Results 11 to 20 of about 562,468 (202)
Vaccines, 2023 Reverse vaccinology is a powerful tool that was recently used to develop vaccines starting from a pathogen genome. Some bacterial infections have the necessity to be prevented then treated.
Mario Cocorullo +2 more
doaj +3 more sources
Vaccines, Reverse Vaccinology, and Bacterial Pathogenesis [PDF]
Cold Spring Harbor Perspectives in Medicine, 2013 Advances in genomics and innovative strategies such as reverse vaccinology have changed the concepts and approaches to vaccine candidate selection and design. Genome mining and blind selection of novel antigens provide a novel route to investigate the mechanisms that underpin pathogenesis.
Delany, Isabel +2 more
openaire +4 more sources
Developing vaccines in the era of genomics: a decade of reverse vaccinology [PDF]
Clinical Microbiology and Infection, 2012 Vaccines have a significant impact on public health, and vaccinology in the era of genomics is taking advantage of new technologies to tackle diseases for which vaccine development has so far been unsuccessful. Almost all existing vaccines were developed based on traditional vaccinology methods, which relied on empirical screening of a few candidates ...
Seib, KL, Zhao, X, Rappuoli, R
openaire +5 more sources
Generative AI and large language models: A new frontier in reverse vaccinology [PDF]
Informatics in Medicine UnlockedReverse vaccinology is an emerging concept in the field of vaccine development as it facilitates the identification of potential vaccine candidates.
Kadhim Hayawi +3 more
doaj +2 more sources
Global research trends in reverse vaccinology from 2000 to 2021: A bibliometric analysis
Informatics in Medicine Unlocked, 2023 Reverse vaccinology (RV) is a promising computational approach for expediting vaccine development by screening pathogen proteomes for protective antigens. This bibliometric analysis examined RV research from 2000 to 2021.
Zakia Salod, Ozayr Mahomed
doaj +2 more sources
Identification of Novel Vaccine Candidates against Campylobacter through Reverse Vaccinology
Journal of Immunology Research, 2016 Campylobacteriosis is the most prevalent bacterial foodborne gastroenteritis affecting humans in the European Union. Human cases are mainly due to Campylobacter jejuni or Campylobacter coli, and contamination is associated with the handling and/or ...
Marine Meunier +5 more
doaj +2 more sources
Review on Approaches to Reverse Vaccinology Against Dangerous Pathogens in Animals [PDF]
, 2023 Vaccines have been recognized as major and effective tools For controlling disease impact, vaccinology is a field with great opportunity. Contribution of vaccines towards societal development by improvement of health status and increasing life-expectancy
Mulatu, Henok
core +4 more sources
Application of In-Silico Reverse Vaccinology for Designing Multi-Epitope Vaccine Against Coronavirus [PDF]
, 2020 In absence of any specific medication or vaccine till now, experimentation has reached new heights. With lockdown imposed in almost every country and huge economic losses the search for a suitable vaccine has still been unsuccessful.
Dr. Shubhangi, Dange, Kumar, Sharp
core +1 more source
Veterinary Sciences, 2021 Porcine circovirus 2 (PCV2), considered one of the most globally important porcine pathogens, causes postweaning multisystemic wasting syndrome (PMWS). This virus is localized in the mitochondria in pigs with PMWS. Here, we identified, for the first time,
Wanting Yu +9 more
doaj +1 more source
Porcine Parvovirus 7: Evolutionary Dynamics and Identification of Epitopes toward Vaccine Design
Vaccines, 2020 Porcine parvovirus 7 (PPV7) belonging to the genus Chapparvovirus in the family Parvoviridae, has been identified in the USA, Sweden, Poland, China, South Korea and Brazil.
Dongliang Wang +3 more
doaj +1 more source