Results 11 to 20 of about 81,016 (339)

Evaluation of Riboflavin Transporters as Targets for Drug Delivery and Theranostics

Frontiers in Pharmacology, 2019
The retention and cellular internalization of drug delivery systems and theranostics for cancer therapy can be improved by targeting molecules. Since an increased uptake of riboflavin was reported for various cancers, riboflavin and its derivatives may ...
David Schumacher, Saskia Von Stillfried, Fabian Kiessling   +2 more
exaly   +4 more sources

Overview on the Bacterial Iron-Riboflavin Metabolic Axis

Frontiers in Microbiology, 2018
Redox reactions are ubiquitous in biological processes. Enzymes involved in redox metabolism often use cofactors in order to facilitate electron-transfer reactions. Common redox cofactors include micronutrients such as vitamins and metals.
Juan Carlos Salazar, D J Mahon, Arefeh Babazadeh   +2 more
exaly   +4 more sources

Riboflavin Production by Steady-State Continuous Cultures of Hyphopichia wangnamkhiaoensis in a Bubble Column Bioreactor [PDF]

Microorganisms
Riboflavin is biosynthesized and excreted extracellularly by the novel yeast Hyphopichia wangnamkhiaoensis. The steady-state kinetics of cell growth, substrate consumption, and riboflavin production by H.
Raziel Arturo Jiménez-Nava, Griselda Ma. Chávez-Camarillo, Eliseo Cristiani-Urbina   +2 more
doaj   +2 more sources

Structure and transport mechanism of human riboflavin transporters [PDF]

Nature Communications
Riboflavin (vitamin B2) is the precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which act as key cofactors of many enzymes, thus has essential roles in cell growth and functions. Animals cannot synthesize riboflavin in situ,
Ke Wang, Huiwen Chen, Lili Cheng, Jun Zhao, Bo Huang, Di Wu, Xin He, Yumeng Zhou, Yaxuan Yuan, Feng Zhou, Juquan Jiang, Ligong Chen, Daohua Jiang   +12 more
doaj   +2 more sources

Screening and Spontaneous Mutation of Pickle-Derived Lactobacillus plantarum with Overproduction of Riboflavin, Related Mechanism, and Food Application

Foods, 2020
Riboflavin, also known as vitamin B2, plays an important role in human cell metabolism and participates in various redox reactions and in energy utilization.
Ying-Ying Ge, Jia-Rong Zhang, Harold Corke, Ren-You Gan   +3 more
doaj   +2 more sources

Riboflavin Biosynthesis and Overproduction by a Derivative of the Human Gut Commensal Bifidobacterium longum subsp. infantis ATCC 15697

Frontiers in Microbiology, 2020
Riboflavin or vitamin B2 is the precursor of the essential coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). Despite increased interest in microbial synthesis of this water-soluble vitamin, the metabolic pathway for riboflavin ...
Ana Solopova, Francesca Bottacini, Elena Venturi degli Esposti, Alberto Amaretti, Alberto Amaretti, Stefano Raimondi, Maddalena Rossi, Maddalena Rossi, Douwe van Sinderen, Douwe van Sinderen   +9 more
doaj   +2 more sources

Biomimetic Remodeling of Microglial Riboflavin Metabolism Ameliorates Cognitive Impairment by Modulating Neuroinflammation

Advancement of science, 2023
Neuroinflammation, for which microglia are the predominant contributors, is a significant risk factor for cognitive dysfunction. Riboflavin (also known as vitamin B2) ameliorates cognitive impairment via anti‐oxidative stress and anti‐inflammation ...
Mengran Zhang, Huaqing Chen, Wenlong Zhang, Yan Liu, Liuyan Ding, Junwei Gong, Runfang Ma, S. Zheng, Yunlong Zhang   +8 more
semanticscholar   +1 more source

Causes and Clinical Sequelae of Riboflavin Deficiency.

Annual review of nutrition, 2023
Riboflavin, in its cofactor forms flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), plays fundamental roles in energy metabolism, cellular antioxidant potential, and metabolic interactions with other micronutrients, including iron ...
H. McNulty, K. Pentieva, M. Ward
semanticscholar   +1 more source

Role of riboflavin biosynthesis gene duplication and transporter in Aeromonas salmonicida virulence in marine teleost fish

Virulence, 2023
Active flavins derived from riboflavin (vitamin B2) are essential for life. Bacteria biosynthesize riboflavin or scavenge it through uptake systems, and both mechanisms may be present.
Hajarooba Gnanagobal, Trung Cao, Ahmed Hossain, Ignacio Vasquez, Setu Chakraborty, Joy Chukwu-Osazuwa, Danny Boyce, María Jesus Espinoza, Víctor Antonio García-Angulo, Javier Santander   +9 more
doaj   +1 more source

Extensive Identification of Bacterial Riboflavin Transporters and Their Distribution across Bacterial Species. [PDF]

PLoS ONE, 2015
Riboflavin, the precursor for the cofactors flavin mononucleotide (FMN) and flavin adenine dinucleotide, is an essential metabolite in all organisms. While the functions for de novo riboflavin biosynthesis and riboflavin import may coexist in bacteria ...
Ana Gutiérrez-Preciado, Alfredo Gabriel Torres, Enrique Merino, Hernán Ruy Bonomi, Fernando Alberto Goldbaum, Víctor Antonio García-Angulo   +5 more
doaj   +1 more source