Results 161 to 170 of about 251,198 (269)

Broadening horizons: Pathogenesis and therapeutics of renal ciliopathies

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
This review elucidates the molecular mechanisms and aberrant signaling pathways in renal ciliopathies, links genetic heterogeneity to clinical phenotypes, and lays a theoretical basis for prenatal diagnosis and novel therapies. Abstract Renal ciliopathies encompass a spectrum of genetic disorders arising from structural or functional impairments of ...
Qiaowei Zhang   +7 more
wiley   +1 more source

Integrated Genomic and Proteomic Analysis Reveals T‐B Lymphocyte Signatures in the MYCN Driven “Immune Desert” of Specific Neuroblastoma Subtypes

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
This study identifies a high‐risk neuroblastoma subtype defined by MYCN amplification and an “immune desert” tumor microenvironment. We uncover novel lymphocyte‐specific immunosuppressive networks, including T cell dysfunction and a MYC‐driven B cell hub, revealing potential therapeutic targets.
Jia‐Jian Hu   +5 more
wiley   +1 more source

Sigma Gamma Rho Keychain

open access: yes
This is a Sigma Gamma Rho keychain. It is clear plexiglass that has been cut into a rectangle. It has the sorority's Greek letters etched into the surface.Sigma Gamma Rho was founded at Butler University in 1922; in 1929 the organization was established ...
Sigma Gamma Rho Sorority, Inc.
core   +1 more source

The role of Rho GTPase family in cochlear hair cells and hearing. [PDF]

open access: yesNeural Regen Res, 2023
Dai YB, Gao X, Liu D, Gong J.
europepmc   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

open access: yesEquine Veterinary Journal, Volume 58, Issue 5, Page 1413-1444, September 2026.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska   +4 more
wiley   +1 more source

Unveiling the Functional Role of KIF21B in Microglia Inflammatory Response

open access: yesGlia, Volume 74, Issue 9, September 2026.
Microglia express KIF21B in both sexes. KIF21B binds to microglia cytoskeleton; inflammation alters such interaction promoting a phagocytic state in females. In male microglia KIF21B modulates migration. ABSTRACT Microglia are brain immune cells that maintain homeostasis and respond to injury, changing cell morphology to drive inflammation, migration ...
Danny Ganchala   +6 more
wiley   +1 more source

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

open access: yesiMetaOmics, Volume 3, Issue 3, September 2026.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang   +16 more
wiley   +1 more source

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