Results 171 to 180 of about 49,205 (203)
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Rho GTPases in hepatocellular carcinoma
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2009Rho GTPases are major regulators of signal transduction pathways and play key roles in processes including actin dynamics, cell cycle progression, cell survival and gene expression, whose deregulation may lead to tumorigenesis. A growing number of in vitro and in vivo studies using tumor-derived cell lines, primary tumors and animal cancer models ...
Florence, Grise +2 more
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Nature, 2002
Rho GTPases are molecular switches that control a wide variety of signal transduction pathways in all eukaryotic cells. They are known principally for their pivotal role in regulating the actin cytoskeleton, but their ability to influence cell polarity, microtubule dynamics, membrane transport pathways and transcription factor activity is probably just
Sandrine, Etienne-Manneville, Alan, Hall
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Rho GTPases are molecular switches that control a wide variety of signal transduction pathways in all eukaryotic cells. They are known principally for their pivotal role in regulating the actin cytoskeleton, but their ability to influence cell polarity, microtubule dynamics, membrane transport pathways and transcription factor activity is probably just
Sandrine, Etienne-Manneville, Alan, Hall
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Trends in Genetics, 1994
Ras-related GTP-binding proteins (GTPases) of the rho subfamily play important roles in regulating the organization of the actin cytoskeleton. A large number of multifunctional proteins that can stimulate their intrinsic GTPase activity have been identified.
N, Lamarche, A, Hall
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Ras-related GTP-binding proteins (GTPases) of the rho subfamily play important roles in regulating the organization of the actin cytoskeleton. A large number of multifunctional proteins that can stimulate their intrinsic GTPase activity have been identified.
N, Lamarche, A, Hall
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1999
It is becoming increasingly clear that the complex family of Rho-related GTPases and their associated regulators and targets are essential mediators of a variety of morphogenetic events required for normal development of multicellular organisms. It is worth noting that the results obtained thus far indicate that the Rho family proteins are largely ...
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It is becoming increasingly clear that the complex family of Rho-related GTPases and their associated regulators and targets are essential mediators of a variety of morphogenetic events required for normal development of multicellular organisms. It is worth noting that the results obtained thus far indicate that the Rho family proteins are largely ...
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The Immunological Synapse and Rho GTPases
2005Rho GTPases are molecular switches controlling a broad range of cellular processes including lymphocyte activation. Not surprisingly, Rho GTPases are now recognized as pivotal regulators of antigen-specific T cell activation by APCs and immunological synapse formation.
M, Deckert, C, Moon, S, Le Bras
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Rho GTPases and macrophage phagocytosis
2000Publisher Summary This chapter describes Rho guanosine 5'-triphosphates (GTPases) and macrophage phagocytosis. Phagocytosis is the conserved process whereby cells recognize and engulf large particles. It plays a crucial role in diverse functions ranging from feeding in Dictyostelium to removal of apoptotic cells and to host defense mechanisms in ...
J C, Patel, A, Hall, E, Caron
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Rho GTPases and the Actin Cytoskeleton
Science, 1998The actin cytoskeleton mediates a variety of essential biological functions in all eukaryotic cells. In addition to providing a structural framework around which cell shape and polarity are defined, its dynamic properties provide the driving force for cells to move and to divide. Understanding the biochemical mechanisms that control the organization of
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Plant Rho GTPase signaling promotes autophagy
Molecular Plant, 2021Yonglun Zeng, Ying Zhu, Jinbo Shen
exaly