Results 21 to 30 of about 61,817 (251)
Acta Societatis Botanicorum Poloniae, 2015 The influence of GA3 -on the germination of different-aged lupin seed and α-amylase, protease and ribonuclease activity in the embryonic axis and cotyledons of these seeds were investigated after 24, 48, 72 and 96 h of germination. GA3 treatment of older
T. Mierzwińska
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Viruses, 2020 HIV-1 infection requires life-long treatment and with 2.1 million new infections/year, faces the challenge of an increased rate of transmitted drug-resistant mutations.
Angela Corona +12 more
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Antiviral Ranpirnase TMR-001 Inhibits Rabies Virus Release and Cell-to-Cell Infection In Vitro
Viruses, 2020 Currently, no rabies virus-specific antiviral drugs are available. Ranpirnase has strong antitumor and antiviral properties associated with its ribonuclease activity.
Todd G. Smith +12 more
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Ribonuclease H Renaturation Gel Assay Using a Fluorescent-Labeled Substrate
BioTechniques, 1997 Ribonucleases H (RNases H) are enzymes that specifically degrade the RNA of RNA-DNA hybrids. These enzymes are involved in DNA replication, reverse transcription (RT) and antisense oligodeoxyribonucleotide-mediated arrest of translation.
Li-Ying Han, Wu-Po Ma, Robert J. Crouch
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Purification and Properties of Ribonuclease H of Calf Thymus [PDF]
Proceedings of the National Academy of Sciences, 1973 Ribonuclease H of calf thymus has been purified better than 3000-fold to yield an almost homogeneous preparation. The enzyme, which comprises about 0.03% of the total protein in the initial extract, is a slightly acidic protein (pI = 4.95) of molecular weight of about 64,000, possibly composed of subunits. The enzyme requires a metal ion for activation;
J G, Stavrianopoulos, E, Chargaff
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3,7-Dihydroxytropolones Inhibit Initiation of Hepatitis B Virus Minus-Strand DNA Synthesis
Molecules, 2020 Initiation of protein-primed (-) strand DNA synthesis in hepatitis B virus (HBV) requires interaction of the viral reverse transcriptase with epsilon (ε), a cis-acting regulatory signal located at the 5’ terminus of pre-genomic RNA (pgRNA), and several ...
Ellen Bak +6 more
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HIV-1 RT-Associated RNase H review
Archives of Pharmaceutical Sciences Ain Shams University, 2018 HIV-RT is an essential enzyme for HIV replication it comprises two associated functions: RNA- and DNA-dependent DNA polymerase (RDDP & DDDP) and ribonuclease H (RNase H).
Madonna M. A. Mitry +2 more
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An assay of ribonuclease H, endoribonucleases, and phosphatases. [PDF]
Proceedings of the National Academy of Sciences, 1976 An assay for ribonuclease H (EC 3.1.4.34) is described which permits the estimation of the number and the type of cleavages produced by the enzyme when acting on the ribo moiety of a DNA-RNA hybrid substrate. With six different homopolymer hybrids tested, the number of enzymically induced breaks varied widely.
J G, Starvianopoulos, E, Chargaff
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Folding of an isolated ribonuclease H core fragment [PDF]
Protein Science, 1999 AbstractBased on results from both equilibrium and kinetic hydrogen exchange studies of Escherichia coli ribonuclease HI (RNase H), a fragment of RNase H (eABCD) was designed. The sequence of eABCD contains less than half of the protein's primary sequence and includes the regions that were shown to be the most protected from hydrogen exchange in all ...
A K, Chamberlain +4 more
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Evolution of ribonuclease H genes in prokaryotes to avoid inheritance of redundant genes
BMC Evolutionary Biology, 2007 Background A theoretical model of genetic redundancy has proposed that the fates of redundant genes depend on the degree of functional redundancy, and that functionally redundant genes will not be inherited together.
Tomita Masaru +2 more
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