeop Yi, Hyewon Yun, So‐Yeon Jung, Changmin Sung, Chang‐Soo Lee   +6 more
wiley   +1 more source

MK-8527 is a novel inhibitor of HIV-1 reverse transcriptase translocation with potential for extended-duration dosing. [PDF]

PLoS Biol
Raheem IT, Girijavallabhan V, Fillgrove KL, Goh SL, Bahnck-Teets C, Huang Q, Li F, Wan BL, O'Donnell GT, Patteson JB, Cilento ME, Bennet A, Hayes RP, Tummala S, McHale C, Wiltsie J, Ellis J, Asante-Appiah E, Hazuda DJ, Hale J, Grobler JA, Xu M, Diamond TL, Lai MT.   +23 more
europepmc   +1 more source

Reverse Transcriptase

IUPAC Standards Online, 2019
J. Labuda, R. Bowater, M. Fojta, G. Gauglitz, Z. Glatz, I. Hapala, J. Havliš, F. Kilár, Anikó Kilár, Lenka Malinovská, Heli M. M. Sirén, P. Skládal, F. Torta, M. Valachovič, M. Wimmerová, Z. Zdráhal, D. B. Hibbert   +16 more
semanticscholar   +1 more source

RNAi Regulator C3PO Promotes Arbovirus Infection in Insect Vectors

Advanced Science, EarlyView.
RNA interference (RNAi) is vital for eukaryotes to defend against virus infection. The C3PO complex takes part in RNAi but its role in regulating viral infection remains unclear. This work finds that insect C3PO facilitates arbovirus replication by degrading precursors of miRNAs, especially miR‐971‐3p.
Yan Xiao, Tianyu Guan, Qianfeng Xia, Chen Chen, Qian Wang, Lan Luo, Hong Lu, Feng Cui   +7 more
wiley   +1 more source

Telomerase reverse transcriptase degradation via a rationally designed covalent proteolysis targeting chimera. [PDF]

Bioorg Med Chem Lett
Frost GB, Liu Y, Kron SJ, Scheidt KA.
europepmc   +1 more source