Results 151 to 160 of about 72,889 (250)
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
The FEBS Journal, EarlyView.Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
DOCK4 Regulation of Rho GTPases Mediates Pulmonary Vascular Barrier Function. [PDF]
Arterioscler Thromb Vasc Biol, 2022 Yazbeck P +12 more
europepmc +1 more source
Immunology, EarlyView.RNA‐seq of lungs and livers from Mycobacterium tuberculosis‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and ...
Felipe T. Lima +9 more
wiley +1 more source
Role of Rho GTPases in stem cell regulation. [PDF]
Biochem Soc Trans, 2021 Zhang Z, Liu M, Zheng Y.
europepmc +1 more source
Immunology, EarlyView.A cumulative genetic score based on IgG4‐associated variants explains a substantial proportion of variance in psIgG4 levels during sustained peanut consumption, highlighting strong gene‐by‐environment interactions. Our findings suggest that early, sustained peanut consumption, in combination with genetic factors, promotes a protective immune response ...
Kanika Kanchan +14 more
wiley +1 more source
Crystal Structure of Schizosaccharomyces pombe Rho1 Reveals Its Evolutionary Relationship with Other Rho GTPases. [PDF]
Biology (Basel), 2022 Huang Q, Xie J, Seetharaman J.
europepmc +1 more source
Journal of Periodontal Research, EarlyView.The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag +6 more
wiley +1 more source
Rho GTPases in Skeletal Muscle Development and Homeostasis. [PDF]
Cells, 2021 Rodríguez-Fdez S, Bustelo XR.
europepmc +1 more source
ELMO1 has an essential role in the internalization of Salmonella Typhimurium into enteric macrophages that impacts disease outcome. [PDF]
, 2015 Backgrounds and aims4-6 million people die of enteric infections each year. After invading intestinal epithelial cells, enteric bacteria encounter phagocytes.
Casanova, James E +9 more
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