Results 171 to 180 of about 251,198 (269)

Mebendazole Attenuates Cellular Invasion in a 3D Culture Model of Meningioma by Disrupting Rho-GTPase-Mediated Microtubule Function. [PDF]

Oncol Res
James MM, Clara Elena LV, Agadha W, Chuen CAH, Lee GC.   +4 more
europepmc   +1 more source

Host‐to‐Pathogen Transfer of Neutrophil Components via Extracellular Vesicles Shields Candida albicans From Immune Attack in Human Blood

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Neutrophils release extracellular vesicles (EVs) in response to Candida albicans, and these EVs bind to the fungus in a complement‐dependent manner while carrying neutrophil surface markers and antimicrobial proteins. Despite this cargo, EV coating does not inhibit fungal growth but markedly reduces neutrophil phagocytic uptake in purified‐cell assays ...
Jennifer J. Patitz, Natalie E. Nieuwenhuizen, Anastasia Solomatina, Yann Bachelot, Thomas Krüger, Carl‐Magnus Svensson, Stephanie Hoeppener, Ann‐Kathrin Zimmermann, Matthew G. Blango, Ronny Martin, Olaf Kniemeyer, Theresa Lange, Axel A. Brakhage, Marc Thilo Figge, Oliver Kurzai, Kerstin Hünniger‐Ast   +15 more
wiley   +1 more source

Ion Channel-Rho GTPase Coupling in Human Odontogenesis: Integrative Structural and Network Dissection of TRIO and CACNA2D2 Variants From Familial Tooth Agenesis. [PDF]

Cureus
Nabbout F, Sabbagh J, El Hajj J, Ghassibe M.   +3 more
europepmc   +1 more source

Spatiotemporal regulation of Rho GTPase signaling during endothelial barrier remodeling. [PDF]

Curr Opin Physiol, 2023
van der Krogt JM, van der Meulen IJ, van Buul JD.   +2 more
europepmc   +1 more source

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

MedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang, Yin Zhu, Fang Xu, Yongjing Liu, Yuan Li, Ling Yuan, Liqin Wei, Bo Huang, Yan Chen, Pei Huang, Zuochen Du   +10 more
wiley   +1 more source

Növényi RHO (ROP) GTP-áz aktivált kinázok azonosítása és jellemzése [PDF]

, 2009
Dorjgotov Dulguun
core  

Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 9, September 2026.
Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li, Qian Zhang, Yichen Wu, Ruixue Huang   +3 more
wiley   +1 more source

Integrated Methylome-Transcriptome Analysis Reveals Epigenomic Remodeling and Rho GTPase-Linked Immune-Epithelial Crosstalk in Atopic Dermatitis. [PDF]

Allergy
Skoog T, Yang Y, Olah P, Katayama S, Karisola P, Smith C, Weidinger S, Barker J, Lauerma A, Andersson B, Homey B, Fyhrquist N, Kere J, Alenius H, MAARS Consortium.   +14 more
europepmc   +1 more source

Rho GTPase activity crosstalk mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles. [PDF]

Nat Commun, 2023
Nanda S, Calderon A, Sachan A, Duong TT, Koch J, Xin X, Solouk-Stahlberg D, Wu YW, Nalbant P, Dehmelt L.   +9 more
europepmc   +1 more source

Metabolism in Tumor: Mechanisms and Therapeutic Perspectives

MedComm, Volume 7, Issue 9, September 2026.
Tumor metabolic reprogramming converges on three hubs—the SREBP1/2–FASN–SCD1 lipogenic axis, the HIF‐1α–GLUT1–LDHA glycolytic axis, and the LDLR–SCARB1–LXR cholesterol system—which integrate transcriptional, epigenetic (histone lactylation, m6A), and microenvironmental inputs to generate metabolic plasticity, immune evasion, and therapy resistance ...
Jia‐Chen Cheng, Yi‐Xuan Hu, Xiang‐Chun Huang, Shan Jiang, Jie‐Lin Wang, Yang Zhao, Shuo Chen   +6 more
wiley   +1 more source