Results 101 to 110 of about 8,159 (227)

Nanog dynamics in mouse embryonic stem cells [PDF]

, 2017
Mouse embryonic stem cells (mESCs), derived from the inner cell mass of the blastocyst, are pluripotent stem cells having self-renewal capability and the potential of differentiating into every cell type under the appropriate culture conditions.
Marucci, Lucia
core   +4 more sources

G Protein‐Coupled Receptor Signaling: Implications and Therapeutic Development Advances in Cancers

MedComm, Volume 6, Issue 10, October 2025.
G protein‐coupled receptors (GPCRs) are the dynamic protein family in the human genome. GPCR dysregulation aids in the advancement of cancer through increased migration, survival, and proliferation. Novel treatments that target GPCR signaling include orthosteric ligands, biased receptor mutants, PROTACs, and antibody–drug conjugates.
Inamu Rashid Khan, Sana Khurshid, Saud Almawash, Rakesh Kumar, Ammira S. Al‐Shabeeb Akil, Ajaz A. Bhat, Muzafar A. Macha   +6 more
wiley   +1 more source

Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor [PDF]

, 2013
Self-renewal of pluripotent mouse embryonic stem (ES) cells is sustained by the cytokine leukaemia inhibitory factor (LIF) acting through the transcription factor Stat3.
Bertone, P, Martello, G, Smith, A
core   +1 more source

Genome‐wide association study uncovers a novel gene responsible for rice seedling submergence tolerance

Plant Biotechnology Journal, Volume 23, Issue 9, Page 4092-4108, September 2025.
Summary Submergence tolerance is crucial for the direct seeding of rice, yet long‐term domestication and breeding have inadvertently reduced the adaptability of cultivated rice to submergence stress. Here, we identify a nucleic acid excision repair protein‐encoding gene qSHS5 as an essential regulator of seedling height under submergence through a ...
Xueli Lu, Long Yang, Lan Shen, Chengfang Zhan, Liping Dai, Linzhou Huang, Qiang Zhang, Yunxia Fang, Deyong Ren, Li Zhu, Jiang Hu, Zhenyu Gao, Guangheng Zhang, Yongjun Lin, Dali Zeng, Dawei Xue, Qian Qian, Qing Li   +17 more
wiley   +1 more source

The role of vitamin C in the gene expression of oxidative stress markers in fibroblasts from burn patients [PDF]

Acta Cirúrgica Brasileira, 2018
Purpose: To assess the action of vitamin C on the expression of 84 oxidative stress related-genes in cultured skin fibroblasts from burn patients. Methods: Skin samples were obtained from ten burn patients.
Jessica Bonucci, Alfredo Gragnani, Marcelo Moraes Trincado, Victor Vincentin, Silvana Aparecida Alves Correa, Lydia Masako Ferreira   +5 more
doaj   +1 more source

Study of cutting force and surface roughness on drilling stainless steel 316L under various coolant condition [PDF]

, 2018
Drilling is the metal cutting process that are widely used in industrial sector such as in aerospace, automotive and manufacturing to produce a various of durable parts.
Chong, Y. L., Hamsah, A.A., Kamdani, K., Rafai, N.H., Rahim, M.Z., Wong, C.K.   +5 more
core   +1 more source

Advances in the Study of Pluripotent Stem Cells in Livestock

Cell Proliferation, Volume 58, Issue 8, August 2025.
Livestock pluripotent stem cells include embryonic stem cells (ESCs) isolated from the inner cell mass of blastocysts and induced pluripotent stem cells (iPSCs) derived from somatic cell reprogramming. They hold significant potential for applications in livestock breed improvement, rapid propagation, human disease modelling and human organ ...
Xinyi Zhou, Chen Gao, Wenxuan Zhao, Xinhua Wei, Dawei Yu, Huiying Zou, Weihua Du   +6 more
wiley   +1 more source

Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration

Nature Communications, 2016
The small GTPase Rac1 regulates various cellular processes, including cell migration. However, Rac1 can have opposing migratory effects. Here the authors show that two guanine nucleotide exchange factors, Tiam1 and P-Rex1, differentially regulate the ...
Hadir Marei, Alejandro Carpy, Anna Woroniuk, Claire Vennin, Gavin White, Paul Timpson, Boris Macek, Angeliki Malliri   +7 more
doaj   +1 more source

Corneal Cell Matrix‐Conditioned Amniotic Membrane with Improved Biochemical Properties and Corneal Wound Healing Potential: An In Vitro and In Vivo Study

Macromolecular Materials and Engineering, Volume 310, Issue 6, June 2025.
In this research, the amniotic membrane is sought to be enhanced biologically by treating it with primary cultured corneal cells. The findings indicate that amniotic membranes conditioned with limbal stem cells serve as an effective wound dressing that mimics corneal tissue, offering better cell adhesion, and healing properties, paving the way for ...
Zeinab Nokhbedehghan, Zahra Esmaeili, Seyed‐Hashem Daryabari, Hossein Aghamollaei, Sara Simorgh, Jila Majidi, Sanaz Alizadeh, Sadjad Khosravimelal, Narendra Pal Singh Chauhan, Hajar Nasiri, Mazaher Gholipourmalekabadi   +10 more
wiley   +1 more source

A Systematic Targeted Genetic Screen Identifies Proteins Involved in Cytoadherence of the Malaria Parasite P. falciparum

Molecular Microbiology, Volume 123, Issue 4, Page 330-343, April 2025.
In silico workflow for selection of genes targeted in this study. We have identified a number of proteins involved in host cell modification by malaria parasites. Furthermore, we highlight a number of genes that appear to be essential for blood‐stage survival of these parasites.
Nina Küster, Lena Roling, Ardin Ouayoue, Katharina Steeg, Jude M. Przyborski   +4 more
wiley   +1 more source