Results 41 to 50 of about 2,736,514 (278)
Regulation of ribonuclease III processing by double-helical sequence antideterminants. [PDF]
Proceedings of the National Academy of Sciences, 1997 The double helix is a ubiquitous feature of RNA molecules and provides a target for nucleases involved in RNA maturation and decay. Escherichia coli ribonuclease III participates in maturation and decay pathways by site-specifically cleaving double-helical structures in cellular and viral RNAs.
Kejing Zhang, Allen W. Nicholson
semanticscholar +3 more sources
Role of metallothionein-III following central nervous system damage
Neurobiology of Disease, 2003 We evaluated the physiological relevance of metallothionein-III (MT-III) in the central nervous system following damage caused by a focal cryolesion onto the cortex by studying Mt3-null mice.
Javier Carrasco +7 more
doaj +1 more source
Structural insight into the Csx1–Crn2 fusion self-limiting ribonuclease of type III CRISPR system
Nucleic Acids ResearchIn the type III CRISPR system, cyclic oligoadenylate (cOA) molecules act as second messengers, activating various promiscuous ancillary nucleases that indiscriminately degrade host and viral DNA/RNA.
Danping Zhang +4 more
semanticscholar +1 more source
BMC Genomics, 2012 Background MicroRNAs play a vital role in the regulation of gene expression and have been identified in every animal with a sequenced genome examined thus far, except for the placozoan Trichoplax. The genomic repertoires of metazoan microRNAs have become
Maxwell Evan K +4 more
doaj +1 more source
Ultra-high resolution X-ray structure of orthorhombic bovine pancreatic Ribonuclease A at 100K
BMC Chemistry, 2023 The crystal structure of orthorhombic Bovine Pancreatic Ribonuclease A has been determined to 0.85 Å resolution using low temperature, 100 K, synchrotron X-ray data collected at 16000 keV (λ = 0.77 Å). This is the first ultra-high-resolution structure of
David R. Lisgarten +9 more
doaj +1 more source
Frontiers in Microbiology, 2022 Streptococcus mutans constantly coexists with Candida albicans in plaque biofilms of early childhood caries (ECC). The progression of ECC can be influenced by the interactions between S. mutans and C. albicans through exopolysaccharides (EPS).
Yangyu Lu +8 more
doaj +1 more source
Ribonuclease III-mediated processing of specific Neisseria meningitidis mRNAs [PDF]
Biochemical Journal, 2003 Approx. 2% of the Neisseria meningitidis genome consists of small DNA insertion sequences known as Correia or nemis elements, which feature TIRs (terminal inverted repeats) of 26–27 bp in length. Elements interspersed with coding regions are co-transcribed with flanking genes into mRNAs, processed at double-stranded RNA structures formed by TIRs.
DE GREGORIO, ELIANA +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Effects of rnase iii rncs gene deletion on stress response, biofilm formation and virulence of listeria monocytogenes [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019 The ribonuclease III (RNase III) is an important enzyme system that regulates non-coding RNA (ncRNA) levels. In this study, LM-ΔrncS gene deletion strain was investigated by gene overlap extension PCR (SOE-PCR) and homologous recombination techniques ...
Lixia WANG +9 more
doaj +1 more source
Nucleic Acids ResearchType III CRISPR immune systems bind viral or plasmid RNA transcripts and activate Csm3/Cmr4 and Cas10 nucleases to uniquely cleave both invader RNA and DNA, respectively.
Katie A. Johnson +10 more
semanticscholar +1 more source