Results 161 to 170 of about 191,346 (272)

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

The FEBS Journal, EarlyView.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini, Hira Khursheed, Wen Wei Zhang, Isabelle Aubry, Greg Matlashewski, Michel L. Tremblay, Patrick Lypaczewski   +6 more
wiley   +1 more source

Patterning of the cell cortex by Rho GTPases

Nature reviews. Molecular cell biology
W. Bement, A. Goryachev, Ann L. Miller, G. von Dassow   +3 more
semanticscholar   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Seeing is believing: tools to study the role of Rho GTPases during cytokinesis. [PDF]

Small GTPases, 2022
Koh SP, Pham NP, Piekny A.
europepmc   +1 more source

Spatial Transcriptomic Assessments of Gene Expression Profiles in Human Peri‐Implant Lesions

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To analyse gene expression profiles in human tissue samples obtained from dental implant sites with or without peri‐implantitis. Materials and Methods Soft‐tissue biopsy samples obtained from patients presenting with implants with severe peri‐implantitis and adjacent reference implants with no signs of peri‐implantitis were analysed by ...
C. Dionigi, A. C. Ericson, A. Shikhan, L. Larsson, T. Berglundh   +4 more
wiley   +1 more source

Friend leukemia virus integration 1 activates the Rho GTPase pathway and is associated with metastasis in breast cancer

, 2015
Wei Song, Wěi Li, Lingyu Li, Shilin Zhang, Yan Xu, Wen Xue, Xiaoying Zhang, Huimin Tian, Ailing Li, Ji‐Fan Hu, Jiuwei Cui   +10 more
openalex   +2 more sources

Somatic mutations in IRE1α regulate keratinocyte migration and survival by differentially activating Rho GTPases. [PDF]

J Cell Sci
Mogre S, Robinson L, Sethia K, Rimal B, Son J, Pacifico C, Santy L, Patterson A, Glick AB.   +8 more
europepmc   +1 more source

Polar‐localized EXO70G1 regulates root development in Arabidopsis thaliana

Journal of Integrative Plant Biology, EarlyView.
The putative exocyst subunit EXO70G1 exhibits apical‐basal polarity in Arabidopsis root cells; this polarity stabilizes membrane domains to facilitate targeting of the auxin transporter PIN‐FORMED2 during root development. ABSTRACT Cellular asymmetry, which represents a fundamental characteristic of cell polarity, is prominently illustrated by the ...
Juan Li, Zhendong Liu, Lixue Gong, Shuju Zhao, Qing Lu, Shan Gao, Su Jiang, Xiaonan Liu, Long Ma, Guangyou Duan, Dayong Cui, Shipeng Li   +11 more
wiley   +1 more source

AuNis modified AlGaN/GaN HEMT biosensor for reliable detection of small Rho GTPases in Jurkat T cell lysate. [PDF]

Sci Rep
Fauzi N, Chong CF, Firdaus A, Kawarada H, Mokhtar AMA, Falina S, Syamsul M.   +6 more
europepmc   +1 more source

The 20 kDa isoform of the human growth hormone variant alters adipose and muscle gene expression differently than human growth hormone

Journal of Neuroendocrinology, EarlyView.
Abstract The 20 kDa isoform of human growth hormone variant (20K hGH‐V) (derived from the GH2 gene) has previously been shown to promote growth but lacks the diabetogenic and lactogenic activities of human GH (derived from the GH1 gene). That is, 20K hGH‐V‐treated mice have similar body size and composition to hGH‐treated mice, as well as improved ...
Jonathan A. Young, Jolie Bogart, Mat Buchman, Silvana Duran‐Ortiz, Stephen Bell, John J. Kopchick, Darlene E. Berryman, Edward O. List   +7 more
wiley   +1 more source