Results 1 to 10 of about 191,709 (318)

Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority phase 3 trial [PDF]

Lancet, The, 2020
BACKGROUND: Buruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans infection that damages the skin and subcutis. It is most prevalent in western and central Africa and Australia.
William Thompson, Fred Stephen Sarfo, Estelle Marion   +2 more
exaly   +5 more sources

Prevalence, risk factors, and treatment outcomes of isoniazid- and rifampicin-mono-resistant pulmonary tuberculosis in Lima, Peru [PDF]

, 2016
Background : Isoniazid and rifampicin are the two most efficacious first-line agents for tuberculosis (TB) treatment. We assessed the prevalence of isoniazid and rifampicin mono-resistance, associated risk factors, and the association of mono-resistance ...
Gotuzzo, Eduardo, Huaman, Moises A, Otero Vegas, Larissa, Seas, Carlos, Sterling, Timothy R, Van Der Stuyft, Patrick, Villegas, Leonela   +6 more
core   +14 more sources

Incidence of Rifampicin Resistance in Periprosthetic Joint Infection: A Single-Centre Cohort Study on 238 Patients

Antibiotics, 2023
Background. Rifampicin is a pillar in the treatment of periprosthetic joint infection (PJI). However, rifampicin resistance is an increasing threat to PJI treatment.
Stergios Lazarinis, Nils P. Hailer, Josef D. Järhult, Anders Brüggemann   +3 more
doaj   +1 more source

Functional Brain Imaging Reveals Reconstitution of the Central Nervous Itch Network Upon Rifampicin Therapy in Hepatic Pruritus [PDF]

Acta Dermato-Venereologica
Marcel Vetter, Theresa Buchwald, Arnd Dörfler, Clemens Forster, Andreas E. Kremer   +4 more
doaj   +2 more sources

Improved outcome with early rifampicin combination treatment in methicillin-sensitive Staphylococcus aureus bacteraemia with a deep infection focus - a retrospective cohort study. [PDF]

PLoS ONE, 2015
INTRODUCTION:Rifampicin has been used as adjunctive therapy in Staphylococcus aureus bacteraemia (SAB) with a deep infection focus. However, data for prognostic impact of rifampicin therapy is unestablished including the optimal initiation time point. We
Erik Forsblom, Eeva Ruotsalainen, Asko Järvinen   +2 more
doaj   +1 more source

Rifampicin-Induced Hepatic Lipid Accumulation: Association with Up-Regulation of Peroxisome Proliferator-Activated Receptor γ in Mouse Liver. [PDF]

PLoS ONE, 2016
Previous study found that rifampicin caused intrahepatic cholestasis. This study investigated the effects of rifampicin on hepatic lipid metabolism. Mice were orally administered with rifampicin (200 mg/kg) daily for different periods.
Jia-Hui Huang, Cheng Zhang, Da-Gang Zhang, Lu Li, Xi Chen, De-Xiang Xu   +5 more
doaj   +1 more source

Combining LAMP and Au-Nanoprobe to detect INH-RIF resistance accurately in tuberculosis: an evidence-based review

Journal of Infection in Developing Countries, 2021
Approximately 1.41 million people die annually due to tuberculosis. One of the main problems in Tuberculosis eradication is the development of resistance to various antibiotics.
Muhammad Habiburrahman, Haekal Ariq, Raden Rara Diah Handayani   +2 more
doaj   +1 more source

GENE MUTATION PATTERNS OF RIFAMPICIN IN MULTIDRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS COMPLEX STRAINS

İstanbul Tıp Fakültesi Dergisi, 2022
Objective: The aim of this study was to evaluate the GenoType®MTBDRplus test for detection of rifampicin (RIF) resistance in MDR Mycobacterium tuberculosis complex strains.
Esra Yıldırım Servi, Meltem Uzun
doaj   +1 more source

Relationship between rifampicin resistance and RpoB substitutions of Rhodococcus equi strains isolated in France

Journal of Global Antimicrobial Resistance, 2020
Objectives: Study of the rifampicin resistance of Rhodococcus equi strains isolated from French horses over a 20-year period. Methods: Rifampicin susceptibility was tested by disk diffusion (DD) and broth macrodilution methods, and rpoB gene sequencing ...
Sandrine Petry, Corinne Sévin, Sofia Kozak, Nathalie Foucher, Claire Laugier, Maud Linster, Marie-France Breuil, Marie-Capucine Dupuis, Aymeric Hans, Fabien Duquesne, Jackie Tapprest   +10 more
doaj   +1 more source

Evaluation of Effectiveness of a New Kit of Reagents for Detection of Mutations Associated with Drug Resistance of Tuberculous Mycobacteria to Rifampicin and Isoniazid, by PCR according to Evidences of Clinical Trials

Туберкулез и болезни лёгких, 2023
The objective: to evalute effectiveness in clinical trials of the new kit of reagents of AmpliTest® MBT-Resist-I based on real-time PCR (RT-PCR) versus similar kits of reagent registered in Russia, to identify genetic markers of M.
Yu. L. Mikulovich, Yu. A. Savochkina, A. I. Zaytseva, A. E. Panova, A. S. Vinokurov, G. A. Shipulin   +5 more
doaj   +1 more source