Rapid Identification of Drug-Resistant Strains of Mycobacterium leprae through qPCR High-Resolution Melt Analysis (HRMA): A High-Throughput and Effective Screening Method. [PDF]
Sharma R, Singh I, Gupta S.
europepmc +1 more source
ABSTRACT Introduction Poor glycaemic control, indicated by a haemoglobin A1c (HbA1c) level of 7% or higher, increases the risk of active tuberculosis (TB) in patients with diabetes, while active TB can worsen glucose tolerance and insulin resistance, contributing to type‐2 diabetes mellitus (DM) progression.
Augustine Asare Boadu +11 more
wiley +1 more source
Drug Interactions Are Crucial in the Care of Patients on Opioid Substitutional Therapy-A Case Report. [PDF]
Devarapalli SK +3 more
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Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
Rechallenge with First-Line Anti-Tubercular Therapy After Toxic Epidermal Necrolysis in an HIV-Positive Patient with Tubercular Pleural Effusion. [PDF]
Narula AS +3 more
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Stimuli‐Responsive Poly(Disulfide)s: A Versatile Platform for Intelligent Drug Delivery Systems
Ring‐opening polymerization based on dynamic disulfide bond exchange is an important method for synthesizing poly(disulfide)s. These polymers possess stimulus‐responsive mechanisms and show broad prospects in intelligent drug delivery. This review systematically discusses the ring‐opening polymerization strategy and research progress of drug delivery ...
Yuechen He +7 more
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Inhalable Chitosan Microparticles: A Spray-Drying Approach for Enhanced Pulmonary Delivery of Rifampicin. [PDF]
Ahmad MS +7 more
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ABSTRACT A precise, robust, and stability‐indicating liquid chromatographic (LC) method coupled with a photodiode array (PDA) detector was developed and validated for the quantitative estimation of rifapentine, an essential therapeutic agent for both active and latent tuberculosis (TB).
Siva Prasad Korikana +5 more
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Phenotypic drug resistance and genome sequencing based identified mutations linked to resistance in Mycobacterium tuberculosis isolated from extrapulmonary clinical specimens. [PDF]
Mollalign H +14 more
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Demyelinating Leprosy Neuropathy: An Unusual and Misleading Electrophysiological Pattern
ABSTRACT Introduction/Aims Peripheral neuropathy, especially mononeuropathy multiplex, is a frequent manifestation of leprosy. Electrodiagnostic studies (EDX) usually show predominant axonal involvement. In this study, we report patients with prominent demyelinating abnormalities consistent with the diagnosis of chronic inflammatory demyelinating ...
Cendrine Foucard +4 more
wiley +1 more source

